Yan Fugui, M.D., Ph.D.

Position:  Vice Chair of Respiratory Medicine

Department:Respiratory Medicine

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Associate Chief Physician


Clinical / Research Interests

Pulmonary infection, lung cancer, and asthma.

Professional Highlights

Professional Appointments

Member, Infection Group, Respiratory Disease Society, Chinese Medical Association, 2017-present

Standing Committee Member, Respiratory Medicine Society, Zhejiang Medical Association, 2019-present

Education Experience

Research Summary


Han Yinglin; Chen lin; Liu huiwen; Jin Zhangchu; Wu Yinfang; Wu Yanping; Li Wen; Ying Songmin; Chen Zhihua; Shen Huahao; Yan Fugui*. Airway epithelial cGAS is critical for induction of experimental allergic airway inflammation, Journal of Immunology, 2020, 204(6):1437-1447. 

Yan, Fugui, Wu, Yinfang; Liu, Huiwen; Wu, Yanping; Shen, Huahao; Li, Wen*; ATF3 is positively involved in particulate matter-induced airway inflammation in vitro (vol 287, pg 113, 2018), Toxicology Letters, 2019, 300: 116-117.

Yan, Fugui, Xiao, Yan; Li, Mingkun; Zhang, Hao; Zhang, Rong; Zhou, Hongwei; Shen, Huahao; Wang, Jianwei; Li, Wen*; Ren, Lili*; Metagenomic Analysis Identified Human Rhinovirus B91 Infection in an Adult Suffering from Severe Pneumonia, American Journal of Respiratory and Critical Care Medicine, 2017, 195(11): 1535-1536.

Yan Fugui, Li Wen; Zhou Hongbin; Wu Yinfang; Ying Songmin; Chen Zhihua; Shen Huahao*; Interleukin-13-induced MUC5AC expression is regulated by a PI3K-NFAT3 pathway in mouse tracheal epithelial cells , Biochemical and Biophysical Research Communications, 2014, 446(1): 49-53. 

Yan Fugui, Chen C, Jing J,Li W, Shen H, Wang X*. Association between polymorphism of glutathione S-transferase P1 and chronic obstructive pulmonary disease: A meta-analysis. Respir Med. 2010,104(4):473-80. 

Yan Fugui, Li W, Jono H, Li Q, Zhang S, Li JD, Shen H*. Reactive oxygen species regulate   Pseudomonas aeruginosa Lipopolysaccharide-induced MUC 5AC mucin expression via PKC-NADPH oxidase-ROS-TGF-alphasignaling pathways in human airway epithelial cells. BBRC. 2008, 366(2):513-9.

Current Program

The role of cGAS-STING signaling pathway in the pathogenesis of asthma and its mechanism. Funding Source: National Natural Science Foundation of China.

The role and mechanism of Cnb1/Nfatc3 signaling pathway in IL-13-mediated airway MUC5AC synthesis in asthma. Funding Source: National Natural Science Foundation of China.

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