Huang Peiyu, Ph.D.

Department:Radiology

Medical School:Chongqing Medical University, China

Academic Rank:Senior Engineer


Appointment

Clinical / Research Interests

Clinical neuroimaging research.

Professional Highlights

Zhejiang Scientific and Technological Progress Award, Second Prize

Professional Appointments

Vice Chairman, Youth Committee of Radiology Section, Zhejiang Society of Radiology

Vice Chairman, Youth Committee of Radiology Section, Zhejiang Society of Biomedical Engineering

Board Member, Psychiatric Medicine Committee, Zhejiang Society for Mathematical Medicine

Member, International Society for Magnetic Resonance in Medicine

Member, Organization for Human Brain Mapping

Education Experience

Research Summary

Dr. Huang's research interest is to use advanced magnetic resonance imaging methods to investigate the mechanism of neuropsychiatric diseases, and to discover potential imaging biomarkers to help clinical diagnosis.

Publications

Li Y, Zhu Z, Chen J, Zhang M, Yang Y, Huang P (corresponding author). Dilated Perivascular Space in the Midbrain May Reflect Dopamine Neuronal Degeneration in Parkinson's Disease. Frontiers in Aging Neuroscience. 2020 Jun 5;12:161.

Huang, P., X. Guan, T. Guo, Q. Zeng, M. Xuan, Q. Gu, X. Xu, C. Zhou, J. Wu and M. Zhang, Damaged insula network contributes to depression in Parkinson's disease. Frontiers in Psychiatry, 2020. 11.

Zhang, R., P. Huang (co-first author), Y. Jiaerken, S. Wang, H. Hong, X. Luo, X. Xu, X. Yu, K. Li and Q. Zeng. Venous disruption affects white matter integrity through increased interstitial fluid in cerebral small vessel disease. Journal of Cerebral Blood Flow & Metabolism, 2020: p. 0271678X20904840.

Yu, X., Y. Jiaerken, S. Wang, H. Hong, A. Jackson, L. Yuan, M. Lou, Q. Jiang, M. Zhang and P. Huang (corresponding author). Changes in the Corticospinal Tract Beyond the Ischemic Lesion Following Acute Hemispheric Stroke: A Diffusion Kurtosis Imaging Study. Journal of Magnetic Resonance Imaging, 2020.

Wang, S., Y. Jiaerken, X. Yu, Z. Shen, X. Luo, H. Hong, J. Sun, X. Xu, R. Zhang, Y. Zhou, P. Huang (corresponding author), M. Zhang. Understanding the association between psychomotor processing speed and white matter hyperintensity: A comprehensive multi‐modality MR imaging study. Human brain mapping, 2020. 41(3): p. 605-616.

Li, Y., P. Huang (co-first author), T. Guo, X. Guan, T. Gao, W. Sheng, C. Zhou, J. Wu, Z. Song and M. Xuan. Brain structural correlates of depressive symptoms in Parkinson's disease patients at different disease stage. Psychiatry Research: Neuroimaging, 2020. 296: p. 111029.

Li, K., X. Luo, Q. Zeng, Y. Jiaerken, S. Wang, X. Xu, X. Xu, J. Xu, C. Wang, J. Zhou, P. Huang (corresponding author), M. Zhang. Interactions between sleep disturbances and Alzheimer’s disease on brain function: a preliminary study combining the static and dynamic functional MRI. Scientific Reports, 2019. 9(1): p. 1-13.

Qian, W., P. Huang (co-first author), Z. Shen, C. Wang, Y. Yang and M. Zhang, Brain gray matter volume and functional connectivity are associated with smoking cessation outcomes. Frontiers in Human Neuroscience, 2019.

Guan, X., P. Huang (co-first author), Q. Zeng, C. Liu, H. Wei, M. Xuan, Q. Gu, X. Xu, N. Wang, and X. Yu, Quantitative susceptibility mapping as a biomarker for evaluating white matter alterations in Parkinson’s disease. Brain imaging and behavior, 2018: p. 1-12.

Huang, P., Z. Shen, C. Wang, W. Qian, H. Zhang, Y. Yang, and M. Zhang, Altered White Matter Integrity in Smokers Is Associated with Smoking Cessation Outcomes. Frontiers in human neuroscience, 2017. 11: p. 438.

Li, D., P. Huang (co-first author), Y. Zang, Y. Lou, Z. Cen, Q. Gu, M. Xuan, F. Xie, Z. Ouyang, and B. Wang, Abnormal baseline brain activity in Parkinson's disease with and without REM sleep behavior disorder: A resting‐state functional MRI study. Journal of Magnetic Resonance Imaging, 2017. 46(3): p. 697-703.

Huang, P., Y. Lou, M. Xuan, Q. Gu, X. Guan, X. Xu, Z. Song, W. Luo, and M. Zhang, Cortical abnormalities in Parkinson’s disease patients and relationship to depression: A surface-based morphometry study. Psychiatry Research: Neuroimaging, 2016. 250: p. 24-28.

Song, Z., M. Zhang, and P. Huang (corresponding author), Aberrant emotion networks in early major depressive disorder patients: an eigenvector centrality mapping study. Translational psychiatry, 2016. 6(5): p. e819.

Huang, P., M. Xuan, Q. Gu, X. Yu, X. Xu, W. Luo, and M. Zhang, Abnormal amygdala function in Parkinson's disease patients and its relationship to depression. Journal of affective disorders, 2015. 183: p. 263-268.

Lou, Y., P. Huang (co-first author), D. Li, Z. Cen, B. Wang, J. Gao, M. Xuan, H. Yu, M. Zhang, and W. Luo, Altered brain network centrality in depressed Parkinson's disease patients. Movement Disorders, 2015. 30(13): p. 1777-1784.

Huang, P., X. Xu, Q. Gu, M. Xuan, X. Yu, W. Luo, and M. Zhang, Disrupted white matter integrity in depressed versus non-depressed Parkinson's disease patients: A tract-based spatial statistics study. Journal of the neurological sciences, 2014. 346(1): p. 145-148.

Huang, X., P. Huang (co-first author),  D. Li, Y. Zhang, T. Wang, J. Mu, Q. Li, and P. Xie, Early brain changes associated with psychotherapy in major depressive disorder revealed by resting-state fMRI: evidence for the top-down regulation theory. International Journal of Psychophysiology, 2014. 94(3): p. 437-444.

Huang, P., L. Qiu, L. Shen, Y. Zhang, Z. Song, Z. Qi, Q. Gong, and P. Xie, Evidence for a left‐over‐right inhibitory mechanism during figural creative thinking in healthy nonartists. Human brain mapping, 2013. 34(10): p. 2724-2732.

Wang, T., X. Huang, P. Huang (co-first author), D. Li, F. Lv, Y. Zhang, L. Zhou, D. Yang, and P. Xie, Early-stage psychotherapy produces elevated frontal white matter integrity in adult major depressive disorder. PloS one, 2013. 8(4): p. e63081.

Current Program

A multi-modal MR Radiomics study for understanding brain degeneration and constructing computer aided diagnostic system in Parkinson's disease (PI). Funding Source: National Natural Science Foundation of Zhejiang, 2019-2022.

Using MR imaging to study the emotion circuit disruption and its leading pathological mechanism of depression in different stages of PD (PI). Funding Source: National Natural Science Foundation of Zhejiang, 2018-2021.

An MRI study of abnormal emotional circuit underlying the occurrence of depression in Parkinson's Disease (PI). Funding Source: National Natural Science Foundation of Zhejiang, 2014-2016.



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