Position: Vice Chair of Respiratory Medicine
Department：Respiratory Medicine
Medical School：Zhejiang University School of Medicine, China
Academic Rank：Associate Chief Physician
Pulmonary infection, lung cancer, and asthma.
Member, Infection Group, Respiratory Disease Society, Chinese Medical Association, 2017-present
Standing Committee Member, Respiratory Medicine Society, Zhejiang Medical Association, 2019-present
Han Yinglin; Chen lin; Liu huiwen; Jin Zhangchu; Wu Yinfang; Wu Yanping; Li Wen; Ying Songmin; Chen Zhihua; Shen Huahao; Yan Fugui*. Airway epithelial cGAS is critical for induction of experimental allergic airway inflammation, Journal of Immunology, 2020, 204(6):1437-1447.
Yan, Fugui, Wu, Yinfang; Liu, Huiwen; Wu, Yanping; Shen, Huahao; Li, Wen*; ATF3 is positively involved in particulate matter-induced airway inflammation in vitro (vol 287, pg 113, 2018), Toxicology Letters, 2019, 300: 116-117.
Yan, Fugui, Xiao, Yan; Li, Mingkun; Zhang, Hao; Zhang, Rong; Zhou, Hongwei; Shen, Huahao; Wang, Jianwei; Li, Wen*; Ren, Lili*; Metagenomic Analysis Identified Human Rhinovirus B91 Infection in an Adult Suffering from Severe Pneumonia, American Journal of Respiratory and Critical Care Medicine, 2017, 195(11): 1535-1536.
Yan Fugui, Li Wen; Zhou Hongbin; Wu Yinfang; Ying Songmin; Chen Zhihua; Shen Huahao*; Interleukin-13-induced MUC5AC expression is regulated by a PI3K-NFAT3 pathway in mouse tracheal epithelial cells , Biochemical and Biophysical Research Communications, 2014, 446(1): 49-53.
Yan Fugui, Chen C, Jing J,Li W, Shen H, Wang X*. Association between polymorphism of glutathione S-transferase P1 and chronic obstructive pulmonary disease: A meta-analysis. Respir Med. 2010,104(4):473-80.
Yan Fugui, Li W, Jono H, Li Q, Zhang S, Li JD, Shen H*. Reactive oxygen species regulate Pseudomonas aeruginosa Lipopolysaccharide-induced MUC 5AC mucin expression via PKC-NADPH oxidase-ROS-TGF-alphasignaling pathways in human airway epithelial cells. BBRC. 2008, 366(2):513-9.
The role of cGAS-STING signaling pathway in the pathogenesis of asthma and its mechanism. Funding Source: National Natural Science Foundation of China.
The role and mechanism of Cnb1/Nfatc3 signaling pathway in IL-13-mediated airway MUC5AC synthesis in asthma. Funding Source: National Natural Science Foundation of China.
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