Publications

Simin Meng, Yi Yu, Shuo Yu, Shiyu Zhu, Mengjia Shi, Meixiang Xiang*, Hong Ma*. Advances in Metabolic Remodeling and Intervention Strategies in Heart Failure. Journal of Cardiovascular Translational Research. 2023, Online ahead.

Wudi Li#, Sheng-an Su#, Jian Chen, Yimin Shen, Hong Ma*, Meixiang Xiang*. EphrinB2 drives osteogenic fate of adult cardiac fibroblasts in a calcium influx dependent manner. American Journal of Physiology Cell Physiology. 2023, 325: C69-C78.

Sheng-an Su#, Yuhao Zhang#, Wudi Li#, Yutao Xi, Yunrui Lu, Jian Shen, Yuankun Ma, Yaping Wang, Yimin Shen, Lan Xie, Hong Ma, Yao Xie*, Meixiang Xiang*. Cardiac Piezo1 Exacerbates Lethal Ventricular Arrhythmogenesis by Linking Mechanical Stress with Ca2+ Handling After Myocardial Infarction. Research. 2023, 6:0165.

Yao Xie#, Chengchen Zhao, Meixiang Xiang*. Flow visualization of a unique case of persistent truncus arteriosus with prolonged survival. European Heart Journal. 2023, 44(20):1841.

Lan Xie#, Jinyong Chen#, Yidong Wang, Chengjiang Jin, Yao Xie, Hong Ma, Meixiang Xiang*. Emerging roles of macrophages in heart failure and associated treatment approaches. Therapeutic advances in chronic disease. 2023, 14: 1-14.

Lan Xie#, Xiying Wang#, Yuankun Ma#, Hong Ma, Jian Shen, Jinyong Chen, Yidong Wang, Sheng'an Su, Kaijie Chen, Lingxiao Xu, Yao Xie*, Meixiang Xiang*. Piezo1 (Piezo-Type Mechanosensitive Ion Channel Component 1)-Mediated Mechanosensation in Macrophages Impairs Perfusion Recovery After Hindlimb Ischemia in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 2023, 43(4): 504-518.

Chunna Jin, Shiyu Zhu, Tingting Zhao, Jiewen Deng, Meixiang Xiang*, Hong Ma*. Mending a broken heart-targeting cardiomyocyte regeneration: a literature review. Annals of Translational Medicine. 2022, 10(21): 1179.

Xiaoya Wang#, Wudi Li#, Meixiang Xiang*. Increased serum methylmalonic acid levels were associated with the presence of cardiovascular diseases. Frontiers in Cardiovascular Medicine. 2022. 9:966543.

Chengchen Zhao, Chunna Jin, Yimin Shen, Xiaoping Lin, Yi Yu, Meixiang Xiang*. The Prevalence and Characteristics of Mitral Regurgitation in Heart Failure: A Chart Review Study. Reviews in Cardiovascular Medicine. 2022, 23(7): 235.

Yimin Shen#, Guanzhong Chen#, Sheng’an Su, Chenchen Zhao, Hong Ma*, Meixiang Xiang*. Independent Association of Thyroid Dysfunction and Inflammation Predicts Adverse Events in Patients with Heart Failure via Promoting Cell Death. Journal of Cardiovascular Development and Disease. 2022, 9(9): 290.

Jiewen Deng, Yao Xie, Jian Shen, Qing Gao, Jing He, Hong Ma, Yongli Ji, Yong He*, Meixiang Xiang*. Photocurable Hydrogel Substrate—Better Potential Substitute on Bone-Marrow-Derived Dendritic Cells Culturing. Materials. 2022, 15(9): 3322.

Shiyu Zhu#, Chang Liu#, Chengchen Zhao, Guanzhong Chen, Simin Meng, Hong Ma, Meixiang Xiang*, Yao Xie*. Increased Serum Soluble Transferrin Receptor Levels Were Associated With High Prevalence of Cardiovascular Diseases: Insights From the National Health and Nutrition Examination Survey 2017-2018. Frontiers in Cell and Developmental Biology. 2022, 10: 872058. 

Chang Liu#, Yuwen Chen#, Yao Xie*, Meixiang Xiang*. Tubulin Post-translational Modifications: Potential Therapeutic Approaches to Heart Failure. Frontiers in Cell and Developmental Biology. 2022, 10: 874846. 

Hui Ni#, Chang Liu#, Yuwen Chen, Yunrui Lu, Yongli Ji, Meixiang Xiang*, Yao Xie*. MGP Regulates Perivascular Adipose-Derived Stem Cells Differentiation Toward Smooth Muscle Cells Via BMP2/SMAD Pathway Enhancing Neointimal Formation. Cell Transplantation. 2022, 31: 9636897221075747.

Yao Xie#,*, Yongli Ji#, Yunrui Lu#, Yuankun Ma, Hui Ni, Jian Shen, Hong Ma, Chunna Jin, Yuwen Chen, Yan Lin, Meixiang Xiang*. Distinct Characteristics Between Perivascular and Subcutaneous Adipose-Derived Stem Cells. Diabetes. 2022, 71(2):321-328. 

Chengchen Zhao, Chunna Jin, Xiaopeng He, Meixiang Xiang*. The efficacy of trimetazidine in non-ischemic heart failure patients: a meta-analysis of randomized controlled trials. Reviews in cardiovascular medicine. 2021, 22(4): 1451-1459.

Yi Yu, Chunna Jin, Chengchen Zhao, Shiyu Zhu, Simin Meng, Hong Ma, Jian’an Wang*, Meixiang Xiang*. Serum free fatty acids independently predict adverse outcomes in acute heart failure patients. Frontiers in cardiovascular medicine. 2021, 8:761537.

Yuhao Zhang#, Sheng-an Su#, Wudi Li, Yuankun Ma, Jian Shen, Yaping Wang, Yimin Shen, Jian Chen, Yongli Ji, Yao Xie*, Hong Ma*, Meixiang Xiang*. Piezo1-Mediated Mechanotransduction Promotes Cardiac Hypertrophy by Impairing Calcium Homeostasis to Activate Calpain/Calcineurin Signaling. Hypertension. 2021, 78(3):647-660. 

Shufang Zhang#, Xiaofang Huang#, Huiqing Xiu#, Zhongheng Zhang, Kai Zhang, Jiachang Cai, Zhijian Cai, Zhanghui Chen, Zhaocai Zhang, Wei Cui, Gensheng Zhang*, Meixiang Xiang*. The attenuation of Th1 and Th17 responses via autophagy protects against methicillin-resistant Staphylococcus aureus-induced sepsis. Microbes and Infection. 2021, 23(8):104833. 

Yongli Ji#, Yuankun Ma#, Jian Shen#, Hui Ni, Yunrui Lu, Yuhao Zhang, Hong Ma, Chang Liu, Yimin Zhao, Siyin Ding, Meixiang Xiang*, Yao Xie*. TBX20 Contributes to Balancing the Differentiation of Perivascular Adipose-Derived Stem Cells to Vascular Lineages and Neointimal Hyperplasia. Frontiers in Cell and Developmental Biology. 2021, 9: 662704. 

Yuankun Ma#, Liangliang Jia#, Yidong Wang#, Yongli Ji, Jian Chen, Hong Ma, Xiaoping Lin, Yuhao Zhang, Wudi Li, Hui Ni, Lan Xie, Yao Xie*, Meixiang Xiang*. Heme Oxygenase-1 in Macrophages Impairs the Perfusion Recovery After Hindlimb Ischemia by Suppressing Autolysosome-Dependent Degradation of NLRP3. Arteriosclerosis, Thrombosis, and Vascular Biology. 2021, 41(5): 1710-1723. 

Shuo Yu#, Simin Meng, Meixiang Xiang*, Hong Ma*. Phosphoenolppyruvate carboxykinase in cell metabolism: Roles and mechanisms beyond gluconeogenesis. Molecular Metabolism. 2021, 53: 101257.

Yimin Shen#, Yuhao Zhang, Wudi Li, Kaijie Chen, Meixiang Xiang*, Hong Ma*. Glutamine metabolism: From proliferating cells to cardiomyocytes. Metabolism. 2021, 121: 154778. 

Yan Lin#, Siyin Ding#, Yuwen Chen, Meixiang Xiang*, Yao Xie*. Cardiac Adipose Tissue Contributes to Cardiac Repair: a Review. Stem Cell Reviews and Reports. 2021, 17(4): 1137-1153. 

Wudi Li#, Sheng-an Su#, Jian Chen, Hong Ma*, Meixiang Xiang*. Emerging roles of fibroblasts in cardiovascular calcification. Journal of Cellular and Molecular Medicine. 2021, 25(4): 1808-1816. 

Jian Chen, Wudi Li, Meixiang Xiang*. Burden of valvular heart disease, 1990-2017: Results from the Global Burden of Disease Study 2017. Journal of Global Health. 2020;10(2):020404. (Corresponding author)

Jian Shen#, Yongli Ji#, Mingjun Xie#, Haiming Zhao, Wanling Xuan, Li Yin, Xiaohua Yu, Fangfang Xu, Shengan Su, Jing Nie, Yao Xie, Qing Gao, Hong Ma, Xueying Ke, Zhenyu Shi, Jianzhong Fu, Zhenjie Liu*, Yong He*, Meixiang Xiang*. Cell-modified Bioprinted Microspheres for Vascular Regeneration. Materials Science and Engineering: C. 2020, 112:110896. (Co-corresponding author)

Xiaogen Chen#, Chunna Jin#, Lan Xie, Meixiang Xiang*. LCZ696 and Preservation of Renal Function in Heart Failure: A Meta-Analysis of 6 Randomized Trials. Reviews in Cardiovascular Medicine. 2020, 21(1):113-118. (Corresponding author)

Xiaoping Lin#, Yuankun Ma#, Zhejun Cai, Qiyuan Wang, Lihua Wang, Zhaoxia Huo, Dan Hu, Jian’an Wang, Meixiang Xiang*. Next-generation Sequencing Identified Novel Desmoplakin Frame-Shift Variant in Patients With Arrhythmogenic Cardiomyopathy. BMC Cardiovascular Disorders. 2020, 20(1):74. (Corresponding author)

Hui Ni#, Yiming Zhao#, Yongli Ji, Jian Shen, Meixiang Xiang*, Yao Xie*. Adipose-derived stem cells contribute to cardiovascular remodeling. Aging(Albany NY). 2019, 11(23):11756-11769. (Co-corresponding author)

Yidong Wang, Liangliang Jia, Yao Xie, Zhejun Cai, Zhenjie Liu, Jian Shen, Yi Lu, Yaping Wang, Shengan Su, Yuankun Ma, Meixiang Xiang*. Involvement of macrophage-derived exosomes in abdominal aortic aneurysms development. Atherosclerosis. 2019, 289:64-72. 

Yi Lu#, Yidong Wang#, Ting Weng, Zexin Chen, Xiujuan Sun, Jia Wei, Zhejun Cai*, Meixiang Xiang*. Association between metformin use and coronary artery calcification in type2 diabetic patients. Journal of diabetes research. 2019, 2019:9484717. (Co-corresponding author)

Sheng-an Su#, Yao Xie, Yuhao Zhang, Yutao Xi*, Jie Cheng, Meixiang Xiang*. Essential roles of EphrinB2 in mammalian heart: from development to diseases. Cell communication and signaling. 2019, 17(1):29. (Co-corresponding author)

Xiaoya Wang#, Yi Lu, Yao Xie, Jian Shen, Meixiang Xiang*. Emerging roles of proteoglycans in cardiac remodeling. International Journal of Cardiology. 2019, 278:192-198. (Corresponding author)

Zurong Fu#, Fei Li#, Liangliang Jia, Shengan Su, Yaping Wang, Zhejun Cai*, Meixiang Xiang*. Histone deacetylase 6 reduction promotes aortic valve calcification via an endoplasmic reticulum stress-mediated osteogenic pathway. The Journal of Thoracic and Cardiovascular Surgery. 2019, 158(2):408-417. (Co-corresponding author)

Liangliang Jia#, Yaping Wang#, Yidong Wang, Yuankun Ma, Jian Shen, Zurong Fu, Yue Wu, Sheng’an Su, Yuhao Zhang, Zhejun Cai*, Jian’an Wang*, Meixiang Xiang*. Heme oxygenase-1 in macrophages drives septic cardiac dysfunction via suppressing lysosomal degradation of inducible nitric oxide synthase. Circulation  Research. 2018, 122:1532-1544. (Co-corresponding author)

Jian Shen#, Yao Xie#, Zhenjie Liu#, Shuning Zhang, Yaping Wang, Liangliang Jia, Yidong Wang, Zhejun Cai, Hong Ma*, Meixiang Xiang*.Increased myocardial stiffness activates cardiac microvascular endothelial cell via VEGF paracrine signaling in cardiac hypertrophy. Journal of Molecular and Cellular Cardiology. 2018, 122: 140-151. (Co-corresponding author)

Yaping Wang#, Liangliang Jia#, Jian Shen, Yidong Wang, Zurong Fu, Sheng-an Su, Zhejun Cai*, Jian-an Wang, Meixiang Xiang*. Cathepsin B aggravates coxsackievirus B3-induced myocarditis through activating the inflammasome and promoting pyroptosis. Plos Pathogens. 2018, 14(1):e1006872. (Co-corresponding author)

Yan Lin#, Han Chen#, Yidong Wang, Chunna Jin, Xiaoping Lin, Cuncun Wang, Yi Lu, Zexin Chen, Jian-an Wang, Meixiang Xiang*. Association of serum ADAMTs 7 level and genetic variant rs 1994016 with acute coronary syndrome in a chinese population: a case control study. Atherosclerosis 2018, 275:312-318. (Corresponding author)

Yi-dong Wang#, Zhen-jie Liu, Jun Ren, Mei-xiang Xiang*. Pharmacological Therapy of Abdominal Aortic Aneurysm: An Update. Current Vascular Pharmacology. 2018, 16(2):114-124. (Corresponding author)

Yue Wu#, Sheng-an Su, Yao Xie, Jian Shen, Wei Zhu*, Meixiang Xiang*. Murine models of vascular endothelial injury: techniques and pathophysiology. Thrombosis Research, 2018, 169: 64-72. (Co-corresponding author)

Sheng-an Su#, Du Yang#, Yue Wu, Yao Xie, Wei Zhu, Zhejun Cai, Jian Shen, Zurong Fu, Liangliang Jia, Yidong Wang, Yaping Wang, Jian-an Wang, Meixiang Xiang*. EphrinB2 regulates cardiac fibrosis through modulating the interaction of Stat3 and TGF-β/Smad3 signaling. Circulation Research. 2017, 121: 617-627. (Corresponding author)

Zhejun Cai# *, Baoqing Liu#, Jia Wei#, Zurong Fu, Yidong Wang, Yaping Wang, Jian Shen, Liangliang Jia, Shengan Su, Xiaoya Wang, Xiaoping Lin, Han Chen, Fei Li*, Jian'an Wang, Meixiang Xiang*. Deficiency of CCAAT/enhancer-binding protein homologous protein (CHOP) prevents diet-induced aortic valve calcification in vivo. Aging Cell. 2017, 16(6): 1334-1341. (Co-corresponding author)

Yong ZHENG#, Qiang GU#, Hong-wu CHEN, Huai-ming PENG, Dong-yu JIA, Yu ZHOU, Mei-xiang XIANG*. Efficacy of amiodarone and lidocaine for preventing ventricular fibrillation after aortic cross-clamp release in open heart surgery: a meta-analysis of randomized controlled trials. J Zhejiang Univ Sci B. 2017;18(12):1113-1122. (Corresponding author)

Sheng-an Su, Du Yang, Wei Zhu，Zhejun Cai, Na Zhang, Lina Zhao, Jian-an Wang, Meixiang Xiang*. Interleulin-17A mediates cardioyocyte apoptosis through Stat3-iNOS pathway. BBA-Molecular Cell Research. 2016, 11:2784-2794. (Corresponding author)

Yi Lu, Yi-dong Wang, Xiao-ya Wang, Han Chen, Zhe-jun Cai, Mei-xiang Xiang*. SIRT3 in cardiovascular diseases: Emerging roles and therapeutic implications. International Journal of Cardiology. 2016, 220:700-705. (Corresponding author)

Du Yang, Chunna Jin, Hong Ma, Mingyuan Huang, Guo-ping Shi, Jianan Wang, Meixiang Xiang*. EphrinB2/EphB4 pathway in postnatal angiogenesis: a potential therapeutic target for ischemic cardiovascular disease. Angiogenesis. 2016, 19(3): 297-309. (Corresponding author)

Ya-ping Wang , Yao Xie, Hong Ma, Sheng-an Su, Yi-dong Wang, Jian-an Wang, Mei-xiang Xiang*. Regulatory T lymphocytes in myocardial infarction: A promising new therapeutic target. International Journal of Cardiology. 2016, 203:923-928. (Corresponding author)

Zhejun Cai, Li Shen, Hong Ma, Jin Yang, Du Yang, Han Chen, Jia Wei, Qiulun Lu, Dao Wen Wang, Meixiang Xiang*, Jian'an Wang*. Involvement of Endoplasmic Reticulum Stress-Mediated C/EBP Homologous Protein Activation in Coxsackievirus B3-Induced Acute Viral Myocarditis. Circulation Heart failure. 2015, 8(4): 809-818. (Co-corresponding author)

Bu-yun Xu, Mei-xiang Xiang*, Jian-an Wang. Endothelail Progenitor Cell and In-Stent Restenosis. Current Stem Cell Research & Therapy. 2015, 10(4): 364-71. (Corresponding author)

Mingyuan Huang, Du Yang, Meixiang Xiang*, Jianan Wang . Role of interleukin-6 in regulation of immune responses to remodeling after myocardial infarction. Heart Failure Reviews. 2015, 20(1): 25-38. (Corresponding author)

Zhi-Yu Wang, Meng Chen, Ling-Ling Zhu, Lu-Shan Ya, Su Zeng, Mei-Xiang Xiang*, Quan Zhou*. Pharmacokinetic drug interactions with clopidogrel: updated review and risk management in combination therapy. Therapeutics and Clinical risk management. 2015.11: 449-467 (Co-corresponding author)

Jing Wang, Jes S Lindholt, Galina K Sukhova, Michael A Shi, Mingcan Xia, Han Chen, Meixiang Xiang, Aina He, Yi Wang, Na Xiong, Peter Libby, Jian-An Wang, Guo-Ping Shi. IgE actions on CD4+ T cells, mast cells, and macrophages participate in the pathogenesis of experimental abdominal aortic aneurysms. EMBO Molecular Medicine. 2014, 6(7): 952-69. 

Mingyuan Huang, Lihan Wang, Hong Ma, JiananWang, Meixiang Xiang*. Lack of an association between interleukin-6 -174G/C polymorphism and circulating interleukin-6 levels in normal population: a meta-analysis. DNA Cell Biology. 2013, 32(11): 654-64.  (Corresponding author)

Sheng-an Su, Hong Ma, Li Shen, Mei-xiang Xiang*, Jian-an Wang. Interleukin-17 and acute coronary syndrome. Journal of Zhejiang University-Science B. 2013, 14(8): 664-669.(Corresponding author)

Li Shen, Hong Ma, Mei-Xiang Xiang*, Jian-An Wang*. Meta-analysis of cohort studies of baseline prehypertension and risk of coronary heart disease. American Journal of Cardiology. 2013, 15: 112(2): 266-271. (Co-corresponding author)

Han Chen, Jing Wang, Mei-Xiang Xiang, Yan Lin, Aina He, Chun-Na Jin, Jian Guan, Galina K. Sukhova, Peter Libby, Jian-An Wang, Guo-Ping Shi. Cathepsin S-mediated fibroblast trans-differentiation contributes to left ventricular remodelling after myocardial infarction. Cardiovascular Research. 2013, 100(1): 84-94. 

Li SHEN, Liu-guang Song, Hong MA, Chun-na JIN, Jian-an WANG, Mei-xiang XIANG*. Tea consumption and risk of stroke: a dose-response meta-analysis of prospective studies. Journal of Zhejiang University-Science B. 2012, 13(8): 652-62. (Corresponding author)

Chun-na JIN, Hong MA, Ya LIN, Jian-an WANG, Mei-xiang XIANG*. Association between SNP rs1800875, serum chymase and immunoglobulin E levels in patients with coronary heart disease. Journal of Zhejiang University-Science B. 2011, 12(8): 660-667. (Corresponding author)

Jing Wang#, Xiang Cheng#, Mei-xiang Xiang #, Mervi Alanne-Kinnunen, Jian-an Wang, Han Chen, Aina He, Xinghui Sun, Yan Lin, Ting-Ting Tang, Xin Tu,  Sara Sjoeberg, Galina K. Sukhova, Yu-Hua Liao, Daniel H.Conrad, Lunyin Yu, Toshiaki Kawakami, Petri T. Kovanen, Peter Libby, Guo-Ping Shi. IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe(-/-) mice. Journal of Clinical Investigation. 2011, 121(9):3564-3577. (Co-first author)

Meixiang Xiang#, Jiusong Sun, Yan Lin, Jie Zhang, Han Chen, Dan Yang , Jian-an Wang, Guo-ping Shi. Usefulness of serum tryptase level as an independent biomarker for coronary plaque instability in a Chinese population. Atherosclerosis. 2011, 215(2): 494-499. 

Jiusong Sun, Galina K. Sukhova, Jie Zhang, Han Chen, Sara Sjöberg, Peter Libby, Meixiang Xiang, Jianan Wang, Christoph Peters, Thomas Reinheckel, Guo-Ping Shi. Cathepsin L activity is essential to elastase perfusion-induced abdominal aortic aneurysms in mice. Arteriosclerosis Thrombsis and Vascular Biology. 2011, 31(11): 2500-8. 

Xiao-Hong Pan, Song-Zhao Zhang, Hui-Qiang Chen, Mei-Xiang Xiang, Jian-An Wang. Spuriously High B-Type Natriuretic Peptide Level Caused by Human Antimouse Antibodies. Annals of Internal Medicine. 2011, 155(6): 407-8.

Shu-qin YING, Mei-xiang XIANG*, Lu FANG , Jian-an WANG. Temporal changes in circulating P-select, plasminogen activator inhibitor, magnesium, and creatine kinase after percutaneous coronary intervention. Journal of Zhejiang University-Science B. 2010, 11(8): 575-82. (Corrsponding author)

PAN Xiao-hong, ZHONG Wen-zhao, XIANG Mei-xiang*, XU Geng, SHAN Jiang, WANG Jian-an. Clinical outcomes of serolimus-eluting stents versus bare metal stents in ST-segment elevation myocardial infarction patients: a meta-analysis. Chinese Medical Journal. 2009, 122(1): 88-92. (Corresponding author)

Mei-xiang XIANG#, Ai-na HE, Jian-an WANG, Chun GUI. Protective paracrine effect of mesenchymal stem cells on cardiomyocytes. Journal of Zhejiang University-Science B (Biomedicine & Biotechnology). 2009, 10(8): 619-624. 

Meixiang Xiang#, Jianan Wang, Emel Kaplan, Peter Oettgen, Lewis Lipsitz , James P. Morgan, Jiang-yong Min. Antiapoptotic effect of implanted embryonic stem cell-derived early-differentiated cells in aging rats after myocardial infarction. Journals of Gerontology Series A-Biological Sciences and Medical Sciences. 2006, 61(12): 1219-1227.