Ding Yuan, M.D.

Position: Assistant to Hospital President

Vice President of Chengdong Campus, SAHZU

Vice Chair of HPB Surgery

Medical School:Zhejiang University School of Medicine, China  

Academic Rank:Associate Chief Physician

Appointment

Clinical / Research Interests

Surgery and comprehensive therapy of hepatobiliary and pancreatic disease and transplantation, especially in the precise diagnosis and treatment of complicated hepatobiliary and pancreatic tumors

Artificial intelligence in medicine

Liver transplantation, including living donor liver transplantation for children

Professional Highlights

National High-Level Talents Special Support Program

High-Level Talents Special Support Program of Zhejiang Provience

Medical New Star of Zhejiang Province

First Prize, Zhejiang Science and Technology Advancement Prize

Clinical Top-notch Young Talent, Zhejiang University School of Medicine

Professional Appointments

Vice Chairman, Youth Committee of Surgery Branch, Zhejiang Medical Association

Vice Chairman, Medical Artificial Intelligence Expert Committee, Chinese Hospital Association

Member, Surgical Oncology Committee, Zhejiang Medical Association

Vice Chairman and Secretary General, Youth Committee of Enhanced Recovery After Surgery Branch, Zhejiang Medical Association

Chairman, Youth Committee of Integrated Oncology Expert Committee, Zhejiang Anti-Cancer Association

Member, Chinese Holistic Integrative Oncology (CHIO), Traditional Chinese and Western Medince Association

Member, Organ Acquisition and Allocation Committee, Chinese Hospital Association

Secretary General, Youth Committee of Enhanced Recovery After Surgery Expert Committee of Surgeons Branch, Chinese Medical Doctor Association

Member and Secretary General, Organ Transplantation Group of Expert Committee of Enhanced Recovery After Surgery, National Health Commission

Secretary, Enhanced Recovery After Surgery Branch, Zhejiang Medical Association

Secretary, Specialist Committee on Enhanced Recovery After Surgery, National Health Council

Member, Enhanced Recovery After Surgery Expert Committee, Chinese Medical Education Association

Member, Expert Committee of Hepatobiliary and Pancreatic MDT, International Hepatobiliary and Pancreatic Society, China Branch

Member, Zhejiang Branch of China Hepatobiliary and Pancreatic Alliance

Member, Youth Committee of Smart Medical Committee, Chinese Medical Doctor Association

Member, Youth Group of Hepatobiliary and Pancreatic Surgery Professional Committee, Cross-Strait Medical and Health Exchange Association

Editorial board member, Journal of Clinical and Translational Hepatology

Editorial board member, Journal of Pancreatology

Editorial board member, Chinese Journal of Hepatobiliary and Pancreatic Surgery

Education Experience

Research Summary

Publications

Yang Dua, Xiaohui Qiana, Fenghao Ling, Bingqiang Gao,Weili Wanga, Huang Yangg,?Weilin Wang*,Yuan Ding*. A biomimetic nanoplatform for precise reprogramming of tumor-associated macrophages and NIR-II mediated antitumor immune activation10fen datongxun.Acta Biomaterialia. 2023 Mar 20: S1742-7061(23)00157-5. (IF 10.633)

Jiaojiao Zhang, Bingqiang Gao, Binglin Ye, Zhongquan Sun, Zhefeng Qian, Lisha Yu, Yanli Bi, Lie Ma, Yuan Ding,* Yang Du,* Weilin Wang,* and Zhengwei Mao*. Mitochondrial-Targeted Delivery of Polyphenol-Mediated Antioxidases Complexes against Pyroptosis and Inflammatory Diseases.Adv Mater. 2023 Jan 17: e2208571. (IF 32.086)

Ding Y # , Tong Z # , Jin L # , Ye B, Zhou J * , Sun Z, Yang H, Hong L, Huang F, Wang W * , Mao Z * . An NIR Discrete Metallacycle Constructed from Perylene Bisimide and Tetraphenylethylene Fluorophores for Imaging-Guided Cancer Radio-Chemotherapy. Adv Mater. 2022 Feb;34(7):e2106388. (IF 32.086)

Tong Z # , Guo Q, Xu G, Gao Y,Yang H, Ding Y*, Wang W*, Mao Z*,Supramolecular hydrogel-loaded Prussian blue nanoparticles with photothermal and ROS scavenging ability for tumor postoperative treatments,Composites Part B: Engineering, 2022 (IF 11.322)

Yang H # , Ding Y # , Tong Z, Qian X, Xu H, Lin F, Sheng G * , Hong L, Wang W * , Mao Z * . pH-responsive hybrid platelet membrane-coated nanobomb with deep tumor penetration ability and enhanced cancer thermal/chemodynamic therapy. Theranostics. 2022 May 16;12(9):4250-4268. (IF 11.6)

Ding Y # , Sun Z # , Gao Y # , Zhang S # , Yang C, Qian Z, Jin L, Zhang J, Zeng C, Mao Z * , Wang W * . Plasmon-Driven Catalytic Chemotherapy Augments Cancer Immunotherapy through Induction of Immunogenic Cell Death and Blockage of IDO Pathway. Adv Mater. 2021 Aug;33(34):e2102188. (IF 32.086)

Ding Y # , Xu H # , Xu C # , Tong Z # , Zhang S, Bai Y, Chen Y, Xu Q, Zhou L, Ding H, Sun Z, Yan S * , Mao Z * , Wang W * . A Nanomedicine Fabricated from Gold Nanoparticles-Decorated Metal-Organic Framework for Cascade Chemo/Chemodynamic Cancer Therapy. Adv Sci (Weinh). 2020 Jun 14;7(17):2001060. (IF 17.521)

Ding Y # , Sun Z # , Tong Z # , Zhang S, Min J, Xu Q, Zhou L, Mao Z * , Xia H * , Wang W * . Tumor microenvironment-responsive multifunctional peptide coated ultrasmall gold nanoparticles and their application in cancer radiotherapy. Theranostics. 2020 Apr 6;10(12):5195-5208. (IF 11.6 )

Ding Y # , Zhang S # , Sun Z # , Tong Z # , Ge Y, Zhou L, Xu Q, Zhou H * , Wang W * . Preclinical validation of silibinin/albumin nanoparticles as an applicable system against acute liver injury. Acta Biomater. 2022 Jul 1;146:385-395. (IF: 10.633)

Yang Y # , Ding Y # , Fan B, Wang Y, Mao Z * , Wang W * , Wu J * . Inflammation-targeting polymeric nanoparticles deliver sparfloxacin and tacrolimus for combating acute lung sepsis. J Control Release. 2020 May 10;321:463-474. (IF: 11.467)


Current Program

The mechanism and intervention research of NEK2-dependent MDSC metabolic reprogramming and mitochondrial homeostasis regulation in immune escape of liver cancer NEK2, 82272860, General Program of National Natural Science Foundation of China

Study on the mechanism of hepatocyte chemotactic MDSC against ischemia reperfusion injury through YAP-CCL15 pathway, 82001673, National Natural Science Foundation of China

Study on the application of preoperative education system based on mobile streaming media platform in ERAS, Y201840044, scientific research project, Department of Education of Zhejiang Province

The role and mechanism of the comprehensive immune therapy system based on the DC vaccine for HCC in the recurrence of HCC after anti-liver transplantation, 2016KYB083, Medical Health Science and Technology Project, Zhejiang Provincial Health Commission

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