Hu Yue, M.D., Ph.D.

Department:Breast Surgery

Medical School: Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, USA

Academic Rank:Associate Chief Physician


Clinical / Research Interests

Prevention, diagnosis and treatment of breast cancer, breast conservation surgery, breast reconstruction, mastectomy, sentinel lymph node biopsy, lumpectomy, and benign breast tumors.

Professional Highlights

Zhejiang Scientific and Technological Progress Award, First Prize, 2009

Professional Appointments

Youth Committee Member, Chinese Society of Oncology, 2018-present

Vice Chair, Youth Committee, Zhejiang Society of Oncology, 2016-present

Education Experience

Research Summary

Dr. Hu's research focuses on: 1. screening, validation and function of tumor marker candidates of breast cancer; 2. metabonomics of breast cancer; 3. translational research of breast cancer; 4. innovation and creation of surgical instruments.


Hu Y*, Qiu JL, Zhou MQ, Li XZ, Huang YQ. LAP2alpha, a novel tumor marker candidate is related to metastasis of breast cancer. Cancer Res, 2019, 79(4 Suppl): P2-01-20.

Hu Y*, Feit N, Huang YQ, Xu WH, Zheng S, Li XZ*. Gastrointestinal metastasis of primary lung cancer: An analysis of 366 cases. Oncol Lett, 2018, 15(6): 9766-9776.

Thakar M, Hu Y, Morreale M, Lerner L, Ying Lin W, Sen R, Cai Y, Karunasena E, Thakar M, Saggi S, Keer H, Ahuja N*. A novel epigenetic modulating agent sensitizes pancreatic cells to a chemotherapy agent. PLoS One, 2018, 13(6): e0199130. 

De Carvalho Fischer C, Hu Y, Morreale M, Lin WY, Wali A, Thakar M, Karunasena E, Sen R, Cai Y, Murphy L, Zahnow CA, Keer H, Thakar M*, Ahuja N*. Treatment with epigenetic agents profoundly inhibits tumor growth in leiomyosarcoma. Oncotarget, 2018, 9(27): 19379-19395.
Hu Y, Thakar M, Saggi S, Ahuja N*. Guadecitabine (SGI110) Sensitizes Pancreatic Cell Lines to Irinotecan Treatment. Ann Surg Oncol, 2017, 24(Suppl 1): PF244.

Li XF, Huang YQ, Hu Y*. Inhibition of LAP2α can suppress cell aggressiveness in breast cancer. Ann Oncol, 2016, 27(suppl 9): 48P.

Hu Y*, Li XZ, Deng YC, Zhou MQ, Zhang SZ. Primary malignant fibrous histiocytoma of the breast: a case report and review of 38 Chinese cases. Clin Breast Cancer, 2012, 12(5): 382-385.

Hu Y, Zhang SZ*, Yu JK, Liu J, Zheng S. SELDI-TOF-MS: the proteomics and bioinformatics approaches in the diagnosis of breast cancer. Breast, 2005, 14(4): 250-255.

Current Program

Systemic Research on LAP2a, a Tumor Marker Candidate of Breast Cancer. Funding Source: Natural Science Foundation of Zhejiang (LY14H160030).

Metabolic Mechanism of Heterogenicity of Cancer. Funding Source: State Key Development Program of Basic Research of China (973 Program, 2014CB542003).

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