Lei Lihong, M.D., Ph.D.

Department: Oral Medicine 

Medical School: Zhejiang University School of Medicine, China

Academic Rank: Associate Chief Physician


Appointment

Clinical / Research Interests

Comprehensive treatment of periodontal diseases, especially tooth retention for severe periodontitis; implant therapy for patients with periodontitis; combination of multiple techniques (e.g., CGF, APRF/IPRF, GTR) for alveolar bone defect and gingival recession repair.

Professional Highlights

Zhejiang Scientific and Technological Progress Award, Third Prize, 2014

Quality Teaching Award, Zhejiang University, Second Prize, 2016

Teaching Innovation of Periodontology, National Utility Model Patent (No. CN201420467470.4) 

Professional Appointments

Youth Committee Member, Society of Periodontology, Chinese Stomatological Association

Secretary, Society of Periodontology, Zhejiang Stomatological Association

Education Experience

Research Summary

Publications

Lei Lihong, Yu Yuanyuan, Han Jiayin, et al. Quantification of growth factors in advanced platelet-rich fibrin and concentrated growth factors and their clinical efficiency as adjunctive to the GTR procedure in periodontal intrabony defects. J Periodontol, 2019: 10.1002/JPER.1019-0290.

Lei Lihong, Yu Yuanyuan, Ke Ting, et al. The Application of Three-Dimensional Printing Model and Platelet-Rich Fibrin Technology in Guided Tissue Regeneration Surgery for Severe Bone Defects. J Oral Implantol, 2019, 45(1): 35-43.

Tan Jingyi, Lei Lihong, Chen Xiaotao, et al. AKT2 is involved in the IL-17A-mediated promotion of differentiation and calcification of murine preosteoblastic MC3T3-E1 cells. Molecular Medicine Reports, 2017, 16(5): 5833-5840.

Xiao-Tao Chen, Li-Li Chen, Jing-Yi Tan, Dan-Hui Shi, Ting Ke, Li-Hong Lei (corresponding author). Th17 and Th1 Lymphocytes Are Correlated with Chronic Periodontitis,Immunological Investigations, 2016, 45(3): 243-254.

Current Program

Research on new techniques for diagnosis and treatment of ENT and oral diseases - Development and application of novel complex for periodontal tissue regeneration. Funding Source: Key Research and Development Foundation, Zhejiang Provincial Department of Science and Technology, 2019-2022.

Cascade interactions between autophagy-related protein and IL-17 persistently activating the signaling pathway of alveolar bone destruction. Funding Source: National Natural Science Foundation of China, 2018-2021.

3D-printed customized module for alveolar bone defect repair to induce periodontal tissue regeneration (PI). Funding Source: Zhejiang Province Welfare Technology Applied Research Foundation, 2017-2019.

Mechanism of autophagy-related molecule p62 regulating alveolar bone resorption through the Wnt signaling pathway. Funding Source: Natural Science Foundation of Zhejiang, 2016-2018.

Research and development of simulated periodontal surgery model and progressive teaching methods to promote the clinical application of the experimental curriculum periodontology (PI). Funding Source: Curriculum Reform in Higher Education Foundation, Zhejiang Provincial Department of Education, 2015-2017.

Research on the effects of different Th17 phenotypes and characteristic secretory factors on alveolar bone destruction. Funding Source: National Natural Science Foundation of China, 2013-2016.

Research on individual susceptibility to periodontitis mediated by the functional axis of IL-17 characteristically produced by Th17 cells. Funding Source: Natural Science Foundation of Zhejiang, 2012.-2014.

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