Lou Min, M.D., Ph.D.

Department:Neurology

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Chief Physician, Professor of Neurology


Appointment

Clinical / Research Interests

Diagnosis and treatment of stroke, especially thrombolysis and neuroprotection 

Professional Highlights

Professional Appointments

Secretary, Zhejiang Society of Neurology, 2010-present

Education Experience

Research Summary

Publications

Shi F, Gong X, Liu C, Zeng Q, Zhang M, Chen Z, Yan S, Lou M. Acute Stroke: Prognostic Value of Quantitative Collateral Assessment at Perfusion CT. Radiology, 2019.

Tong L, Guo Z, Ou Y, Yu Y, Zhang X, Tang J, Zhang J, Lou M. Cerebral venous collaterals: A new fort for fighting ischemic stroke? Progress in Neurobiology, 2018.

Chen Z, Zhang M, Shi F, Gong X, Lou M. Pseudo-occlusion of the internal carotid artery predicts poor outcome after reperfusion therapy. Stroke, 49(5):1204-1209, 2018.

Zhou Y, Zhang R, Yan S, Zhang M, Chen Z, Hu H, Zhang M, Bivard A, Lin L, Parsons MW, Lou M. Identification of corticospinal tract lesion for predicting outcome in small perfusion stroke. Stroke, 49(11):2683-2691, 2018.

Yang S, Lou M, Luo B, Jiang W, Liu R. Precision medicine for ischemic stroke, let us move beyond time is brain. Translational stroke research, 9(2):93-95, 2018.

Zhang S, Lai Y, Ding X, Parsons M, Zhang J, Lou M. Absent Filling of Ipsilateral Superficial Middle Cerebral Vein Is Associated With Poor Outcome After Reperfusion Therapy. Stroke, 48(4):907-914, 2017.

Tong L, Shao A, Ou Y, Guo Z, Manaenko A, Dixon BJ, Tang J, Lou M, Zhang J. Recombinant Gas6 augments Axl and facilitates immune restoration in an intracerebral hemorrhage mouse model. Journal of Cerebral Blood Flow and Metabolism, 37(6):1971–1981, 2017.

Zhang R, Zhou Y, Liu C, Zhang M, Yan S, Liebeskind DS, Lou M. Overestimation of susceptibility vessel sign: a predictive marker of stroke cause. Stroke, 48(7):1993-1996, 2017.

Liu K, Yan S, Zhang S, Guo Y, Lou M. Systolic blood pressure variability is associated with severe hemorrhagic transformation in the early stage after thrombolysis. Translational stroke research, 7(3):186-191, 2016.

Bivard, A, Lou, M, Levi, CR, Krishnamurthy, V, Cheng, X, Aviv, RI, McElduff, P; Lin, L, Kleinig, T, O'Brien, B ; Butcher, K; Zhang, J, Jannes, J, Dong, Q, Parsons, MW. Too Good to Treat? Ischemic Stroke Patients with Small Computed Tomography Perfusion Lesions May Not Benefit from Thrombolysis. Annals of neurology, 80(2):286-293, 2016.

Yan S, Chen Q, Xu M , Sun J, Liebeskind DS, Lou M. Thrombus length estimation on delayed Gadolinium–enhanced T1. Stroke, 47(3):756-761, 2016.

Wang B, Yan S, Xu M , Zhang S, Liu K, Hu H, Sun J, Selim M, Lou M. Timing of occurrence is the most important characteristic of spot sign. Stroke, 47(5):1233-1238, 2016.

Yan S, Jin X, Zhang X, Zhang S, Liebeskind, S, D, Lou M. Extensive cerebral microbleeds predict parenchymal hemorrhage and poor outcome after intravenous thrombolysis. Journal of Neurology, Neurosurgery & Psychiatry, 86(11):1267-1272, 2015.

Guo Y, Yan S, Zhang S, Zhang X, Chen Q, Liu K, Liebeskind DS, Lou M. Lower serum calcium level is associated with hemorrhagic transformation after thrombolysis. Stroke, 46(5):1359-1361, 2015.

Yan S, Hu H, Shi Z, Zhang X, Zhang S, Liebeskind DS, Lou M. Morphology of Susceptibility Vessel Sign Predicts Middle Cerebral Artery Recanalization After Intravenous Thrombolysis. Stroke, 45(9):2795-2797, 2014.

Wang S, Lou M, Liu T, Cui DQ, Chen X, Wang Y. Hematoma Volume Measurement in Gradient Echo MRI Using Quantitative Susceptibility Mapping. Stroke, 44(8):2315-2317, 2013.

Lou M, Al-Hazzani A, Goddeau RP, Novak V, Selim M. Relationship between white-matter hyperintensities and hematoma volume and growth in patients with intracerebral hemorrhage. Stroke, 41(1):34-40, 2010.

Lou M, Safdar A, Mehdiratta M, Kumar S, Schlaug G, Searls D, Caplan L, Selim M. The HAT score: a simple grading scale for predicting hemorrhage after thrombolysis. Neurology, 70(18):1417-1423, 2008.

Lou M, Blume A, Zhao Y, Gohlke P, Deuschl G, Herdegen T, Culman J. Sustained blockade of brain AT1 receptors before and after focal cerebral ischemia alleviates neurological deficits and reduces neuronal injury, apoptosis and inflammatory responses in the rat. Journal of Cerebral Blood Flow and Metabolism, 24(5):536-547, 2004. 

Lou M, Eschenfelder CC, Herdegen T, Brecht S, Deuschl G. Therapeutic window for the use of hyperbaric oxygenation in transient focal cerebral ischemia in rats. Stroke, 35(2):578-583, 2004.


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