Wang Ben, M.D., Ph.D.

Department:Cancer Institute

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Associate Chief Professor


Clinical / Research Interests

Professional Highlights

Professional Appointments

Member, Chinese Society of Chemistry, 2015–present

Member, Chinese Society of Biomedical Engineering, 2015–present

Member, Zhejiang Biomedical Society, 2015–present

Member, Chinese Society of Cell Biology, 2016–present

Guest Editor, Current Topics in Medicinal Chemistry, 2015

Editorial Board Member, Journal of Bioelectronics and Nanotechnology, 2015–present

Editorial Board Member, Science Cronicon, 2015–present

Member, American Chemical Society , 2014–present 

Reviewer, ACS Applied Materials & Interfaces, 2012–present

Reviewer, ACS Nano, 2009–present

Reviewer, Angewandte Chemie International Edition, 2012–present

Reviewer, Biochemical Sciences, 2014–present

Reviewer, Cancer Letters, 2014–present

Reviewer, Colloids and Surfaces B, 2013–present

Reviewer, Current Pharmaceutical Design, 2010–present

Reviewer, Journal of Controlled Release, 2010–present

Reviewer, Journal of Crystal Growth, 2013–present

Reviewer, Journal of Physical Chemistry C, 2011–present

Reviewer, Journal of the American Chemical Society, 2013–present

Reviewer, Life Sciences, 2015–present

Reviewer, Microfluidics and Nanofluidics, 2012–present

Reviewer, Mini-reviews in Medicinal Chemistry, 2015–present

Reviewer, Nano Research, 2015–present

Reviewer, Oncology Letter, 2015–present

Reviewer, Scientific Reports, 2016–present

Reviewer, Stem Cell Translational Medicine, 2015–present

Education Experience

Research Summary

Dr. Wang (wanglab.zju.edu.cn) uses an interdisciplinary approach that integrates material science, biology, chemistry and engineering to solve problems in human health. It is emphasized that using Nature's design principles to develop bio-inspired materials and devices, and ultimately, transform medicine. From the physicochemical perspective, they are focused on understanding the molecular mechanisms involved in the interfaces of cell-cell, cell-materials, and develop the tools for cancer diagnosis and personalized medicine.


Publications

Zhao R, Wang B, Yang X, Xiao Y, Wang X, Shao C, Tang R*. A drug-free tumor therapy strategy: Cancer-cell-targeting calcification. Angew. Chem. Int. Ed. 2016, 55 (17), 5225-5229.

Rao Y, Chen W, Liang X, Huang Y, Miao J, Liu L, Lou Y, Zhang X, Wang B, Tang R, Chen Z, Lu X*. Epirubicin‐Loaded Superparamagnetic Iron-Oxide Nanoparticles for Transdermal Delivery: Cancer Therapy by Circumventing the Skin Barrier. Small 2015, 11 (2), 239-247.

Xiao Y, Zhou H, Xuan N, Cheng M, Luo Y, Wang B*, Tang R. Effective and selective cell retention and recovery from whole blood by electroactive thin films. ACS Appl. Mater. Interfaces 2014, 6 (23), 20804–20811.

Wang B*, Zhou H, Luo Y, Tang R, Zheng S. Biological interfacial engineering for metastatic cancer diagnosis and intervention. Curr. Med. Chem. 2014, 21 (22), 2510-2521.

Wang B#, Wang G#, Zhao B, Chen J, Zhang X, Tang R*. Antigenically shielded universal red blood cells by polydopamine-based cell surface engineering. Chem. Sci. 2014, 5 (9), 3463-3468.

Wang B*, Liu P, Liu Z, Pan H, Xu X, Tang R*. Biomimetic construction of cellular shell by adjusting the interfacial energy. Biotechnol. Bioeng. 2014, 111 (2), 386-395.

Wang B*, Cell Surface Engineering: Fabrication of Functional Nanoshells (Functional Multilayered Polyelectrolyte Assemblies on Biological Cells). Fakhrullin R, Choi I and Lvov Y (Ed.). The Royal Society of Chemistry (UK), 2014.

Liu Z, Xiao Y, Chen W, Wang Y, Wang B, Wang G, Xu X, Tang R*. Calcium phosphate nanoparticles primarily induce cell necrosis through lysosomal rupture: the origination of material cytotoxicity. J. Mater. Chem. B. 2014, 2 (22), 3480-3489.

Wang B, Tang R*. Biomineralization: one promising bridge between inorganic chemistry and biomedicine. Prog. Chem. 2013, 25 (4), 633-641.

Liu P, Chen Y, Wang G, Wang B, Xu X and Tang R*. Cell death induced by in situ mineralized calcium phosphate in growth microenvironment. Chinese J. Inorg. Chem. 2013, 29 (1), 89-94.

Coutinho D, Sant S, Shakiba M, Wang B, Gomes M, Neves N, Reis R, Khademhosseini A*. Microfabricated photocrosslinkable polyelectrolyte-complex of chitosan and methacrylated gellan gum. J. Mater. Chem. 2012, 22 (33), 17262-17271.

Xu X*, Wang B, Tang R. Hybrid materials that integrate living cells: Improved eco-adaptation and environmental applications. ChemSusChem 2011, 4 (10), 1439-1446.

Mahmoudi M*, Sant S, Wang B, Laurent S and Sen T. Superparamagnetic iron oxide nanoparticles (SPIONs): development, surface modification and applications in chemotherapy. Adv. Drug Deliver. Rev. 2011, 63 (1-2), 24-46.

He J, Du Y, Guo Y, Hancock MJ, Wang B, Shin H, Wu J, Li D, Khademhosseini A*. Microfluidic-based synthesis of composite materials with cross-gradient for screening cell-biomaterial interactions. Biotechnol. Bioeng. 2011, 108 (1), 175-185.

Wu J, Wheeldon I, Guo Y, Lu T, Du Y, Wang B, He J, Hu Y, Khademhosseini A*. A sandwiched microarray platform for benchtop cell-based high throughput screening. Biomaterials 2011, 32 (3), 841-848.

Xiao W, He J, Nichol JW, Wang L, Huston CB, Wang B, Du Y, Fan H, Khademhosseini A*. Synthesis and characterization of photocrosslinkable gelatin and silk fibroin interpenetrating network hydrogel. Acta Biomater. 2011, 7 (6), 2384-2393. 

Wang B#, Liu P# and Tang R*. Cellular shellization: Surface engineering gives cells an exterior. BioEssays 2010, 32 (8), 698-708.

Wang B, Liu P, Tang Y, Pan H, Xu X and Tang R*. Guarding embryo development of zebrafish by shell engineering: a strategy to shield life from ozone depletion. PLoS one 2010, 5 (4), e9963.

Du Y, Hancock MJ, He J, Villa-Uribe JL, Wang B, Cropek DM, Khademhosseini A*. Convection-driven generation of long-range material gradients. Biomaterials 2010, 31 (9), 2686-2694.

Hancock M, Du Y, He J, Villa-Uribe J, Wang B, Cropek D, Khademhosseini A*. Generating long material gradients by convection and alternating flow in a microchannel. Bioengineering Conference, Proceedings of the 2010 IEEE 36th Annual Northeast. 2010, 1-2.

Jiang W, Chu X, Wang B, Pan H, Xu X and Tang R*. Biomimetically triggered inorganic crystal transformation by biomolecules: A new understanding of biomineralization. J. Phys. Chem. B 2009, 113 (31), 10838-10844.

Wang B, Liu P, Jiang W, Pan H, Xu X and Tang R*. Yeast cells with an artificial mineral shell: Protection and modification of living cells by biomimetic mineralization. Angew. Chem. Int. Ed. 2008, 47 (19), 3560-3564.

Tao J, Pan H, Wang J, Wu J, Wang B, Xu X and Tang R*. Evolution of amorphous calcium phosphate to hydroxyapatite probed by gold nanoparticles. J. Phys. Chem. C 2008, 112 (38), 14929-14933.


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