Research
Research Faculty Back
Chen Gao
Position Vice Chair of Neurosurgery
Department Neurosurgery
Medical School
Zhejiang%20University%2C%20School%20of%20Medicine%2C%20Hangzhou%2C%20Zhejiang
Academic Rank
Chief Physician
Clinical Interests
Cerebral vascular diseases, Spontaneous subarachnoid hemorrhage (SAH), intracranial aneurysm, Brain tumor, Brain trauma, Hydrocephlus
Professional Highlights
Dr. Gao Chen is especially expert in the open surgery of cerebral vascular diseases: e.g. clipping of intracranial aneurysms, resection of arteriovenous malformation, resection of hemangioma. 
Dr. Gao Chen is also one of the most enthusiastic advocators of emergency management of spontaneous subarachnoid hemorrhages. His endeavor has been paid back by the reduced mortality of spontaneous subarachnoid hemorrhages in Zhejiang Province. His experience in this field has been shared by more and more colleagues in Neurosurgery around Zhejiang Province. 
Publications
Melatonin-enhanced autophagy protects against neural apoptosis via a mitochondrial pathway in early brain injury following a subarachnoid hemorrhage. Chen J, Gao Chen. J Pineal Res. 2013 Aug 12. 
Inhibiting HIF-1α by 2ME2 ameliorates early brain injury after experimental subarachnoid hemorrhage in rats. Chen Wu, Gao Chen. Biochem Biophys Res Commun. 2013 Aug 2;437(3):469-74  
Induction of Autophagic Cell Death in the Rat Brain Caused by Iron. Gao Chen Wang Lin.American Journal of the Medical Sciences. 2013 May;345(5):369-74.
Progesterone attenuates early brain injury after subarachnoid hemorrhage in rats. Feng Yan, Gao Chen. Neurosci Lett. 2013 May 24;543:163-7
Effects of Thioredoxin-1 on Neurogenesis after Brain Ischemia/Reperfusion Injury, Liu PP, Gao Chen, CNS Neurosci Ther. 2013 Mar;19(3):204-5. 
Autophagy activation is associated with neuroprotection against apoptosis via a mitochondrial pathway in a rat model of subarachnoid hemorrhage. Jing Ch, Gao Chen, Neuroscience. 2012 Jun 28;213:144-53.
Postconditioning with sevoflurane protects against focal cerebral ischemia and reperfusion injury via PI3K/Akt pathway. Wang JK Chen gao Brain Res. 2010 Oct 21;1357:142-51.
Diagnosis and management of pituitary abscess: experiences from 33 cases Clin Endocrinol (Oxf). Liu FY. Chen gao 2011 Jan;74(1):79-88
Hypernatremia severity and the risk of death after traumatic brain injury. Li Ming, Chen gao Injury. 2013 Sep;44(9):1213-8. 
Edaravone reduces brain oedema and attenuates cell death after intracerebral haemorrhage in mice; Zhou Feng; Chen Gao; Zhang Jianmin Brain Injury; 02699052; 2009; 23.4
Chronic subdural hematoma associated with arachnoid cyst: report of two cases.Chin Med J (Engl). 2007 Dec 20;120(24):2339-40.
Bowel perforation secondary to ventriculoperitoneal shunt£ļcase report and clinical analysis. J Int Med Res. 2007 Nov-Dec;35(6):926-9.
Development of antibody-based assays for omega conotoxin MVIIA. J Biochem Biophys Methods,2006,67(1):49-56(SCI). 
An in vitro culturing model for rabbit dural cells. Ann Clin Lab Sci. 2006 Summer;36(3):341-4
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