Wu Lei, M.D.


Medical School:Medical School of Chinese PLA, China

Academic Rank:Associate Chief Physician


Clinical / Research Interests

Neuroimmune diseases, such as neuromyelitis Optica, multiple Sclerosis, myasthenia gravis, et al. 

Neurodegenerative disease, such as Pakinson disease, multiple system atrophy, et al.

Professional Highlights

Professional Appointments

Committee Member,  Immunology Branch, Chinese Stroke Society, 2016-present

Education Experience

Research Summary


Wu L, Jiang C, Kang Y, Dai Y, Fang W, Huang P: Curcumin exerts protective effects against hypoxiareoxygenation injury via the enhancement of apurinicapyrimidinic endonuclease 1 in SHSY5Y cells: Involvement of the PI3KAKT pathway. Int J Mol Med 2020, 45(4):993-1004. 

Liu Q, Wu L, Zhao G, et al.Variants of Interferon Regulatory Factor 5 are Associated with Neither Neuromyelitis Optica Nor Multiple Sclerosis in the South eastern Han Chinese Population. Chinese Medical Journal, 2015, 128(13):1743-7.

Zhuang J, Wu L, Qian M, et al. Variants of Interleukin-7/Interleukin-7 Receptor Alpha are Associated with Both Neuromyelitis Optica and Multiple Sclerosis Among Chinese Han Population in Southeastern China. Chinese Medical Journal, 2015, 128(22):3062-8. 

Wu L, Zhang B, Kang Y, Wu W: Enhanced slow inactivation of the human skeletal muscle sodium channel causing normokalemic periodic paralysis. Cell Mol Neurobiol 2014, 34(5):707-714. 

Wu L, Wu L, Chen Y, Zhou J: A Promising Method to Distinguish Vascular Dementia From Alzheimer's Disease With Standardized Low-Resolution Brain Electromagnetic Tomography and Quantitative EEG. Clin EEG Neurosci 2014 Jul;45(3):152-7.

Current Program

The effect and mechanism of Kir4.1 channel of astrocytes on the pathogenesis of optic neuromyelitis. Funding Source: Natural Science Foundation of Zhejiang.

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