Wu Xifeng, M.D., Ph.D.

Position:Vice Hospital President

Medical School:Fudan University, China

Academic Rank:Professor


Clinical / Research Interests

Professional Highlights

Zhejiang Scientific and Technologic Award, 1989 

D. Jack Kilian Scholarship, 1993

Richard C. Devereaux Award for Outstanding Young Investigators in Lung Cancer Prevention, Research Foundation of America, 1995 

Faculty Scholar Award, The University of Texas MD Anderson Cancer Center, 2002 

Ashbel Smith Professorship, The University of Texas, 2006-2008 

Best Boss Award Finalists, The University of Texas MD Anderson Cancer Center, 2007 

Certificate for Exceptional Leadership and Support as a Mentor at The University of Texas MD Anderson Cancer Center, 2007 

Betty B. Marcus Chair in Cancer Prevention, MD Anderson Cancer Center, 2008-2019 

Julie and Ben Rogers Award for Research Excellence, The University of Texas MD Anderson Cancer Center, 2008 

Senior Fellow of the MD Anderson Research Trust, The University of Texas MD Anderson Cancer Center, 2008-2013 

The Margaret and James A. Elkins, Jr. Faculty Achievement Award in Cancer Prevention, The University of Texas MD Anderson Cancer Center, 2008 

Certificate for Exceptional Leadership and Support as a Mentor at The University of Texas MD Anderson Cancer Center, 2008 

Certificate for Exceptional Leadership and Support as a Mentor at The University of Texas MD Anderson Cancer Center, 2009 

Leading Mentor in Cancer Prevention of 2016, Division of Cancer Prevention and Population Services, 2010 

Certificate for Exceptional Leadership and Support as a Mentor at The University of Texas MD Anderson Cancer Center, 2011 

Robert M. Chamberlain Distinguished Mentor Award, The University of Texas MD Anderson Cancer Center, 2011 

Wall of Science Publication Gallery Inclusion, The University of Texas MD Anderson Cancer Center, 2012 

Certificate for Exceptional Leadership and Support as a Mentor at The University of Texas MD Anderson Cancer Center, 2012 

Certificate for Exceptional Leadership and Support as a Mentor at The University of Texas MD Anderson Cancer Center, 2013 

Houston's 50 Most Influential Women, 2014 

Outstanding Contribution Award, International Interdisciplinary Colon and Rectal Cancer Conference, Shanghai, China, 2015 

Leading Mentor in Cancer Prevention of 2016, Division of Cancer Prevention and Population Services, 2016


Professional Appointments

Dean and Profesor, School of Public Health, Zhejiang University School of Medicine 

Director, National Institute for Data Science in Health and Medicine, Zhejiang University


Education Experience

M.S. Med, Occupational Health, Zhejiang University, China, 1987 

Postdoctoral Fellow, Cell Biology, National Laboratory of Industrial Environment and Risk Analysis, Verneuil-en-Halatte, France, 1990-1991

Ph.D., Epidemiology, The University of Texas Health Science Center at Houston School of Public Health, US, 1994, 



Research Summary

Publications

Wu X, Li W, Tu H. Big data and artificial intelligence in cancer research. Trends in Cancer. 2023 Nov 15.

Pan J, Hu K, Yu X, Li W, Shen Y, Song Z, Guo Y, Yang M, Hu F, Xia Q, Du Z, Wu XF. Beneficial associations between outdoor visible greenness at the workplace and metabolic syndrome in Chinese adults. Environment International. 2023 Nov 21:108327.

Li W, Wen CP, Li W, Ying Z, Pan S, Li Y, Zhu Z, Yang M, Tu H, Guo Y, Song Z, Chu DT, Wu XF. 6-Year trajectory of fasting plasma glucose (FPG) and mortality risk among individuals with normal FPG at baseline: a prospective cohort study. Diabetology & Metabolic Syndrome. 2023 Aug 13;15(1):169.

Ying Z, Wen CP, Tu H, Li W, Pan S, Li Y, Luo Y, Zhu Z, Yang M, Song Z, Chu DT, Wu XF. Association of fat mass and fat‐free mass with all‐cause and cause‐specific mortality in Asian individuals: A prospective cohort study. Obesity. 2023 Dec;31(12):3043-55.

Wang S, Li W, Li S, Tu H, Jia J, Zhao W, Xu A, Xu W, Tsai MK, Chu DT, Wen CP, Wu XF. Association between plant-based dietary pattern and biological aging trajectory in a large prospective cohort. BMC medicine. 2023 Aug 17;21(1):310.

Pan S, Zhao W, Li Y, Ying Z, Luo Y, Wang Q, Li X, Lu W, Dong X, Wu Y, Wu X. Prediction of risk and overall survival of pancreatic cancer from blood soluble immune checkpoint-related proteins. Frontiers in Immunology. 2023 May 15;14:1189161.

Wang S, Wen CP, Li W, Li S, Sun M, Xu A, Tsai MK, Chu DT, Tsai SP, Tu H, Wu X. Development of a Novel Multidimensional Measure of Aging to Predict Mortality and Morbidity in the Prospective MJ Cohort. The Journals of Gerontology: Series A. 2023 Apr 1;78(4):690-7.

Cao Z, Li W, Wen CP, Li S, Chen C, Jia Q, Li W, Zhang W, Tu H, Wu X. Risk of Death Associated With Reversion From Prediabetes to Normoglycemia and the Role of Modifiable Risk Factors. JAMA Network Open. 2023 Mar 1;6(3):e234989-.

Zhang J, Cao X, Chen C, He L, Ren Z, Xiao J, Han L, Wu X, Liu Z. Predictive utility of mortality by aging measures at different hierarchical levels and the response to modifiable life style factors: implications for geroprotective programs. Frontiers in Medicine. 2022 Apr 22;9:831260.

Tu H, Ye Y, Huang M, Xie K, Chow WH, Zhao H, Wu X. Smoking, smoking cessation, and survival after cancer diagnosis in 128,423 patients across cancer types. Cancer Communications. 2022 Dec;42(12):1421.

Tu H, McQuade JL, Davies MA, Huang M, Xie K, Ye Y, Chow WH, Rodriguez A, Wu X. Body mass index and survival after cancer diagnosis: A pan-cancer cohort study of 114 430 patients with cancer. The Innovation. 2022 Nov 8;3(6).

Wang Q, He Y, Li W, Xu X, Hu Q, Bian Z, Xu A, Tu H, Wu M, Wu X. Soluble immune checkpoint-related proteins in blood are associated with invasion and progression in non-small cell lung cancer. Frontiers in Immunology. 2022 Jul 6;13:887916.

Feng X, Guo Y, Tu H, Li S, Chen C, Sun M, Wang S, Li B, Wu X, Song Z. Temporal changes in serum uric acid and risk for metabolic syndrome: a longitudinal cohort study. Diabetology & Metabolic Syndrome. 2022 Dec;14(1):1-0.

Sun MX, Wen QB, Tu HK, Li S, Feng X, Wang SC, Wu XF. Associations between multimorbidity patterns of 4 chronic diseases and physical activity with all-cause mortality. Chinese Journal of Epidemiology. 2022 Dec 1;43(12):1952-8.

Yu X, Chen C, Guo Y, Tong Y, Zhao Y, Wu L, Sun X, Wu X, Song Z. High NAFLD fibrosis score in non-alcoholic fatty liver disease as a predictor of carotid plaque development: a retrospective cohort study based on regular health check-up data in China. Annals of Medicine. 2021 Jan 1;53(1):1621-31.

Li S, Chen C, Cao S, Hu K, Lei H, Xu X, Wang Q, Yuan C, Wang S, Wang S, Jia J, Ye Y, Wu X. Trend analysis and intervention effect starting point detection of COVID-19 epidemics using recalibrated time series models—worldwide, 2020. China CDC Weekly. 2021 May 5;3(20):417.

Wang Q, Ye Y, Yu H, Lin SH, Tu H, Liang D, Chang DW, Huang M, Wu X. Immune checkpoint-related serum proteins and genetic variants predict outcomes of localized prostate cancer, a cohort study. Cancer Immunology, Immunotherapy. 2021 Mar;70:701-12.

Ye Y, Lei H, Chen C, Hu K, Xu X, Yuan C, Cao S, Wang S, Li S, Ying Z, Jia J, Wang Q, Sten H V, Xu Z, Wu X. Predicting COVID-19 epidemiological trend by applying population mobility data in two-stage modeling. Journal of Zhejiang University. Medical Sciences. 2021 Feb 1;50(1):68-73.

Wang S, Ye Y, Xu X, Yuan C, Li S, Cao S, Li W, Chen C, Hu K, Lei H, Zhu H, Zhu Y, Wu X. Impact of socioeconomic status, population mobility and control measures on COVID-10 development in major cities of China. Zhejiang da xue xue bao. Yi xue ban= Journal of Zhejiang University. Medical Sciences. 2021 Feb 1;50(1):52-60.

Wang S, Ye Y, Hu K, Lei H, Chen C, Xu X, Li W, Yuan C, Cao S, Li S, Jia J, Wang Q, Bian Z, Wu X. Impact of Wuhan lockdown on the spread of COVID-19 in China: a study based on the data of population mobility. Zhejiang da xue xue bao. Yi xue ban= Journal of Zhejiang University. Medical Sciences. 2021 Feb 1;50(1):61-7.

Wu X, Ye Y. A public health perspective on preventing and controlling the spread of coronavirus disease 2019. China CDC Weekly. 2020 Apr 4;2(14):237.

Wang Q, Gu J, Wang L, Chang DW, Ye Y, Huang M, Roth JA, Wu X. Genetic associations of T cell cancer immune response-related genes with T cell phenotypes and clinical outcomes of early-stage lung cancer. Journal for immunotherapy of cancer. 2020;8(2).

Wu X, Xu X, Wang X. lessons from China's Zhejiang Province and Hangzhou on how countries can prevent and rebound from an epidemic like COVID-19. InThe World Economic Forum COVID Action Platform [Online] 2020 Mar 12.

Wang Q, Zhang J, Tu H, Liang D, Chang DW, Ye Y, Wu X. Soluble immune checkpoint-related proteins as predictors of tumor recurrence, survival, and T cell phenotypes in clear cell renal cell carcinoma patients. Journal for immunotherapy of cancer. 2019 Dec;7:1-9.

Wang Q, Tu H, Zhu M, Liang D, Ye Y, Chang DW, Long Y, Wu X. Circulating obesity-driven biomarkers are associated with risk of clear cell renal cell carcinoma: a two-stage, case-control study. Carcinogenesis. 2019 Oct 16;40(10):1191-7.

Xie K, Chen CH, Tsai SP, Lu PJ, Wu H, Zeng Y, Ye Y, Tu H, Wen C, Huang M, Zhang Y, Lee, J, Tsai, M, Wen, C, Wu, X. Loss of life expectancy by 10 years or more from elevated aspartate aminotransferase: finding aspartate aminotransferase a better mortality predictor for all-cause and liver-related than alanine aminotransferase. Official journal of the American College of Gastroenterology| ACG. 2019 Sep 1;114(9):1478-87.

Zhao H, Shen J, Moore SC, Ye Y, Wu X, Zanetti KA, Esteva FJ, Tripathy D, Chow WH. Breast cancer risk in relation to plasma metabolites among Hispanic and African American women. Breast Cancer Res Treat. 2019 Feb 15. doi: 10.1007/s10549-019-05165-4.  

Zhu Y, Wei Y, Zhang R, Dong X, Shen S, Zhao Y, Bai J, Albanes D, Caporaso NE, Landi MT, Zhu B, Chanock SJ, Gu F, Lam S, Tsao MS, Shepherd FA, Tardon A, Fernández-Somoano A, Fernandez-Tardon G, Chen C, Barnett MJ, Doherty J, Bojesen SE, Johansson M, Brennan P, McKay JD, Carreras-Torres R, Muley T, Risch A, Wichmann HE, Bickeboeller H, Rosenberger A, Rennert G, Saliba W, Arnold SM, Field JK, Davies MPA, Marcus MW, Wu X, Ye Y, Le Marchand L, Wilkens LR, Melander O, Manjer J, Brunnstr?m H, Hung RJ, Liu G, Brhane Y, Kachuri L, Andrew AS, Duell EJ, Kiemeney LA, van der Heijden EHFM, Haugen A, Zienolddiny S, Skaug V, Grankvist K, Johansson M, Woll PJ, Cox A, Taylor F, Teare DM, Lazarus P, Schabath MB, Aldrich MC, Houlston RS, McLaughlin J, Stevens VL, Shen H, Hu Z, Dai J, Amos CI, Han Y, Zhu D, Goodman GE, Chen F, Christiani DC. Elevated platelet count appears to be causally associated with increased risk of lung cancer: A Mendelian randomization analysis. Cancer Epidemiol Biomarkers Prev. 2019 3, Jan 30. pii:cebp.0356.2018.  

Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP, Han Y, Michailidou K, Lesseur C, Kuchenbaecker KB, Dennis J, Conti DV, Casey G, Gaudet MM, Huyghe JR, Albanes D, Aldrich MC, Andrew AS, Andrulis IL, Anton-Culver H, Antoniou AC, Antonenkova NN, Arnold SM, Aronson KJ, Arun BK, Bandera EV, Barkardottir RB, Barnes DR, Batra J, Beckmann MW, Benitez J, Benlloch S, Berchuck A, Berndt SI, Bickeb?ller H, Bien SA, Blomqvist C, Boccia S, Bogdanova NV, Bojesen SE, Bolla MK, Brauch H, Brenner H, Brenton JD, Brook MN, Brunet J, Brunnstr?m H, Buchanan DD, Burwinkel B, Butzow R, Cadoni G, Caldés T, Caligo MA, Campbell I, Campbell PT, Cancel-Tassin G, Cannon-Albright L, Campa D, Caporaso N, Carvalho AL, Chan AT, Chang-Claude J, Chanock SJ, Chen C, Christiani DC, Claes KBM, Claessens F, Clements J, Collée JM, Correa MC, Couch FJ, Cox A, Cunningham JM, Cybulski C, Czene K, Daly MB, deFazio A, Devilee P, Diez O, Gago-Dominguez M, Donovan JL, D?rk T, Duell EJ, Dunning AM, Dwek M, Eccles DM, Edlund CK, Edwards DRV, Ellberg C, Evans DG, Fasching PA, Ferris RL, Liloglou T, Figueiredo JC, Fletcher O, Fortner RT, Fostira F, Franceschi S, Friedman E, Gallinger SJ, Ganz PA, Garber J, García-Sáenz JA, Gayther SA, Giles GG, Godwin AK, Goldberg MS, Goldgar DE, Goode EL, Goodman MT, Goodman G, Grankvist K, Greene MH, Gronberg H, Gronwald J, Guénel P, H?kansson N, Hall P, Hamann U, Hamdy FC, Hamilton RJ, Hampe J, Haugen A, Heitz F, Herrero R, Hillemanns P, Hoffmeister M, H?gdall E, Hong YC, Hopper JL, Houlston R, Hulick PJ, Hunter DJ, Huntsman DG, Idos G, Imyanitov EN, Ingles SA, Isaacs C, Jakubowska A, James P, Jenkins MA, Johansson M, Johansson M, John EM, Joshi AD, Kaneva R, Karlan BY, Kelemen LE, Kühl T, Khaw KT, Khusnutdinova E, Kibel AS, Kiemeney LA, Kim J, Kjaer SK, Knight JA, Kogevinas M, Kote-Jarai Z, Koutros S, Kristensen VN, Kupryjanczyk J, Lacko M, Lam S, Lambrechts D, Landi MT, Lazarus P, Le ND, Lee E, Lejbkowicz F, Lenz HJ, Leslie G, Lessel D, Lester J, Levine DA, Li L, Li CI, Lindblom A, Lindor NM, Liu G, Loupakis F, Lubi駍ki J, Maehle L, Maier C, Mannermaa A, Marchand LL, Margolin S, May T, McGuffog L, Meindl A, Middha P, Miller A, Milne RL, MacInnis RJ, Modugno F, Montagna M, Moreno V, Moysich KB, Mucci L, Muir K, Mulligan AM, Nathanson KL, Neal DE, Ness AR, Neuhausen SL, Nevanlinna H, Newcomb PA, Newcomb LF, Nielsen FC, Nikitina-Zake L, Nordestgaard BG, Nussbaum RL, Offit K, Olah E, Olama AAA, Olopade OI, Olshan AF, Olsson H, Osorio A, Pandha H, Park JY, Pashayan N, Parsons MT, Pejovic T, Penney KL, Peters WHM, Phelan CM, Phipps AI, Plaseska-Karanfilska D, Pring M, Prokofyeva D, Radice P, Stefansson K, Ramus SJ, Raskin L, Rennert G, Rennert HS, van Rensburg EJ, Riggan MJ, Risch HA, Risch A, Roobol MJ, Rosenstein BS, Rossing MA, De Ruyck K, Saloustros E, Sandler DP, Sawyer EJ, Schabath MB, Schleutker J, Schmidt MK, Setiawan VW, Shen H, Siegel EM, Sieh W, Singer CF, Slattery ML, Sorensen KD, Southey MC, Spurdle AB, Stanford JL,Stevens VL, Stintzing S, Stone J, Sundfeldt K, Sutphen R, Swerdlow AJ, Tajara EH, Tangen CM, Tardon A, Taylor JA, Teare MD, Teixeira MR, Terry MB, Terry KL, Thibodeau SN, Thomassen M, Bj?rge L, Tischkowitz M, Toland AE, Torres D, Townsend PA, Travis RC, Tung N, Tworoger SS, Ulrich CM, Usmani N, Vachon CM, Van Nieuwenhuysen E, Vega A, Aguado-Barrera ME, Wang Q, Webb PM, Weinberg CR, Weinstein S, Weissler MC, Weitzel JN, West CML, White E, Whittemore AS, Wichmann HE, Wiklund F, Winqvist R, Wolk A, Woll P, Woods M, Wu AH, Wu X, Yannoukakos D, Zheng W, Zienolddiny S, Ziogas A, Zorn KK, Lane JM, Saxena R, Thomas D, Hung RJ, Diergaarde B, McKay J, Peters U, Hsu L, García-Closas M, Eeles RA, Chenevix-Trench G, Brennan PJ, Haiman CA, Simard J, Easton DF, Gruber SB, Pharoah PDP, Price AL, Pasaniuc B, Amos CI, Kraft P, Lindstr?m S. Shared heritability and functional enrichment across six solid cancers. Nat Commun. 2019 Jan 25;10(1):431. doi: 10.1038/s41467-018-08054-4. PMID: 30683880

Johansson M, Carreras-Torres R, Scelo G, Purdue MP, Mariosa D, Muller DC, Timpson NJ, Haycock PC, Brown KM, Wang Z, Ye Y, Hofmann JN, Foll M, Gaborieau V, Machiela MJ, Colli LM, Li P, Garnier JG, Blanche H, Boland A, Burdette L, Prokhortchouk E, Skryabin KG, Yeager M, Radojevic-Skodric S, Ognjanovic S, Foretova L, Holcatova I, Janout V, Mates D, Mukeriya A, Rascu S, Zaridze D, Bencko V, Cybulski C, Fabianova E, Jinga V, Lissowska J, Lubinski J, Navratilova M, Rudnai P, Benhamou S, Cancel-Tassin G, Cussenot O, Weiderpass E, Ljungberg B, Tumkur Sitaram R, H?ggstr?m C, Bruinsma F, Jordan SJ, Severi G, Winship I, Hveem K, Vatten LJ, Fletcher T, Larsson SC, Wolk A, Banks RE, Selby PJ, Easton DF, Andreotti G, Beane Freeman LE, Koutros S, M?nnist? S, Weinstein S, Clark PE, Edwards TL, Lipworth L, Gapstur SM, Stevens VL, Carol H, Freedman ML, Pomerantz MM, Cho E, Wilson KM, Gaziano JM, Sesso HD, Freedman ND, Parker AS, Eckel-Passow JE, Huang WY, Kahnoski RJ, Lane BR, Noyes SL, Petillo D, Teh BT, Peters U, White E, Anderson GL, Johnson L, Luo J, Buring J, Lee IM, Chow WH, Moore LE, Eisen T, Henrion M, Larkin J, Barman P, Leibovich BC, Choueiri TK, Lathrop GM, Deleuze JF, Gunter M, McKay JD, Wu X, Houlston RS, Chanock SJ, Relton C, Richards JB, Martin RM, Davey Smith G, Brennan P. The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study. PLoS Med. 2019 Jan 3;16(1):e1002724. doi: 10.1371/journal.pmed.1002724. eCollection 2019 Jan. PMID: 30605491

Shen J, Chrisman M, Wu X, Chow WH, Zhao H. Sleep duration and risk of cancer in the Mexican American Mano-a-Mano Cohort. Sleep Health. 2019 Feb;5(1):78-83. doi: 10.1016/j.sleh.2018.09.004. Epub 2018 Oct 30. PMID: 30670171

Dai J, Li Z, Amos CI, Hung RJ, Tardon A, Andrew A, Chen C, Christiani DC, Albanes D, van der Heijden EHFM, Duell E, Rennert G, James MD, Yuan JM, Field JK, Jonas M, Grankvist K, Le Marchand L, Teare MD, Schabath MB, Aldrich MC, Tsao MS, Lazarus P, Stephen L, Bojesen SE, Susanne A, Wu X, Haugen A, Vladimir J, Johansson M, Yonathan B, Fernandez-Somoano A, Kiemeney LA, Davies M, Zienolddiny S, Hu Z, Shen H. Systematic analyses of regulatory variants in DNase I hypersensitive sites identified two novel lung cancer susceptibility loci. Carcinogenesis. 2018 Dec 24. doi: 10.1093/carcin/bgy187. [Epub ahead of print] PMID: 30590402

Wang Q, Gregg JR, Gu J, Ye Y, Chang DW, Davis JW, Thompson TC, Kim J, Logothetis CJ, Wu X. Genetic associations of T cell cancer immune response with tumor aggressiveness in localized prostate cancer patients and disease reclassification in an active surveillance cohort. Oncoimmunology. 2018 Oct 29;8(1):e1483303. doi: 10.1080/2162402X.2018.1483303. eCollection 2019. PMID: 30546938

Zhou W, Machiela MJ, Freedman ND, Rothman N, Malats N, Dagnall C, Caporaso N, Teras LT, Gaudet MM, Gapstur SM, Stevens VL, Jacobs KB, Sampson J, Albanes D, Weinstein S, Virtamo J, Berndt S, Hoover RN, Black A, Silverman D, Figueroa J, Garcia-Closas M, Real FX, Earl J, Marenne G, Rodriguez-Santiago B, Karagas M, Johnson A, Schwenn M, Wu X, Gu J, Ye Y, Hutchinson A, Tucker M, Perez-Jurado LA, Dean M, Yeager M, Chanock SJ. Reply to 'Mosaic loss of chromosome Y in leukocytes matters'. Nat Genet. 2019 Jan;51(1):7- PMID: 30514911

Wu X, Ye Y. Response. J Natl Cancer Inst. 2017 Jul 1;109(7). PMID: 29982756 

Carbone M, Amelio I, Affar EB, Brugarolas J, Cannon-Albright LA, Cantley LC, Cavenee WK, Chen Z, Croce CM, Andrea A, Gandara D, Giorgi C, Jia W, Lan Q, Mak TW, Manley JL, Mikoshiba K, Onuchic JN, Pass HI, Pinton P, Prives C, Rothman N, Sebti SM, Turkson J, Wu X, Yang H, Yu H, Melino G. Consensus report of the 8 and 9th Weinman Symposia on Genex Environment Interaction in carcinogenesis: novel opportunities for precision medicine. Cell Death Differ. 2018 Nov;25(11):1885-1904. doi: 10.1038/s41418-018-0213-5. Epub 2018 Oct 15. PMID: 30323273

Zhang Y, Roth JA, Yu H, Ye Y, Xie K, Zhao H, Chang DW, Huang M, Li H, Qu J, Wu X. A 5-MicroRNA Signature Identified from Serum MicroRNA Profiling Predicts Survival in Patients with Advanced Stage Non-Small Cell Lung Cancer. Carcinogenesis. 2018 Nov 14. doi: 10.1093/carcin/bgy132. [Epub ahead of print] PMID: 30428030

Ferreiro-Iglesias A, Lesseur C, McKay J, Hung RJ, Han Y, Zong X, Christiani D, Johansson M, Xiao X, Li Y, Qian DC, Ji X, Liu G, Caporaso N, Scelo G, Zaridze D, Mukeriya A, Kontic M, Ognjanovic S, Lissowska J, Szo砶owska M, Swiatkowska B, Janout V, Holcatova I, Bolca C, Savic M, Ognjanovic M, Bojesen SE, Wu X, Albanes D, Aldrich MC, Tardon A, Fernandez-Somoano A, Fernandez-Tardon G, Le Marchand L, Rennert G, Chen C, Doherty J, Goodman G, Bickeb?ller H, Wichmann HE, Risch A, Rosenberger A, Shen H, Dai J, Field JK, Davies M, Woll P, Teare MD, Kiemeney LA, van der Heijden EHFM, Yuan JM, Hong YC, Haugen A, Zienolddiny S, Lam S, Tsao MS, Johansson M, Grankvist K, Schabath MB, Andrew A, Duell E, Melander O, Brunnstr?m H, Lazarus P, Arnold S, Slone S, Byun J, Kamal A, Zhu D, Landi MT, Amos CI, Brennan P. Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity. Nat Commun. 2018 Sep 25;9(1):3927. doi: 10.1038/s41467-018- 05890-2. PMID: 30254314 

Gu J, Zhang J, Zheng L, Ajani JA, Wu X, Ye Y. Serum miR-331-3p predicts tumor recurrence in esophageal adenocarcinoma. Sci Rep. 2018 Sep 18;8(1):14006. doi: 10.1038/s41598-018-32282-9. PMID: 30228315 

Zhang J, Ye Y, Chang DW, Lin SH, Huang M, Tannir NM, Matin S, Karam JA, Wood CG, Chen ZN, Wu X. Global and Targeted miRNA Expression Profiling in Clear Cell Renal Cell Carcinoma Tissues Potentially Links miR-155-5p and miR-210-3p to Both Tumorigenesis and Recurrence. Am J Pathol. 2018 Sep 8. pii: S0002-9440(18)30201-3. doi:10.1016/j.ajpath.2018.07.026. [Epub ahead of print] PMID: 30201497

Ji X, Bossé Y, Landi MT, Gui J, Xiao X, Qian D, Joubert P, Lamontagne M, Li Y, Gorlov I, de Biasi M, Han Y, Gorlova O, Hung RJ, Wu X, McKay J, Zong X, Carreras-Torres R, Christiani DC, Caporaso N, Johansson M, Liu G, Bojesen SE, Le Marchand L, Albanes D, Bickeb?ller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Chen C, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Shen H, Hong YC, Yuan JM, Bertazzi PA, Pesatori AC, Ye Y, Diao N, Su L, Zhang R, Brhane Y, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman C, Wilkens L, Fernandez-Somoano A, Fernandez-Tardon G, van der Heijden EHFM, Kim JH, Dai J, Hu Z, Davies MPA, Marcus MW, Brunnstr?m H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Doherty J, Goodman GE, Cox A, Taylor F, Woll P, Brüske I, Manz J, Muley T, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd F, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Koh WP, Gao YT, Houlston R, McLaughlin J, Stevens V, Nickle DC, Obeidat M, Timens W, Zhu B, Song L, Artigas MS, Tobin MD, Wain LV, Gu F, Byun J, Kamal A, Zhu D, Tyndale RF, Wei WQ, Chanock S, Brennan P, Amos CI. Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk. Nat Commun. 2018 Aug 13;9(1):3221. doi: 10.1038/s41467-018-05074-y. PMID: 30104567

Kelemen LE, Earp M, Fridley BL, Chenevix-Trench G; Australian Ovarian Cancer Study Group, Fasching PA, Beckmann MW, Ekici AB, Hein A, Lambrechts D, Lambrechts S, Van Nieuwenhuysen E, Vergote I, Rossing MA, Doherty JA, Chang-Claude J, Behrens S,Moysich KB, Cannioto R, Lele S, Odunsi K, Goodman MT, Shvetsov YB, Thompson PJ, Wilkens LR, D?rk T, Antonenkova N, Bogdanova N, Hillemanns P, Runnebaum IB, du Bois A, Harter P, Heitz F, Schwaab I, Butzow R, Pelttari LM, Nevanlinna H, Modugno F, Edwards RP, Kelley JL, Ness RB, Karlan BY, Lester J, Orsulic S, Walsh C, Kjaer SK, Jensen A, Cunningham JM, Vierkant RA, Giles GG, Bruinsma F, Southey MC, Hildebrandt MAT, Liang D, Lu K, Wu X, Sellers TA, Levine DA, Schildkraut JM, Iversen ES, Terry KL, Cramer DW, Tworoger SS, Poole EM, Bandera EV, Olson SH, Orlow I, Vestrheim Thomsen LC, Bjorge L, Krakstad C, Tangen IL, Kiemeney LA, Aben KKH, Massuger LFAG, van Altena AM, Pejovic T, Bean Y, Kellar M, Cook LS, Le ND, Brooks-Wilson A, Gronwald J, Cybulski C, Jakubowska A, Lubi駍ki J, Wentzensen N, Brinton LA, Lissowska J, Hogdall E, Engelholm SA, Hogdall C, Lundvall L, Nedergaard L, Pharoah PDP, Dicks E, Song H, Tyrer JP, McNeish I, Siddiqui N, Carty K, Glasspool R, Paul J, Campbell IG, Eccles D, Whittemore AS, McGuire V, Rothstein JH, Sieh W, Narod SA, Phelan CM, McLaughlin JR, Risch HA, Anton-Culver H, Ziogas A, Menon U, Gayther SA, Gentry-Maharaj A, Ramus SJ, Wu AH, Pearce CL, Lee AW, Pike MC, Kupryjanczyk J, Podgorska A, Plisiecka-Halasa J, Sawicki W, Goode EL, Berchuck A; Ovarian Cancer Association Consortium. rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology. Int J Mol Sci. 2018 Aug 21;19(9). pii: E2473. doi: 10.3390/ijms19092473. PMID: 30134598

Kachuri L, Saarela O, Bojesen SE, Davey Smith G, Liu G, Landi MT, Caporaso NE, Christiani DC, Johansson M, Panico S, Overvad K, Trichopoulou A, Vineis P, Scelo G, Zaridze D, Wu X, Albanes D, Diergaarde B, Lagiou P, Macfarlane GJ, Aldrich MC, Tardón A, Rennert G, Olshan AF, Weissler MC, Chen C, Goodman GE, Doherty JA, Ness AR, Bickeb?ller H, Wichmann HE, Risch A, Field JK, Teare MD, Kiemeney LA, van der Heijden EHFM, Carroll JC, Haugen A, Zienolddiny S, Skaug V, Wünsch-Filho V, Tajara EH, Ayoub Moysés R, Daumas Nunes F, Lam S, Eluf-Neto J, Lacko M, Peters WHM, Le Marchand L, Duell EJ, Andrew AS, Franceschi S, Schabath MB, Manjer J, Arnold S, Lazarus P, Mukeriya A, Swiatkowska B, Janout V, Holcatova I, Stojsic J, Mates D, Lissowska J, Boccia S, Lesseur C, Zong X, McKay JD, Brennan P, Amos CI, Hung RJ. Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers. Int J Epidemiol. 2018 Jul 28. doi: 10.1093/ije/dyy140. [Epub ahead of print] PMID: 30059977 

Pierzynski JA, Ye Y, Lippman SM, Rodriguez MA, Wu X, Hildebrandt MAT.Socio-demographic, Clinical, and Genetic Determinants of Quality of Life in Lung Cancer Patients. Sci Rep. 2018 Jul 13;8(1):10640. doi: 10.1038/s41598-018-25712-1. PMID: 30006595

Earp M, Tyrer JP, Winham SJ, Lin HY, Chornokur G, Dennis J, Aben KKH, Anton-Culver H, Antonenkova N, Bandera EV, Bean YT, Beckmann MW, Bjorge L, Bogdanova N, Brinton LA, Brooks-Wilson A, Bruinsma F, Bunker CH, Butzow R, Campbell IG, Carty K, Chang-Claude J, Cook LS, Cramer DW, Cunningham JM, Cybulski C, Dansonka-Mieszkowska A, Despierre E, Doherty JA, D?rk T, du Bois A, Dürst M, Easton DF, Eccles DM, Edwards RP, Ekici AB, Fasching PA, Fridley BL, Gentry-Maharaj A, Giles GG, Glasspool R, Goodman MT, Gronwald J, Harter P, Hein A, Heitz F, Hildebrandt MAT, Hillemanns P, Hogdall CK, H?gdall E, Hosono S, Iversen ES, Jakubowska A, Jensen A, Ji BT, Jung AY, Karlan BY, Kellar M, Kiemeney LA, Kiong Lim B, Kjaer SK, Krakstad C, Kupryjanczyk J, Lambrechts D, Lambrechts S, Le ND, Lele S, Lester J, Levine DA, Li Z, Liang D, Lissowska J, Lu K, Lubinski J, Lundvall L, Massuger LFAG, Matsuo K, McGuire V, McLaughlin JR, McNeish I, Menon U, Milne RL, Modugno F, Moysich KB, Ness RB, Nevanlinna H, Odunsi K, Olson SH, Orlow I, Orsulic S, Paul J, Pejovic T, Pelttari LM, Permuth JB, Pike MC, Poole EM, Rosen B, Rossing MA, Rothstein JH, Runnebaum IB, Rzepecka IK, Schernhammer E, Schwaab I, Shu XO, Shvetsov YB, Siddiqui N, Sieh W, Song H, Southey MC, Spiewankiewicz B, Sucheston-Campbell L, Tangen IL, Teo SH, Terry KL, Thompson PJ, Thomsen L, Tworoger SS, van Altena AM, Vergote I, Vestrheim Thomsen LC, Vierkant RA, Walsh CS, Wang-Gohrke S, Wentzensen N, Whittemore AS, Wicklund KG, Wilkens LR, Woo YL, Wu AH, Wu X, Xiang YB, Yang H, Zheng W, Ziogas A, Lee AW, Pearce CL, Berchuck A, Schildkraut JM, Ramus SJ, Monteiro ANA, Narod SA, Sellers TA, Gayther SA, Kelemen LE, Chenevix-Trench G, Risch HA, Pharoah PDP, Goode EL, Phelan CM. Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. PLoS One. 2018 Jul 6;13(7):e0197561. doi: 10.1371/journal.pone.0197561. eCollection 2018. PMID: 29979793

Byun J, Schwartz AG, Lusk C, Wenzlaff AS, de Andrade M, Mandal D, Gaba C, Yang P, You M, Kupert EY, Anderson MW, Han Y, Li Y, Qian D, Stilp A, Laurie C, Nelson S, Zheng W, Hung RJ, Gaborieau V, Mckay J, Brennan P, Caporaso NE, Landi MT, Wu X, McLaughlin JR, Brhane Y, Bossé Y, Pinney SM, Bailey-Wilson JE, Amos CI. Genome-Wide Association Study of Familial Lung Cancer. Carcinogenesis. 2018 Jun 19. doi: 10.1093/carcin/bgy080.[Epub ahead of print] PMID: 29924316

Jiao J, Watt GP, Stevenson HL, Calderone TL, Fisher-Hoch SP, Ye Y, Wu X, Vierling JM, Beretta L. Telomerase reverse transcriptase mutations in plasma DNA in patients with hepatocellular carcinoma or cirrhosis: Prevalence and risk factors. Hepatol Commun. 2018 Apr 27;2(6):718-731. doi: 10.1002/hep4.1187. eCollection 2018 Jun. PMID: 29881823

Jiao J, Watt GP, Stevenson HL, Calderone TL, Fisher-Hoch SP, Ye Y, Wu X, Vierling JM, Beretta L. Telomerase reverse transcriptase mutations in plasma DNA in patients with hepatocellular carcinoma or cirrhosis: Prevalence and risk factors. Hepatol Commun. 2018 Apr 27;2(6):718-731. doi: 10.1002/hep4.1187. eCollection 2018 Jun. PMID: 29881823

Zhao H, Chang D, Ye Y, Shen J, Chow WH, Wu X. Associations of blood mitochondrial DNA copy number with social-demographics and cancer risk: results from the Mano-A-Mano Mexican American Cohort. Oncotarget. 2018 May 22;9(39):25491-25502. doi:10.18632/oncotarget.25321. eCollection 2018 May 22. PMID: 29876003

Tu H, Dinney CP, Ye Y, Grossman HB, Lerner S, Wu X. Is folic acid safe? An evidence-based study in non-muscle-invasive bladder cancer patients. Am J of Clin Nutr. 2018 Feb 1;107(2):208-216. PMID: 29529165

Tu H, Wen CP, Tsai SP, Chow WH, Wen C, Ye Y, Zhao H, Tsai MK, Huang M, Dinney CP, Tsao CK, Wu X. Cancer risk of chronic diseases and disease markers: a prospective cohort study of 405,878 individuals. BMJ. 2018 Jan 31; 360:k134. doi: 10.1136/bmj.k134. PMID: 29386192

Tu H, Wen CP, Tsai SP, Chow WH, Wen C, Ye Y, Zhao H, Tsai MK, Huang M, Dinney CP, Tsao CK, Wu X. Cancer risk of chronic diseases and disease markers: a prospective cohort study of 405,878 individuals. BMJ. 2018 Jan 31; 360:k134. doi: 10.1136/bmj.k134. PMID: 29386192


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