Department:Medical Oncology
Medical School:Zhejiang University School of Medicine, China
Academic Rank:Associate Chief Physician
Personalized and comprehensive therapy of gastrointestinal cancer and lung cancer with chemotherapy, targeted therapy and immunotherapy.
Zhejiang Medicine and Health Innovation Award, Third Prize, 2015
Member, Chemotherapy Committee, Zhejiang Anti-Cancer Association, 2015-present
Member, Anti-Cancer Drug Committee, Zhejiang Anti-Cancer Association, 2015-present
Molecular mechanisms of cancer metastasis.
Chen C, Ge J, Lu Q, Ping G, Yang C, Fang X. Expression of Lysine-specific demethylase 1 in human epithelial ovarian cancer, J Ovarian Res, 2015, 8(28).
Hou Z, Xu C, Xie H, Xu H, Zhan P, Yu L, Fang X. Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients, PLoS One, 2014, 9(9): e108133.
Xuefeng Fang, Zhibo Hou, Xinzheng Dai, Cong Chen, Jing Ge, Hong Shen, Xiaofeng Li, Like Yu, Ying Yuan. SATB1 is overexpressed in colorectal cancer and promotes colorectal cancer cell growth and metastasis. World J Gastroenterol. 2013 Apr 21;19(15):2331-9.
Hou Z, Yin H, Chen C, Dai X, Li X, Liu B, Fang X. MicroRNA-146a targets the L1 cell adhesion molecule and suppresses the metastatic potential of gastric cancer, Mol Med Report, 2012, 6(3): 501-506.
Han X, Fang X, Lou X, Hua D, Ding W, Foltz G, Hood L, Yuan Y, Lin B. Silencing SOX2 induced mesenchymal-epithelial transition and its expression predicts liver and lymph node metastasis of CRC patients, PLoS One, 2012, 7(8): e41335.
Fang XF, Zhang WY, Zhao N, Yu W, Ding D, Hong X, Li LS, Zhang HR, Zheng S*, Lin BY*. Genome-wide analysis of OCT4 binding sites in glioblastoma cancer cells, J Zhejiang Univ Sci B, 2011, 12(10): 812-819.
Fang X, Yoon JG, Li L, Tsai YS, Zheng S, Hood L, Goodlett DR, Foltz G, Lin B*. Landscape of the SOX2 protein-protein interactome, Proteomics, 2011, 11(5): 921-934.
Fang X, Yoon JG, Li L, Yu W, Shao J, Hua D, Zheng S, Hood L, Goodlett DR, Foltz G*, Lin B*. The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis, BMC Genomics. 2011, 12(11).
Fang X#, Yu W, Li L, Shao J, Zhao N, Chen Q, Ye Z, Lin SC, Zheng S, Lin B. ChIP-seq and Functional Analysis of the SOX2 Gene in Colorectal Cancers, OMICS, 2010, 14(4): 369-384.
Long-chain non-coding RNA AC006050.3-003 regulates cisplatin resistance in lung squamous cell carcinoma and its molecular mechanism. Funding Source: Natural Science Foundation of Zhejiang.