Hu Xinlei, M.D., Ph.D.

Department:Orthopedics

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Associate Chief Physician


Appointment

Clinical / Research Interests

Orthopedic trauma specialized in microsurgery, fractures, osteomyelitis, hand disorders.

Professional Highlights

Zhejiang Scientific and Technological Progress Award, Second Prize


Professional Appointments

Membership, AO Trauma Community

Education Experience

Research Summary

The bioreactor for the cell amplification and tissue engineering.

Publications

Li J, Pan Z, Zhao Y, Hu X, Zhao X. Capitate osteotomy and transposition for type III Kienbock's disease. The Journal of hand surgery, European volume 2018, 43(7): 708-711.

Sun Y, Hu X, Li W. Antioxidant, antitumor and immunostimulatory activities of the polypeptide from Pleurotus eryngii mycelium. International journal of biological macromolecules 2017, 97: 323-330.

Xu W, Hu X. Fibroblasts induced epithelial to mesenchymal transition of tumor cells and their extra circulation traveling behavior. Medical hypotheses 2016, 89: 24-27.

Zhi L, Hu X, Xu J, Yu C, Shao H, Pan X, Hu H, Han C. The characteristics and correlation between the ischemia-reperfusion and changes of redox status in the early stage of severe burns. The American journal of emergency medicine 2015, 33(3): 338-343.

Shi Y, Wang P, Hu X, Ye Z. Evaluation of the Etoricoxib-Mediated Pain-Relieving Effect in Patients Undergoing Lumbar Fusion Procedures for Degenerative Lumbar Scoliosis: A Prospective Randomized, Double-Blind Controlled Study. Cell biochemistry and biophysics 2015, 71(3): 1313-1318.

Liang J, Zhang P, Hu X, Zhi L. Elevated serum uric acid after injury correlates with the early acute kidney in severe burns. Burns: Journal of the International Society for Burn Injuries 2015, 41(8): 1724-1731.

Hu H, Jiang H, Ren H, Hu X, Wang X, Han C. AGEs and chronic subclinical inflammation in diabetes: disorders of immune system. Diabetes/metabolism research and reviews 2015, 31(2): 127-137.

Cui W, Zhang S, Cai Z, Hu X, Zhang R, Wang Y, Li N, Chen Z, Zhang G. The antidiabetic agent glibenclamide protects airway hyperresponsiveness and inflammation in mice. Inflammation 2015, 38(2): 835-845.

Zhi L, Hu X, Han C. Biphasic changes (overreduction and overoxidation) of plasma redox status and clinical implications in early stage of severe burns. Journal of critical care 2014, 29(6): 1063-1068.

Yang H, Li T, Hu X, Wang F, Zou Y. A survey of artificial immune system based intrusion detection. TheScientificWorldJournal 2014, 2014: 156790.

Xu W, Hu X, Pan W. Tissue engineering concept in the research of the tumor biology. Technology in cancer research & treatment 2014, 13(2): 149-159.

Xu W, Hu X, Chen Z, Zheng X, Zhang C, Wang G, Chen Y, Zhou X, Tang X, Luo L, Xu X, Pan W. Normal fibroblasts induce E-cadherin loss and increase lymph node metastasis in gastric cancer. PloS one 2014, 9(5): e97306.

Wang X, Hu X, You C, Han C. Delivery of epithelial autografts and cutaneous wound healing in burn patients. Burns : journal of the International Society for Burn Injuries 2014, 40(1): 166-168.

Zhi L, Liang J, Hu X, Xu J, Yu C, Shao H, Pan X, Han C. The reliability of clinical dynamic monitoring of redox status using a new redox potential (ORP) determination method. Redox report : communications in free radical research 2013, 18(2): 63-70.

Zheng Y, Feng Z, You C, Jin Y, Hu X, Wang X, Han C. In vitro evaluation of Panax notoginseng Rg1 released from collagen/chitosan-gelatin microsphere scaffolds for angiogenesis. Biomedical engineering online 2013, 12: 134.

Wang X, You C, Hu X, Zheng Y, Li Q, Feng Z, Sun H, Gao C, Han C. The roles of knitted mesh-reinforced collagen-chitosan hybrid scaffold in the one-step repair of full-thickness skin defects in rats. Acta biomaterialia 2013, 9(8): 7822-7832.

You C, Han C, Wang X, Zheng Y, Li Q, Hu X, Sun H. The progress of silver nanoparticles in the antibacterial mechanism, clinical application and cytotoxicity. Molecular biology reports 2012, 39(9): 9193-9201.

Wang X, Li Q, Hu X, Ma L, You C, Zheng Y, Sun H, Han C, Gao C. Fabrication and characterization of poly(L-lactide-co-glycolide) knitted mesh-reinforced collagen-chitosan hybrid scaffolds for dermal tissue engineering. Journal of the mechanical behavior of biomedical materials 2012, 8: 204-215.

Sun H, Wang X, Hu X, Yu W, You C, Hu H, Han C. Promotion of angiogenesis by sustained release of rhGM-CSF from heparinized collagen/chitosan scaffolds. Journal of biomedical materials research Part B, Applied biomaterials 2012, 100(3): 788-798.

Li Q, Wang X, Hu X, Han C. A survey of diabetic foot patients with hospitalized amputations performed in a medical center over 5 years in China: limitations and lessons learnt. The international journal of lower extremity wounds 2012, 11(3): 194-200.

Hu X, Yu W, Sun H, Wang X, Han C. Epidermal cells delivered for cutaneous wound healing. The Journal of dermatological treatment 2012, 23(3): 224-237.

Yu W, Wang X, Hu X, Sun H, Han C. [Preliminary evaluation of the biological properties of poly-lactide-co-glycolic acid (PLGA) knitted mesh]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 2011, 28(1): 163-169.

Wang X, Han C, Hu X, Sun H, You C, Gao C, Haiyang Y. Applications of knitted mesh fabrication techniques to scaffolds for tissue engineering and regenerative medicine. Journal of the mechanical behavior of biomedical materials 2011, 4(7): 922-932.

Hu X, Sun H, Han C, Wang X, Yu W. Topically applied rhGM-CSF for the wound healing: a systematic review. Burns : journal of the International Society for Burn Injuries 2011, 37(5): 729-741.


Current Program

Construction of tissue-engineered skin regenerative units based on the biodegradable microcarriers in the bioreactor. Funding Source: National Nature Science Foundation of China.

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