Wei Qichun, M.D., Ph.D.

Position:Chair of Radiation Oncology

Department:Radiation Oncology

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Chief Physician


As a professor in Radiation Oncology, Dr. Wei mainly focuses on the diagnosis and therapy of CNS tumors, head and neck cancer, including nasopharyngeal carcinoma. Special attention is also given to Hepatobiliary & Pancreatic cancer. His current research interests are focused on boron neutron capture therapy (BNCT), tumor radiosensitization through drug delivery vehicle, such as nanomicelles and liposomes; and tumor immunotherapy research, combined with radiation, with aims to achieve cure with minimized side-effect and to explore suitable targets.

With the good radiotherapy facilities equipped, intensive modulated radiotherapy (IMRT) and SBRT are performed as a routine in the department. The aim of using radiation is to achieve cure with the preservation of normal anatomy and function, or, when cure is not possible, to maximize palliation.

Appointment

Clinical / Research Interests

Radiation therapy for head & neck cancer and brain tumors, hepato-biliary-pancreatic, GI cancers, breast cancer. 

Professional Highlights

Member, Chinese Society of Therapeutic Radiation Oncology (CSTRO)

Director, Committee of Therapeutic Radiation Oncology, Zhejiang Anti-Cancer Association

Professional Appointments

Education Experience

Research Summary

Dr. Wei focuses on tumor radiosensitization, targeting therapy, and high precision radiotherapy (IGRT, IMRT, SBRT) for head & neck cancer and brain tumors, hepato-biliary-pancreatic, GI cancers, breast cancer. 

Publications

Tian Q, Jiang L, Dai D, Liu L, Shi X, Guo Y, Wu D, Yang J, Xu J, Cai Z, Ye Z, Xi Y, Zheng Z, Li H, Shui Y, Liu Y, Shang J, Wei S, Wei Q*  Impact of Postoperative Radiotherapy on the Prognosis of Early-Stage (pT1-2N0M0) Oral Tongue Squamous Cell Carcinoma. .J Clin Oncol. 2024 Apr 1:JCO2301106. doi: 10.1200/JCO.23.01106. Online ahead of print.

Chen H*, Shui Y, Tan Y, Dai D, Chen L, Jiang K, Wei Q*. Bridging Gaps in Oncology Nutrition Education and Teaching: A Comprehensive Analysis of Resident Physicians in China. J Cancer Educ. 2024 Apr 16. doi: 10.1007/s13187-024-02434-9. Online ahead of print.

Yang J, Shui Y, Liu L, Yu G, Wei Q*. Insights into treatment for hepatocellular carcinoma with tumor thrombus in the inferior vena cava or right atrium. Hepatobiliary Surg Nutr. 2024 Feb 1;13(1):168-171. doi: 10.21037/hbsn-23-619. Epub 2024 Jan 16.

Li C, Chen H, Zhang B, Fang Y, Sun W, Wu D, Su Z, Shen L, Wei Q. Radiomics Signature Based on Support Vector Machines for the Prediction of Pathological Complete Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer. Cancers (Basel). 2023 Oct 25;15(21):5134. doi: 10.3390/cancers15215134.

Yang X, Li P, Zhuang J, Wu Y, Qu Z, Wu W, Wei Q*. Identification of Molecular Targets of Bile Acids Acting on Colorectal Cancer and Their Correlation with Immunity. Dig Dis Sci. 2024 Jan;69(1):123-134. doi: 10.1007/s10620-023-08032-x. Epub 2023 Nov 2.

Yu Y, Chen H, Tian Z, Zhang Q, Shui Y, Shen L, Hu Q, Huang Z, Zhu S, Jiang H, Wei Q*. Improved survival outcome with not-delayed radiotherapy and immediate PD-1/PD-L1 inhibitor for non-small-cell lung cancer patients with brain metastases. J Neurooncol. 2023 Oct;165(1):127-137. doi: 10.1007/s11060-023-04459-4. Epub 2023 Oct 17.

Dai D, Wu D, Ni R, Li P, Tian Z, Shui Y, Hu H, Wei Q*. Novel insights into the progression and prognosis of the calpain family members in hepatocellular carcinoma: a comprehensive integrated analysis. Front Mol Biosci. 2023 Jul 12;10:1162409. doi: 10.3389/fmolb.2023.1162409. eCollection 2023.

Yang X, Li P, Qu Z, Zhuang J, Wu Y, Wu W, Wei Q*. Gut bacteria and sex differences in colorectal cancer. J Med Microbiol. 2023 Jun;72(6). doi: 10.1099/jmm.0.001706.

Guo S, Yao Y, Tang Y, Xin Z, Wu D, Ni C, Huang J*, Wei Q*, Zhang T*. Radiation-induced tumor immune microenvironments and potential targets for combination therapy. Signal Transduct Target Ther. 2023 May;8(1):205. doi: 10.1038/s41392-023-01462-z.

Yang Q, Dai Q, Bao X, Zhou Y, Lu Y, Zhong H, Wu L, Guo Y, Liu L, Tan X, Xia Y, Han M*, Wei Q*. Evaluation of a Tumor-Targeting Oligosaccharide Nanosystem in BNCT on an Orthotopic Hepatocellular Carcinoma Model. Mol Pharm. 2023 Feb 6;20(2):1025-1038

Yang X, Wei Q*. Identification of a novel Immune-Related prognostic model for patients with colorectal cancer based on 3 subtypes. Immunobiology . 2023 Feb 14;228(2):152352

Dai D, Liu L, Guo Y, Shui Y, Wei Q*. A Comprehensive Analysis of the Effects of Key Mitophagy Genes on the Progression and Prognosis of Lung Adenocarcinoma. Cancers (Basel). 2022 Dec 22;15(1):57

Dai D, Tian Q, Yu G, Shui Y, Jiang H, Wei Q*. Severe Radiation-Induced Lymphopenia Affects the Outcomes of Esophageal Cancer: A Comprehensive Systematic Review and Meta-Analysis. Cancers (Basel). 2022 Jun 20;14(12):3024

Zhang C, Zhang W, Shui Y, Li P, Tian Z, Duan S, Wei Q*. Implications of m6A-associated snRNAs in the prognosis and immunotherapeutic responses of hepatocellular carcinoma. Front Immunol. 2022 Nov 2;13:1001506

Jiejian Chen#&, Qi Dai&, QiYao Yang&, Xiaoyan Bao, Yi Zhou, Haiqing Zhong, Linjie Wu, Tiantian Wang, Zhicheng Zhang, Yiying Lu, Zhentao Zhang, Mengting Lin, Min Han*, Qichun Wei*, Therapeutic nucleus-access BNCT drug combined CD47-targeting gene editing in glioblastoma., Journal of Nanobiotechnology, 2022.03, 20, ,102-

Jiejian Chen#&, Qiyao Yang&, Minchen Liu, Mengting Lin, Tiantian Wang, Zhentao Zhang, Xincheng Zhong, Ningning Guo, Yiying Lu, Jing Xu&, Changsheng Wang, Min Han*, Qichun Wei*, Remarkable Boron Delivery Of iRGD-Modified Polymeric Nanoparticles For Boron Neutron Capture Therapy, International Journal of Nanomedicine, 2019.10, 14, 8161-8177

Xu J, Wang J, Wei Q. Boron neutron capture therapy in clinical application:Progress and prospect. Chin Sci Bull, 2021;67(14):1479-1489.

Lihong Liu#&, Yongjie Shui#&, Qianqian Yu&, Yinglu Guo&, Lili Zhang&, Xiaofeng Zhou&, Risheng Yu, Jianying Lou, Shumei Wei*, Qichun Wei*, Narrow-Margin Hepatectomy Resulted in Higher Recurrence and Lower Overall Survival for R0 Resection Hepatocellular Carcinoma, Frontiers in oncology, 2021.01, 10,

Lin Zheng#&, Zhi-Rui Zhou#, QianQian Yu#&, Minghan Shi, Yang Yang&, Xiaofeng Zhou&, Chao Li, Qichun Wei*, The Definition and Delineation of the Target Area of Radiotherapy Based on the Recurrence Pattern of Glioblastoma After Temozolomide Chemoradiotherapy, Frontiers in oncology, 2021.02, 10,

Yang Yang#&, Mengyuan Chen, Jiping Xie, Yongling Ji, Liming Sheng, Guoqin Qiu, Xianghui Du, Qichun Wei*, Treatment Patterns and Outcomes of Elderly Patients With Potentially Curable Esophageal Cancer, Frontiers in oncology, 2022.02, 12,

Yongjie Shui#&, Wei Yu&, Xiaoqiu Ren&, Yinglu Guo&, Jing Xu&, Tao Ma, Bicheng Zhang&, Jianjun Wu, Qinghai Li, Qiongge Hu, Li Shen&, Xueli Bai, Tingbo Liang, Qichun Wei*, Stereotactic body radiotherapy based treatment for hepatocellular carcinoma with extensive portal vein tumor thrombosis, Radiation Oncology, 2018.09, 13, 1, 188-

Zhijun Yuan#&, Yongjie Shui&, Lihong Liu&, Yinglu Guo&, Qichun Wei*, Postoperative recurrent patterns of gallbladder cancer: possible implications for adjuvant therapy, Radiation Oncology, 2022.07, 17, 1, 118

Wei Yu#&, Chunxiu Hu&, Yongjie Shui&, Kui Wu, Lili Zhang&, Ying Chen, Chao Li, Jing Xu&, Qichun Wei*, Failure patterns after curative resection for intrahepatic cholangiocarcinoma: possible implications for postoperative radiotherapy, BMC Cancer, 2019.11, 19, 1, 1108-

Jing Xu#&, Li Shen&, Yongjie Shui&, Wei Yu&, Qingqu Guo, Risheng Yu, Yulian Wu, Qichun Wei*, Patterns of recurrence after curative D2 resection for gastric cancer: Implications for postoperative radiotherapy, Cancer Medicine, 2020.07, 9, 13, 4724-4735

Qi Dai#&, QiYao Yang&, Xiaoyan Bao, Jiejian Chen&, Min Han*, Qichun Wei*, The Development of Boron Analysis and Imaging in Boron Neutron Capture Therapy (BNCT), Molecular Pharmaceutics, 2022.01, 19, 2, 363-377

Dongjun Dai#&, Qiaoying Tian#&, Yongjie Shui&, Jinfan Li*, Qichun Wei*, The impact of radiation induced lymphopenia in the prognosis of head and neck cancer: A systematic review and meta-analysis, Radiotherapy and Oncology, 2022.03, 168, , 28-36

Dongjun Dai#&, Qiaoying Tian#&, Genhua Yu&, Yongjie Shui&, Hao Jiang*, Qichun Wei*, Severe Radiation-Induced Lymphopenia Affects the Outcomes of Esophageal Cancer: A Comprehensive Systematic Review and Meta-Analysis, Cancers (Basel), 2022.07, 14, 12, 3024

Wei Yu#&, Anwen Shao, Xiaoqiu Ren&, Zexin Chen, Jinghong Xu, Qichun Wei*, Comparison of Immune Checkpoint Molecules PD-1 and PD-L1 in Paired Primary and Recurrent Glioma: Increasing Trend When Recurrence, Brain Sciences, 2022.02, 12, 2, 266

Lin Zheng#&, Zhi-Rui Zhou, Minghan Shi, Haiyan Chen&, Qian-Qian Yu&, Yang Yang&, Lihong Liu&, Lili Zhang&, Yinglu Guo&, Xiaofeng Zhou&, Chao Li, Qichun Wei*, Nomograms for predicting progression-free survival and overall survival after surgery and concurrent chemoradiotherapy for glioblastoma: a retrospective cohort study, Annals of Translational Medicine, 2021.04, 9, 7,

Haiyan Chen#&, Chao Li, Lin Zheng&, Wei Lu, Yanlin Li, Qichun Wei*, A machine learning-based survival prediction model of high grade glioma by integration of clinical and dose-volume histogram parameters, Cancer Medicine, 2021.04, 10, 8, 2774-2786

Wei Yu#, Xiaoqiu Ren&, Chunxiu Hu, Yinuo Tan, Yongjie Shui&, Zexin Chen, Lili Zhang&, Jiaping Peng, Qichun Wei*, Glioma SOX2 expression decreased after adjuvant therapy, BMC Cancer, 2019.11, 19, 1

Chen J, Yang Q, Liu M, Lin M, Wang T, Zhang Z, Zhong X, Guo N, Lu Y, Xu J, Wang C, Han M, Wei Q. Remarkable Boron Delivery Of iRGD-Modified Polymeric Nanoparticles For Boron Neutron Capture Therapy. Int J Nanomedicine, 2019;14:8161-8177.

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