Research Faculty Back
Cai Xunzi
Position Associate Chief Physician
Department Orthopedics
Medical School
Academic Rank
Associate Chief Physician
Clinical Interests
Joint surgery and sports medicine.
Professional Highlights
2012.9–2013.12, clinical fellowship at Royal United Hospital, Bath, UK. 
2012  Awarded Fellowship of Talent Development by Zhejiang Association for Science and Technology. 
Professional Appointments
Editorial Board Member of International Journal of Orthopaedics 
Peer reviewer of Clinical Orthopaedics and Related Research

Zhu HX, Cai XZ (Corresponding Author). CORR Insights: Addition of Vancomycin to Cefazolin Prophylaxis Is Associated with Acute Kidney Injury After Primary Joint Arthroplasty. Clin Orthop Relat Res. 2015; 473(7): 2204-2206.
Wang C, Cai XZ, Yan SG. Comparison of Periarticular Multimodal Drug Injection and Femoral Nerve Block for Postoperative Pain Management in Total Knee Arthroplasty: A Systematic Review and Meta-Analysis. J Arthroplasty. 2015 Feb 20. pii: S0883-5403(15)00116-3.
Zhu H, Cai X, Lin T, Shi Z, Yan S. Low-intensity Pulsed Ultrasound Enhances Bone Repair in a Rabbit Model of Steroid-associated Osteonecrosis. Clin Orthop Relat Res. 2015; 473(5):1830-9.
Lin T, Cai XZ, Shi MM, Ying ZM, Hu B, Zhou CH, Wang W, Shi ZL, Yan SG. In Vitro and In Vivo Evaluation of Vancomycin-Loaded PMMA Cement in Combination with Ultrasound and Microbubbles-Mediated Ultrasound. Biomed Res Int. 2015;2015:309739.
Hu B, Cai XZ, Shi ZL, Chen YL, Zhao X, Zhu HX, Yan SG. Microbubble injection enhances inhibition of low-intensity pulsed ultrasound on debris-induced periprosthetic osteolysis in rabbit model. Ultrasound Med Biol. 2015; 41(1): 177-86.
Zhu HX, Cai XZ, Shi ZL, Hu B, Yan SG. Microbubble-mediated ultrasound enhances the lethal effect of gentamicin on planktonic Escherichia coli. Biomed Res Int. 2014; 2014:142168. doi: 10.1155/2014/142168.
Xue XH, Yan SG, Cai XZ (Corresponding Author), Shi MM, Lin T. Intramedullary nailing versus plating for extra-articular distal tibial metaphyseal fracture: A systematic review and meta-analysis. Injury. 2014; 45(4):667-76.
Lin T, Yan SG, Cai XZ (Corresponding Author), Ying ZM, Yuan FZ, Zuo X. Alendronate versus raloxifene for postmenopausal women: a meta-analysis of seven head-to-head randomized controlled trials. Int J Endocrino. 2014; 2014:796510. doi: 10.1155/2014/796510.
Cai XZ, Yan SG, Giddins G. A systematic review of the non-operative treatment of nightstick fractures Bone Joint J. 2013; 95(7): 952-9.
Shi MM, Cai XZ (First Co-author), Lin T, Wang W, Yan SG, Is There Really No Benefit of Vertebroplasty for Osteoporotic Vertebral Fractures? Clin Orthop Relat Res. 2012; 470(10): 2785-99.
Lin T, Yan SG, Cai XZ (Corresponding Author), Ying ZM. Bisphosphonates for Periprosthetic Bone Loss after Joint Arthroplasty. Osteoporosis Int. 2012; 23(6):1823-34.
Zhao X, Cai XZ, Shi ZL, Zhu FB, Zhao GS, Yan SG. Low-Intensity Pulsed Ultrasound (LIPUS) May Prevent Polyethylene Induced Periprosthetic Osteolysis In Vivo. Ultrasound Med Biol. 2012; 38(2): 238-46.
Lin T, Wang C, Cai XZ, Zhao X, Shi MM, Ying ZM, Yuan FZ, Guo C, Yan SG. Clinical Efficacy and Safety Differences between Denosumab and Alendronate in Postmenopausal Women with Low Bone Mineral Density and Osteoporosis: A Meta-Analysis. Int J Clin Pract. 2012; 66(4): 399-408.
Zhong C, Cai XZ, Yan SG, He RX. S-ROM modular arthroplasty combined with transverse subtrochanteric shortening for Crowe type IV congenital dislocation of hip. Chin Med J. 2011; 124(23):3891-5.
Zhao X, Lin T, Cai XZ, Yan SG. Comparison of minimally invasive surgery (MIS) and mini-incision technique for total hip arthroplasty: a sub-group meta-analysis. Chin Med J. 2011; 124(24):4316-23.
Lin T, Yan SG, Wang C, Cai XZ. Identifying multiple reports from the same study. Orthopedics. 2011; 34(11): 837-8.
Yan SG, Huang LY, Cai XZ (Corresponding Author). Low-Intensity Pulsed Ultrasound: a Potential Non-invasive Therapy for Femoral Head Osteonecrosis. Medical Hypotheses. 2011; 76(1): 4-7.
Zhu FB, Cai XZ (First Co-author), Yan SG, Zhu HX, Li R. The effects of local and systemic alendronate delivery on wear debris-induced osteolysis in vivo. J Orthop Res. 2010; 28(7): 893-9.
Cai XZ, Jin AD, Yan SG. Did local teicoplanin delivery systems inhibit or aggravate implant-related infection? Int Orthop. 2010; 34(3): 453-4.
Cai XZ, Chen XZ, Yan SG. Cemented hemiarthroplasty confers less pain and better mobility than uncemented hemiarthroplasty. Clin Orthop Relat Res. 2009; 467(2): 582-584.
Cai XZ, Chen XZ, Yan SG, Ruan ZR, Yan RJ, Ji K, Xu J. Special Report: Intermittent watt-level ultrasonication facilitates vancomycin release from therapeutic acrylic bone cement. J Biomed. Mater. Res. 2009; 90B(1): 11-17.
Chen XZ, Zhu KJ, Xu Y, Tang XY, Cai XZ, Zhang X, Cheng H. RNA interference silences the human papillomavirus 6b/11 early gene E7 in vitro and in vivo. Clin Exp Dermatol. 2009 Oct 23.
Cai XZ, Chen XZ, Yan SG. Efficacy of antibiotic-impregnated cement in total hip replacement. Acta Orthop. 2008; 79(6): 870-872.
Yan SG, Cai XZ, Yan WQ, Dai XS, Wu HB. Continuous wave ultrasound enhances vancomycin release and antimicrobial efficacy of antibiotic-loaded acrylic bone cement in vitro and in vivo. J Biomed. Mater. Res. 2007; 82B(1): 57-64.
Cai XZ, Yan SG, Wu HB, He RX, Dai XS, Chen HX, Yan RJ, Zhao XH.  Enhancement of Delayed Pulsed Wave Ultrasound on Local Pharmacokinetics and Pharmacodynamics of Vancomycin-Loaded Acrylic Bone Cement in Vivo. Antimicrob Agents Chemother. 2007; 51(9): 3199-3204.

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