Department：Geriatrics
Medical School：Zhejiang University School of Medicine, China
Academic Rank：Associate Chief Physician
Diagnosis, treatment and management of chronic diseases in the elderly patients.
Member, Preventive Health Care Group, Health Management Branch, Chinese Medical Association
Standing Committee Member, Nutrition Branch, Rehabilitation Society, Zhejiang Medical Association
Member, Osteoporosis Branch, Zhejiang Medical Association
Dr. Jin's previous studies confirmed that curcumin can inhibit ROS/NF-κB signaling pathway, reduce oxidative stress and inflammatory factor release, and promote autophagy. Recent studies confirmed that curcumin can regulate the activity of NLRP3 inflammasome by promoting autophagy, thus regulating cell pyrolysis, and ultimately protect the survival of endothelial cells in a high glucose environment. The mechanism of curcumin in regulating endothelial cell pyrolysis in diabetic angiopathy will provide an experimental basis for the treatment of diabetic vascular disease.
Qihui Jin, Yanhong Jiang, Lizhong Fu, et al. Wenxin Granule Ameliorates Hypoxia/Reoxygenation-Induced Oxidative Stress in Mitochondria via the PKC- δ/NOX2/ROS Pathway in H9c2 Cells. Oxid Med Cell Longev, 2020, 2020:3245483.
Jin QH, Shen HX, Wang H, et al. Curcumin improves expression of SCF/c-kit through attenuating oxidative stress and NF-κB activation in gastric tissues of diabetic gastroparesis rats. Diabetol Metab Syndr, 2013,5(1):12.
The role of ROS/NF-κB signaling pathway in curcumin regulation of autophagy and inhibition of hyperglycemia induced apoptosis of human umbilical vein endothelial cells. Funding Source: Chinese Medicine Research Program of Zhejiang Province.
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Zhejiang University School of Medicine
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