Wen Jiaming, M.D., Ph.D.

Position:Executive Vice Chair of Urology

Department:Urology

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Chief Physician


Appointment

Clinical / Research Interests

Treatments of prostate disease, urinary stone and urinary tract tumor

Professional Highlights

Professional Appointments

Youth Committee Member, Asian Association of Andrology

Committee Member, Zhejiang Society of Sexual Medicine

Education Experience

Research Summary

Publications

Chen J, Zhang N, Wen J, Zhang Z. Silencing TAK1 alters gene expression signatures in bladder cancer cells. Oncol Lett. 2017 May;13(5):2975-2981. 

Zhang S, Gao F, Xue C, Zhang N, Gao F, Li S, Wen J. The application of wrapping ureter by a pedicled gastrocolic omentum flap combined with an artificial external scaffold to prevent stoma stenosis in rabbit after ureterocutaneostomy. Int Urol Nephrol. 2017 Feb;49(2):255-261. 

Wen J, Xu G, Du C, Wang B. Minimally invasive percutaneous nephrolithotomy versus endoscopic combined intrarenal surgery with flexible ureteroscope for partial staghorn calculi: A randomised controlled trial. Int J Surg. 2016 Apr;28:22-7.

Jiang L, Wen J, Luo W. Rho?associated kinase inhibitor, Y?27632, inhibits the  invasion and proliferation of T24 and 5367 bladder cancer cells. Mol Med Rep. 2015 Nov;12(5):7526-30.

Xu G, Wen J, Wang B, Li Z, Du C. The Clinical Efficacy and Safety of Ureteroscopic Laser Papillotomy to Treat Intraductal Papillary Calculi Associated With Medullary Sponge Kidney. Urology. 2015 Sep;86(3):472-6.

Xu G, Wen J, Li Z, Zhang Z, Gong X, Chen J, Du C. A comparative study to analyze the efficacy and safety of flexible ureteroscopy combined with holmium laser lithotripsy for residual calculi after percutaneous nephrolithotripsy. Int J Clin Exp Med. 2015 Mar 15;8(3):4501-7.

Wen J, Wang B, Du C, Xu G, Zhang Z, Li Y, Zhang N. A2B Adenosine Receptor Agonist Improves Erectile Function in Diabetic Rats. Tohoku J Exp Med. 2015;237(2):141-8.

Ning C, Wen J, Zhang Y, Dai Y, Wang W, Zhang W, Qi L, Grenz A, Eltzschig HK, Blackburn MR, Kellems RE, Xia Y. Excess adenosine A2B receptor signaling contributes to priapism through HIF-1α mediated reduction of PDE5 gene expression. FASEB J. 2014 Jun;28(6):2725-35.

Ning C, Qi L, Wen J, Zhang Y, Zhang W, Wang W, Blackburn M, Kellems R, Xia Y. Excessive penile norepinephrine level underlies impaired erectile function in adenosine A1 receptor deficient mice. J Sex Med. 2012 Oct;9(10):2552-61.

Wen J, Xia Y. Adenosine signaling: good or bad in erectile function?Arterioscler Thromb Vasc Biol. 2012 Apr;32(4):845-50.

Jiang X, Li D, Yang J, Wen J, Chen H, Xiao X, Dai Y, Yang J, Tang Y. Characterization of a novel human testis-specific gene: testis developmental related gene 1 (TDRG1). Tohoku J Exp Med. 2011 Dec;225(4):311-8.

Wen J, Grenz A, Zhang Y, Dai Y, Kellems RE, Blackburn MR, Eltzschig HK, Xia Y. A2B adenosine receptor contributes to penile erection via PI3K/AKT signaling cascade-mediated eNOS activation. FASEB J. 2011 Aug;25(8):2823-30.

Wen J, Dai Y, Zhang Y, Zhang W, Kellems RE, Xia Y. Impaired erectile function in CD73-deficient mice with reduced endogenous penile adenosine production. J Sex Med. 2011 Aug;8(8):2172-80.

Dai Y, Zhang W, Wen J, Zhang Y, Kellems RE, Xia Y. A2B adenosine receptor-mediated induction of IL-6 promotes CKD. J Am Soc Nephrol. 2011 May;22(5):890-901.

Zhang Y, Dai Y, Wen J, Zhang W, Grenz A, Sun H, Tao L, Lu G, Alexander DC, Milburn MV, Carter-Dawson L, Lewis DE, Zhang W, Eltzschig HK, Kellems RE,Blackburn MR, Juneja HS, Xia Y. Detrimental effects of adenosine signaling in sickle cell disease. Nat Med. 2011 Jan;17(1):79-86.

Phatarpekar PV, Wen J, Xia Y. Role of adenosine signaling in penile erection and erectile disorders. J Sex Med. 2010 Nov;7(11):3553-64.

Wen J, Jiang X, Dai Y, Zhang Y, Tang Y, Sun H, Mi T, Kellems RE, Blackburn MR, Xia Y. Adenosine deaminase enzyme therapy prevents and reverses the heightened cavernosal relaxation in priapism. J Sex Med. 2010 Sep;7(9):3011-22.

Wen J, Jiang X, Dai Y, Zhang Y, Tang Y, Sun H, Mi T, Phatarpekar PV, Kellems  RE, Blackburn MR, Xia Y. Increased adenosine contributes to penile fibrosis, a dangerous feature of priapism, via A2B adenosine receptor signaling. FASEB J. 2010 Mar;24(3):740-9.

Zhou CC, Irani RA, Zhang Y, Blackwell SC, Mi T, Wen J, Shelat H, Geng YJ, Ramin SM, Kellems RE, Xia Y. Angiotensin receptor agonistic autoantibody-mediated tumor necrosis factor-alpha induction contributes to increased soluble endoglin production in preeclampsia. Circulation. 2010 Jan 26;121(3):436-44.


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