Position：Vice President of SAHZU Binjiang Campus
Department：Nuclear Medicine and PET-CT Center
Medical School：Gunma University School of Medicine, JAPAN
Development of nuclear medicine and molecular imaging approaches to monitor fundamental cellular or molecular events in living subjects.
Stem cell imaging using multimodality imaging technologies positron emission tomography (PET), optical imaging, magnetic resonance imaging, etc.
Nuclear medicine and molecular imaging applications in the fields of neuroscience and brain-computer interface.
Award for Technological Advancement of Higher Educational Institution, First Prize, 2018
Innovative Collaboration Award of China Industry-University-Research Collaboration Association, First Prize, 2019
L'Oréal-UNESCO For Women in Science China, 2017
Medicine Prize of Academician Shusen Lanjuan Talent Foundation, 2017
Science and Technology Award for Chinese Youth, 2016
Chair, The World Molecular Imaging Society, 2020-present
Editorial Consultant, Lancet, 2005−present
Editorial Board Member, Oncology, Karger, 2005−present
Associate Editor, European Journal of Nuclear Medicine and Molecular Imaging, 2006−present
Associate Editor, Journal of Nuclear Medicine, 2007−present
Editorial Board Member, Nuclear Medicine Communications, 2010−present
Associate Editor, Annals of Nuclear Medicine, 2013−present
Regional Editor, Molecular Imaging and Biology, 2015-present
Board Member, World Molecular Imaging Society, 2016-present
Honorary Professor, Hong Kong Polytechnic University, Hong Kong
Prof. Tian's group focuses on molecular imaging with a particular emphasis on human major diseases. Her current research interests include molecular imaging of central nerve system (CNS) diseases & psychiatric disorders, imaging-based stem cell therapy for stroke, development of novel imaging strategies for a better understanding of underlying mechanism of brain. Her team has developed precision PET imaging approach on pediatric epilepsy and MRI-negative pre-operative epilepsy. Furthermore, Prof. Tian's group has extended their research on brain-machine interface (BMI), internet gaming disorder (IGD), post-traumatic stress disorder (PTSD), etc., and continually to develop big data-based smart diagnosis for neuro-psychiatric disorders, including AD, PD and others. Her group also develops novel molecular imaging agents or smart probes for precision theranostics.
Cai X, Zhang K, Xie X, Zhu X, Feng J, Jin Z, Zhang H, Tian M*, Chen H*. Self-assembly hollow manganese Prussian white nanocapsules attenuate Tau-related neuropathology and cognitive decline. Biomaterials, 2020 Feb;231:119678.
Du R, Zhu X, Wu S, Zhang X, He Y, Zhang K, He X, Wang X, Sun Y, Wang Q, Zhang H*, Tian M*. PET imaging of metabolic changes after neural stem cells and GABA progenitor cells transplantation in a rat model of temporal lobe epilepsy. Eur J Nucl Med Mol Imaging. 2019 Oct;46(11):2392-2397.
He X, Jin C, Ma M, Zhou R, Wu S, Huang H, Li Y, Chen Q, Zhang M, Zhang H*, Tian M*. PET imaging on neurofunctional changes after optogenetic stimulation in a rat model of panic disorder. Front Med. 2019 Oct;13(5):602-609.
Zhang K, Tu M, Gao W, Cai X*, Song F, Chen Z, Zhang Q, Wang J, Jin C, Shi J, Yang X, Zhu Y, Gu W, Hu B, Zheng Y*, Zhang H*, Tian M*. Hollow Prussian Blue Nanozymes Drive Neuroprotection against Ischemic Stroke via Attenuating Oxidative Stress, Counteracting Inflammation, and Suppressing Cell Apoptosis. Nano Lett. 2019 May 8;19(5):2812-2823.
Ji J, Ma F, Zhang H, Liu F, He J, Li W, Xie T, Zhong D, Zhang T, Tian M*, Zhang H*, Santos H*, Zhou M*. Light-Activatable Assembled Nanoparticles to Improve Tumor Penetration and Eradicate Metastasis in Triple Negative Breast Cancer . Advanced Functional Materials. 2018, 28(33):1-14.
Chen Q, Du Y, Zhang K, Liang Z, Li J, Yu H, Ren R, Feng J, Jin Z, Li F, Sun J, Zhou M, He Q, Sun X, Zhang H, Tian M*, Ling D*. Tau-Targeted Multifunctional Nanocomposite for Combinational Therapy of Alzheimer's Disease. ACS Nano. 2018 Feb 27;12(2):1321-1338.
Ding Y, Zhu Y, Jiang B, Zhou Y, Jin B, Hou H, Wu S, Zhu J, Wang ZI, Wong CH, Ding M, Zhang H, Wang S, Tian M*. 18F-FDG PET and high-resolution MRI co-registration for pre-surgical evaluation of patients with conventional MRI-negative refractory extra-temporal lobe epilepsy. Eur J Nucl Med Mol Imaging. 2018 Jul;45(9):1567-1572.
Chen Y, Wang L, Liu H, Song F, Xu C, Zhang K, Chen Q, Wu S, Zhu Y, Dong Y, Zhou M, Zhang H, Tian M*. PET Imaging on Dynamic Metabolic Changes after Combination Therapy of Paclitaxel and the Traditional Chinese Medicine in Breast Cancer-Bearing Mice. Mol Imaging Biol. 2018 Apr;20(2):309-317.
Wei Q, Chen Y, Ma X, Ji J, Qiao Y, Zhou B, Ma F, Ling D, Zhang H, Tian M*, Tian J*, Zhou M*. High-Efficient Clearable Nanoparticles for Multi-Modal Imaging and Images-Guided Cancer Therapy. Advanced Functional Materials. 2018 Jan 10,28(2):1704634.
Zhu Y, Feng J, Ji J, Hou H, Chen L, Wu S, Liu Q, Yao Q, Du P, Zhang K, Chen Q, Chen Z, Zhang H, Tian M*. Alteration of monoamine receptor activity and glucose metabolism in paediatric patients with anticonvulsant-induced cognitive impairment. J Nucl Med. 2017 Sep;58(9):1490-1497.
Zhu Y, Feng J, Wu S, Hou H, Ji J, Zhang K, Chen Q, Chen L, Cheng H, Gao L, Chen Z, Zhang H, Tian M*. Glucose Metabolic Profile by Visual Assessment Combined with Statistical Parametric Mapping Analysis in Pediatric Patients with Epilepsy. J Nucl Med. 2017 Aug;58(8):1293-1299.
Chen Q, Zhang Y, Hou H, Du F, Wu S, Chen L, Shen Y, Chao F, Chung JK, Zhang H, Tian M*. Neural correlates of the popular music phenomenon: evidence from functional MRI and PET imaging. Eur J Nucl Med Mol Imaging. 2017 Jun;44(6):1033-1041.
Zhang R, Cheng K, Antaris AL, Ma X, Yang M, Ramakrishnan S, Liu G, Lu A, Dai H, Tian M*, Cheng Z*. Hybrid anisotropic nanostructures for dual-modal cancer imaging and image-guided chemo-thermo therapies. Biomaterials. 2016 Oct;103:265-277.
Wu S, Liu H, Du R, Chen Y, Xu C, Shen Y, Zhang S, Song F, Zhang K, Zhu Y, Wang Z, Gu W,Ignasi Carrió, Tatsuya Hayashi, Yasuyoshi Watanabe, Zhang H, Tian M*. In vivo Dynamic Metabolic Changes after Induced Pluripotent Stem Cells for Ischemia Injury, J Nucl Med. 2016 Dec;57(12):2012-2015.
Zhu Y, Xu K, Xu C, Zhang J, Ji J, Zheng X, Zhang H, Tian M*. PET Mapping for Brain-Computer-Interface-Based Stimulation in a Rat Model with Intracranial Electrode Implantation in the Ventro-posterior Medial Thalamus. J Nucl Med. 2016 Jul;57(7):1141-1145.
Zhu Y, Du R, Zhu Y, Shen Y, Zhang K, Chen Y, Song F, Wu S, Zhang H, Tian M*.PET mapping of neurofunctional changes in a post-traumatic stress disorder model. J Nucl Med. 2016 Sep;57(9):1474-1477.
Zhang K, Zhu Y, Zhu Y, Wu S, Liu H, Zhang W, Xu C, Zhang H, Hayashi T*, Tian M*. Molecular, Functional, and Structural Imaging of Major Depressive Disorder. Neurosci Bull. 2016 Jun;32(3):273-285.
Zhang H, Song F, Xu C, Liu H, Wang Z, Li J,WuS, Shen Y, Chen Y, Zhu Y, Du R, Tian M*. Spatiotemporal PET imaging of dynamic metabolic changes after combined therapeutic approach of induced pluripotent stem cells (iPSCs), neuronal stem cells (NSCs) and Chinese patent medicine in a rat model of cerebral ischemic-reperfusion injury. J Nucl Med. 2015 Nov;56(11):1774-1779.