Departments & Centers
Leadership Back
Liang Tingbo M.D Ph.D FACS
Position£º Vice President of the Hospital for Medical Affairs
Department£º General Surgery
Medical School
Zhejiang%20University%20School%20of%20Medicine%2C%20Zhejiang%2C%20China
Academic Rank
Chief Physician, Professor of Surgery
Clinical Interests
Hepato-biliary-pancreatic Surgery and Liver Transplantation
Professional Highlights
Qiushi Scholar, Zhejiang University, 2012
Yangtze River Scholar, Ministry of Education, 2011
National Hundred, Thousand and Ten Thousand Talent Project Scholar, 2015
Zhejiang High-Level Healthcare Expert, 2010
National Distinguished Young Scholar, 2009
First Class of Institutional Scientific Advance Award, Ministry of Education, 2013
Second Class of National Scientific Advance Award, 2008
Young Scholar with Outstanding Contribution, Chinese Ministry of Health, 2005
Zhejiang Youth Scientific Award, 2005
Zhejiang 151 Scholar First Level, 2004
First Class of Zhejiang Scientific Advance Award, 2000, 2016
Professional Appointments
Changjiang Scholars Professor
Distinguished Professor of Zhejiang University
International Hepato-Pancreto-Biliary Association (IHPBA) China Branch, Board Member
Fellowship of American College of Surgeons, FACS
International and Asian Hepato-Pancreto-Biliary Association (IAHPBA), Board Member
International Liver Transplantation Society (ILTS), Board Member
Chinese Research Hospital Association (CRHA), Enhanced Recovery After Surgery (ERAS) Division, Chair
Chinese Medical Association (CMA) Surgery Branch (Biliary Division), Vice Chair
Chinese Medical Association (CMA) Surgery Branch (Pancreas Division), Board Member
CMA Oncology Branch (Liver Cancer Division), Board Member
Chinese Society of Immunology (CSI) Transplantation Immunology Branch, Chief Secretary
Chinese Anti-cancer Association (CACA) Pancreatic Cancer Branch, Board Member
CACA Liver Cancer Branch, Board Member
CACA Metastasis Branch, Board Member
Chinese Medical Doctor Association (CMDA) Biliary Surgery Branch, Vice Chair
Chinese Research Hospital Association (CRHA), Pancreas Division, Vice Chair
Zhejiang Medical Association (ZMA) Organ Transplantation Branch, Vice Chair
Zhejiang Association of Chinese Integrative Medicine, General Surgery Branch, Vice Chair
Chinese Research Hospital Association (CRHA), Pancreas Division, Vice Chair
Chinese Medical Doctor Association (CMDA), Surgeon Branch (Biliary Surgery Division), Vice Chair
Publications

Over 400 journal articles on liver cancer and pancreatic cancer.
Selected publications(*corresponding author ):
1.      Chen W, Ma T, Shen XN, Xia XF, Xu GD, Bai XL, Liang TB*. Macrophage-induced tumor angiogenesis is regulated by the TSC2-mTOR pathway. Cancer Res, 2012, 72(6): 1363-72.
2.      Bai XL, Zhang Q, Ye LY, Liang F, Sun X, Chen Y, Hu QD, Fu QH, Su W, Chen Z, Zhuang ZP, Liang TB*. Myocyte enhancer factor 2C regulation of hepatocellular carcinoma via vascular endothelial growth factor and Wnt/β-catenin signaling. Oncogene. 2015 Jul 30;34(31):4089-97.
3.      Bai XL, Zhang Q, Ye LY, Hu QD, Fu QH, Zhi X, Su W, Su RG, Ma T, Chen W, Xie SZ, Chen CL, Liang TB*. Inhibition of Protein Phosphatase 2A Enhances Cytotoxicity and Accessibility of Chemotherapeutic Drugs to Hepatocellular Carcinomas. Mol Cancer Ther. 2014 Aug;13(8):2062-72.
4.      Zhang Q, Bai X, Chen W, Ma T, Hu Q, Liang C, Xie S, Chen C, Hu L, Xu S, Liang T*. Wnt/β-catenin signaling enhances hypoxia-induced epithelial-mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling. Carcinogenesis, 2013, 34(5): 962-73. 
5.      Ye LY, Chen W, Bai XL, Xu XY, Zhang Q, Xia XF, Sun X, Li GG, Hu QD, Fu QH, Liang TB*. Hypoxia-induced epithelial-to-mesenchymal transition in hepatocellular carcinoma induces an immunosuppressive tumor microenvironment to promote metastasis. Cancer Res.,2016, 76(4): 818-30.
6.      Bai X, Zhang Q, Gao S, Lou J, Li G, Zhang Y, Ma T, Zhang Y, Xu Y, Liang T*. Duct-to-mucosa vs invagination for pancreaticojejunostomy after pancreaticoduodenectomy: A prospective, randomized controlled trial from a single surgeon. J Am. Coll. Surg., 2016, 222(1): 10-8.
7.      Wen L, Liang C, Chen E, Chen W, Liang F, Zhi X, Wei T, Xue F, Li G, Yang Q, Gong W, Feng X, Bai X, Liang T*. Regulation of multi-drug resistance in hepatocellular carcinoma cells is TRPC6/calcium dependent. Sci Rep. 2016 Mar 24;6:23269.
8.      Liang T, Su W, Zhang Q, Li G, Gao S, Lou J, Zhang Y, Ma T, Bai X. Roles of sphincter of Oddi laxity in bile duct microenvironment in patients with cholangiolithiasis: From the perspective of the microbiome and metabolome. J Am Coll Surg. 2016 Mar;222(3):269-280.e10.
9.      Bai X, Zhang Q, Wu S, Zhang X, Wang M, He F, Wei T, Yang J, Lou Y, Cai Z, Liang T*. Characteristics of Tumor Infiltrating Lymphocyte and Circulating Lymphocyte Repertoires in Pancreatic Cancer by the Sequencing of T Cell Receptors. Sci Rep. 2015 Sep 2;5:13664.
10.   Zhou Y, Liang C, Xue F, Chen W, Zhi X, Feng X, Bai X, Liang T*. Salinomycin decreases doxorubicin resistance in hepatocellular carcinoma cells by inhibiting the β-catenin/TCF complex association via FOXO3a activation. Oncotarget. 2015 Apr 30;6(12):10350-65.
11.   Zhi X, Chen W, Xue F, Liang C, Chen BW, Zhou Y, Wen L, Hu L, Shen J, Bai X, Liang T*. OSI-027 inhibits pancreatic ductal adenocarcinoma cell proliferation and enhances the therapeutic effect of gemcitabine both in vitro and in vivo. Oncotarget. 2015 Jul 21. Epub.
12.   Chen BW, Chen W, Liang H, Liu H, Liang C, Zhi X, Hu LQ, Yu XZ, Wei T, Ma T, Xue F, Zheng L, Zhao B, Feng XH, Bai XL, Liang TB*. Inhibition of mTORC2 Induces Cell-Cycle Arrest and Enhances the Cytotoxicity of Doxorubicin by Suppressing MDR1 Expression in HCC Cells. Mol Cancer Ther. 2015 Aug;14(8):1805-15.
13.   Liu H, Chen W, Liang C, Chen BW, Zhi X, Zhang S, Zheng X, Bai X, Liang T*. WP1130 increases doxorubicin sensitivity in hepatocellular carcinoma cells through usp9x-dependent p53 degradation. Cancer Lett. 2015 Jun 1;361(2):218-25.
14.   Liang C, Chen W, Zhi X, Ma T, Xia X, Liu H, Zhang Q, Hu Q, Zhang Y, Bai X, Liang T*. Serotonin promotes the proliferation of serum-deprived hepatocellular carcinoma cells via upregulation of FOXO3a. Mol Cancer. 2013, 12(1): 14. 
15.   Ma T, Liu H, Chen W, Xia X, Bai X, Liang L, Zhang Y, Liang T*. Implanted adipose-derived stem cells attenuate small-for-size liver graft injury by secretion of VEGF in rats. Am J Transplant, 2012, 12(3): 620-9. 
16.   Hu QD, Chen W, Yan TL, Ma T, Chen CL, Liang C, Zhang Q, Xia XF, Liu H, Zhi X, Zheng XX, Bai XL, Yu XZ, Liang TB*. NSC 74859 enhances doxorubicin cytotoxicity via inhibition of epithelial-mesenchymal transition in hepatocellular carcinoma cells. Cancer Lett, 2012, 325(2): 207-13. 
17.   Li DL, He YY, Alkalei AM, Chen XD, Jin W, Li M, Zhang HK, Liang TB*. Management strategy for spontaneous isolated dissection of the superior mesenteric artery based on morphologic classification. J Vasc Surg. 2014;59(1):165-72.
18.   Chen W, Shen X, Xia X, Xu G, Ma T, Bai X, Liang T*. NSC 74859-mediated inhibition of STAT3 enhances the anti-proliferative activity of cetuximab in hepatocellular carcinoma. Liver Int. 2012 Jan;32(1):70-7. 
19.   Xu G, Wang L, Chen W, Xue F, Bai X, Liang L, Shen X, Zhang M, Xia D, Liang T*. Rapamycin and FK506 differentially modulate Acute Graft-Versus-Host Disease in Rats after Liver Transplantation. Liver Transpl. 2010 Mar;16(3):357-63. 
20.   Liang TB, Li JJ, Li DL, Liang L, Bai XL, Zheng SS. Intraoperative blood salvage and leukocyte depletion during liver transplantation with bacterial contamination. Clin Transplant. 2010 Mar 1;24(2):265-72.    
21.   Zhang Y, Yao HP, Huang FF, Wu W, Gao Y, Chen ZB, Liang ZY, Liang T*. Allicin, a major component of garlic, inhibits apoptosis of vital organ in Trauma/Hemorrhagic shock rats. Crit Care Med. 2008 Dec, 36(12):3226-3232. 
22.   Liang TB, Li DL, Liang L, Li JJ, Bai XL, Yu W, Wang WL, Shen Y, Zhang M, Zheng SS. Intraoperative blood salvage during liver transplantation for hepatocellular carcinoma: efficiency of leukocyte depletion filter to eliminate tumor cells. Transplantation, 2008;85(6):863-9. 
23.   Zhang Y, Liang L, Wu W, Gao Y, Chen ZB, Liang ZY, Liang T*. Resuscitation with hydroxyl starch solution prevents CD4+ T lymphocytes apoptosis and modulates the balance of Th1 and Th2 responses in the rat with traumatic hemorrhagic shock. Shock. 2008 Dec 30(6):692-698. 
24.   Zheng SS, Xu X, Wu J, Chen J, Wang WL, Zhang M, Liang TB, Wu LM. Liver Transplantation for Hepatocellular Carcinoma: Hangzhou Experiences. Transplantation. 2008, 85(12):1726-32.     
25.   Liang T, Xu S, Yu J, Shen K, Li D, Zheng S. Activation pattern of mitogen-activated protein kinases in early phase of different size liver isografts in rats. Liver Transpl, 2005 Dec;11(12):1527-32. 
26.   Liang TB, Man K, Kin-Wah Lee T, Hong-Teng Tsui S, Lo CM, Xu X, Zheng SS, Fan ST, Wong J. Distinct intragraft response pattern in relation to graft size in liver transplantation. Transplantation. 2003, 15;75(5):673-8. 

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