Research
Research Faculty Back
Chen Yiding
Position Vice Chair of Surgical Oncology, Director of Breast Surgery
Department Surgical Oncology
Medical School
Zhejiang%20University%20School%20of%20Medicine%2C%20Zhejiang%2C%20China%20%0D%0A
Academic Rank
Chief Physician 
Clinical Interests
Major in benign and malignant breast disease,especially in breast reconstruction and oncoplastic.   
Professional Highlights
First Prize, Reward for Achievement in Scientific Research, Zhejiang Provincial Government, China, 2008
Excellent Young Member of the Zhejiang Preventive Medical Association, 2011
Excellent Young Scholar of Zhejiang University College of Medicine, 2009.
Excellent Young Teacher of Zhejiang University College of Medicine, 2009.
Education Experience
2005.11-2006.12 Postdoctoral  Oncology, Long Island Jewish Medical Center of Einstein Medical school,  USA
2000.9- 2004.6  Ph;M.D  Oncology, Medical College of Zhejiang University, PR China
1994.9- 1997.7   Master Degree of Medical Science  Oncology, Medical College of Zhejiang University, PR China
1989.9- 1994.7  Bachelor of medicine, Zhejiang Medical University, PR China
Research Summary
1. Research on basic and translational in breast carcinoma 
2. Research on hereditary breast cancer 
3. Research on GeneChip Technology and Bioinformatics in Cancer 
4. Principal Investigator in clinical research in breast cancer
Current Program
National Natural Science Foundation of China,Establishing Chemopreventive model and finding intermediate biomarkers of rat colon carcinogenesis based on plasma proteomics.No.: 30500598,CNY250,000.

National Natural Science Foundation of China; Role of the SNCG and it's inhibitor in Kinase signaling transduction pathway of the breast cancer. No.: 30973465, CNY 310,000.

National Natural Science Foundation of China;Vitexin 6, a novel lignin, induces autophagy and apoptosis by activating the JNK pathway.  No.: 81071879, CNY 330,000.

Publications

Xu W, Hu Y, He X, Li J, Pan T, Liu H, Wu X, He H, Ge W, Yu J, Wei Q, Zheng S, Zhang S, Chen Y. Serum profiling by mass spectrometry combined with bioinformatics for the biomarkers discovery in diffuse large B-cell lymphoma. Tumour Biol. 2014 Nov 20. [Epub ahead of print] (Corresponding author)
Shao Y, Wang B, Shi D, Miao S, Manivel P, Krishna R, Chen Y, Eric Shi Y. Synuclein gamma protects HER2 and renders resistance to Hsp90 disruption. Mol Oncol. 2014 Dec;8(8):1521-31 (Corresponding author)
Liang W, Miao S, Zhang B, He S, Shou C, Manivel P, Krishna R, Chen Y, Shi YE. Synuclein γ protects Akt and mTOR and renders tumor resistance to Hsp90 disruption. Oncogene. 2014 Jun 23;0. doi: 10.1038/onc.2014.126. [Epub ahead of print] (Corresponding author)
Qian X, Chen Y, Wan F. Granular cell tumor of the breast during lactation: A case report and review of the literature. Oncol Lett. 2014 Dec;8(6):2565-2568
Chen X, Ye G, Zhang C, Li X, Chen Y, Xie X, Zheng H, Cao Y, Wu K, Ni D, Tang J, Wei Z, Shen K. Superior outcome after neoadjuvant chemotherapy with docetaxel, anthracycline, and cyclophosphamide versus docetaxel plus cyclophosphamide: results from the NATT trial in triple negative or HER2 positive breast cancer. Breast Cancer Res Treat. 2013 Dec;142(3):549-58
Zhou J, Huang Y, Li L, Zhu L, Zhang D, Zhang S, Chen Y. Identification of two novel£¨alternatively spliced mRNA transcripts of human follicle-stimulating hormone receptor. Molecular Reproduction and Development 2013.80(11):916-923(Corresponding author£©
Zhou J, Chen Y, Huang Y, Long J, Wan F, Zhang S. Serum follicle‑stimulating hormone level is associated with human epidermal growth factor receptor type 2 and Ki67 expression in post‑menopausal females with breast cancer. Oncology Letters 2013,6(4): 1128-1132
Zhou J, Hu H, Long J, Wan F, Li L, Zhang S, Shi YE, Chen Y.. Vitexin 6, a novel lignan, induces autophagy and apoptosis by activating the Jun N-terminal kinase pathway. Anti-Cancer Drugs 2013, 24(9):928~936 (Corresponding author)
Wan F, Dong L, Zhang F, Wang Y, Chen F, Ni S, Chen Y, Long J. Clinical study of the relationship between g-synuclein and the response of neoadjuvant chemotherapy in breast cancer. Journal of International Medical Research 2013;41(3):743-53Li L, Zhou J, Qian XJ and Chen Y. Meta-analysis on the possible association between in vitro fertlilization and cancer risk. Int J Gynecol cancer. 2013 ;23(1):16-24. £®Corresponding author£©
Wu J, Chen Y, Yu JK, Shi XL, Gu W.  Analysis of urinary proteomic patterns for type 2 diabetic nephropathy by ProteinChip. Diabetes Res Clin Pract. 2011;91(2):213-9
Shi YE, Chen Y, Dackour R, Potters L, Wang Z and Liu YE. Synuclein gamma stimulates membrane initiated estrogen signaling by chaperoning ER-a36, a variant of ER-a. American J Pathology,.2010,177:964-73£®Co-first Author£©
Chen Y, Chen F, Xie P, Qiu P, Zhou J, Deng Y. Combined Oxidized Cellulose and Cyanoacrylate Glue in the Management of Severe Presacral Bleeding.  Surgery Today. 2009£¨39:1016°ę1017£®First Author£©
Wang H, Ge J, Chen L, Xie P, Chen F, Chen Y. Melanocytic Malignant Peripheral Nerve Sheath Tumor of the Male Breast. Breast care. 2009,4:460-462 £®Corresponding author£©
Zhou Y, Liu Y, Cao J, Zeng, G, Shen C, Li Y, Zhou M, Chen Y, Pu W, Potters L, Shi E. Vitexins, Nature-Derived Lignan Compounds, Induce Apoptosis and Suppress Tumor Growth. Clinical Cancer Research. 2009,15:5161-5170
Gu W, Zhou L, Shan P, Chen Y. Analysis of Urinary Proteomic Patterns for Diabetic Nephropathy by ProteinChip. Proteomics. 2008, 2, 744–750 £®Corresponding author£©
Wu K, Quan Z, Weng Z, Li F, Zhang Y, Yao X, Chen Y, Budman D, Goldberg ID, Shi YE. Expression of neuronal protein synuclein gamma gene as a novel marker for breast cancer prognosis Breast Cancer Research and Treatment. 2007;101:259-67
Guo J, Shou C, Meng L, Jiang B, Dong B, Yao L, Xie Y, Zhang J, Chen Y, Budman DR, Shi YE. Neuronal protein synuclein gamma predicts poor clinical outcome in breast cancer. International Journal of Cancer. 2007;121:1296-305
Chen Y , Zheng S, Yu J£¨Hu X. Artificial Neural Networks Analysis of SELDI Mass Spectra of Serum Protein Pattern Distinguishes Colorectal Cancer from Healthy Population. Clinical Cancer Research 2004.10: 8380-8385£®First Author£©
Chen Y , Zheng S, Yu J, Hu X.  Development of serum biomarker model and its application in colorectal cancer diagnosis.  Journal of Tumor Marker Oncology 2004,19: 251-258 £®First Author£©
Yu J, Chen Y, Zheng S, . An integrated approach utilizing Proteomics and bioinformatics to detect colorectal cancer. World J Gastroenterol, 2004, 10: 3127-3131

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