Fang Xuefeng, M.D., Ph.D.

Department:Medical Oncology

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Associate Chief Physician


Appointment

Clinical / Research Interests

Personalized and comprehensive therapy of gastrointestinal cancer and lung cancer with chemotherapy, targeted therapy and immunotherapy.

Professional Highlights

Zhejiang Medicine and Health Innovation Award, Third Prize, 2015

Professional Appointments

Member, Chemotherapy Committee, Zhejiang Anti-Cancer Association, 2015-present

Member, Anti-Cancer Drug Committee, Zhejiang Anti-Cancer Association, 2015-present


Education Experience

Research Summary

Molecular mechanisms of cancer metastasis.

Publications

Chen C, Ge J, Lu Q, Ping G, Yang C, Fang X. Expression of Lysine-specific demethylase 1 in human epithelial ovarian cancer, J Ovarian Res, 2015, 8(28).

Hou Z, Xu C, Xie H, Xu H, Zhan P, Yu L, Fang X. Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients, PLoS One, 2014, 9(9): e108133.

Xuefeng Fang, Zhibo Hou, Xinzheng Dai, Cong Chen, Jing Ge, Hong Shen, Xiaofeng Li, Like Yu, Ying Yuan. SATB1 is overexpressed in colorectal cancer and promotes colorectal cancer cell growth and metastasis. World J Gastroenterol. 2013 Apr 21;19(15):2331-9. 

Hou Z, Yin H, Chen C, Dai X, Li X, Liu B, Fang X. MicroRNA-146a targets the L1 cell adhesion molecule and suppresses the metastatic potential of gastric cancer, Mol Med Report, 2012, 6(3): 501-506.

Han X, Fang X, Lou X, Hua D, Ding W, Foltz G, Hood L, Yuan Y, Lin B. Silencing SOX2 induced mesenchymal-epithelial transition and its expression predicts liver and lymph node metastasis of CRC patients, PLoS One, 2012, 7(8): e41335.

Fang XF, Zhang WY, Zhao N, Yu W, Ding D, Hong X, Li LS, Zhang HR, Zheng S*, Lin BY*. Genome-wide analysis of OCT4 binding sites in glioblastoma cancer cells, J Zhejiang Univ Sci B, 2011, 12(10): 812-819.

Fang X, Yoon JG, Li L, Tsai YS, Zheng S, Hood L, Goodlett DR, Foltz G, Lin B*. Landscape of the SOX2 protein-protein interactome, Proteomics, 2011, 11(5): 921-934.

Fang X, Yoon JG, Li L, Yu W, Shao J, Hua D, Zheng S, Hood L, Goodlett DR, Foltz G*, Lin B*. The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis, BMC Genomics. 2011, 12(11).

Fang X#, Yu W, Li L, Shao J, Zhao N, Chen Q, Ye Z, Lin SC, Zheng S, Lin B. ChIP-seq and Functional Analysis of the SOX2 Gene in Colorectal Cancers, OMICS, 2010, 14(4): 369-384.


Current Program

Long-chain non-coding RNA AC006050.3-003 regulates cisplatin resistance in lung squamous cell carcinoma and its molecular mechanism. Funding Source: Natural Science Foundation of Zhejiang.

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