Du Linlin, M.D., Ph.D.

Department:Intensive Care Unit

Medical School:Sun Yat-sen University, China

Academic Rank:Associate Chief Physician


Clinical / Research Interests

Severe pneumonia, shock, respiratory failure, sepsis, heart failure, multiple organ dysfunction syndrome, malnutrition due to critical illness.

Professional Highlights

Professional Appointments

Youth Committee Member, Zhejiang Society for Critical Care Medicine

Education Experience

Research Summary


Xu Y, Zhang S, Rong J, Lin Y, Du L, Wang Y*, Zhang Z*. Sirt3 is a novel target to treat sepsis induced myocardial dysfunction by acetylated modulation of critical enzymes within cardiac tricarboxylic acid cycle [published online ahead of print, 2020 Jun 8]. Pharmacol Res. 2020;159:104887. doi:10.1016/j.phrs.2020.104887.

Yang H, Du L, Zhang Z*. Potential biomarkers in septic shock besides lactate [published online ahead of print, 2020 Apr 10]. Exp Biol Med (Maywood). 2020;1535370220919076. doi:10.1177/1535370220919076.

Wei, Haiyan; Fu, Peifen; Yao, Minya; Chen, Yaomin; Du, Linlin *. Breast cancer stem cells phenotype and plasma cell-predominant breast cancer independently indicate poor survival. PATHOLOGY RESEARCH AND PRACTICE, 2016 : 294~301212 (4).

Du L, Tang H, Ma Z, Xu J, Gao W, Chen J, Gan W, Zhang Z, Yu X, Zhou X, Hu X. The protective effect of the recombinant 53-kDa protein of Trichinella spiralis on experimental colitis in mice.  Dig Dis Sci. 2011 Oct; 56(10):2810-7. Zhang San; Li Si, Wang Wu, et al. Frequency of extrapancreatic neoplasms in intraductal papillary mucinous neoplasm of the pancreas: implications for management. Annals of Surgery, 2015,250(12): 31-35.

Du L*, Liu L, Yu Y, Shan H, Li L.Trichinella spiralis Excretory-Secretory Products Protect against Polymicrobial Sepsis by Suppressing MyD88 via Mannose Receptor. Biomed Res Int. 2014; 2014: 898646. 

Du L*, Wei H, Li L, Shan H, Yu Y, Wang Y, Zhang G. Regulation of recombinant Trichinella spiralis 53-kDa protein (rTsP53) on alternatively activated macrophages via STAT6 but not IL-4Rα in vitro. Cell Immunol. 2014, Mar-Apr; 288(1-2):1-7. 

Current Program

The changes of malate-asparate shuttle in mitochondrial energy metabolism in septic cardiomyopathy based on Sirt3 knockout mice. Funding Source: Natural Science Foundation of Zhejiang (LGD20H150003), 2020-2022.

The effect of Trichinella spiralis 53-kDa protein on macrophage phenotype. Funding Source: National Natural Science Foundation of China (81202322), 2013-2015.

Find People

Search by Family Name

Find A Department

Search by Departments