Su Lida, M.D., Ph.D.

Position:Vice Chair of Neuro ICU

Department:Neuro ICU

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Chief Physician


Clinical / Research Interests

Rcovery of consciousness and coma

Multimodality brain monitoring

Cerebrovascular disease

Traumatic brain injury

Status epilepticus


Postoperative neurosurgery

Acute neuromuscular disorders

Donor maintenance

Professional Highlights

Youth Committee Member, Thrombosis and Hemostasis Committee, Zhejiang Medical Association, 2019-present

Youth Committee Member, Critical Care Branch, Chinese Research Hospital Association, 2019-present

Youth Committee Member, Neuroscience Branch, Chinese Research Hospital Association, 2015-present

Member, Neurocritical Care Society, USA, 2013-present 

Professional Appointments

Education Experience

Research Summary

Focus processed managements for the assessment, day-to-day therapy and treatment of neurocritical patients in various ICU settings.

Understanding the molecular mechanism of neuronal synaptic plasticity in the pathophysiology of neurocritical conditions.


Su LD*, Xu FX*, Wang XT, Cai XY, Shen Y. Cerebellar Dysfunction, Cerebro-cerebellar Connectivity and Autism Spectrum Disorders. Neuroscience. 2020;  May 23;S0306-4522(20)30323-7. Online ahead of print. (*co-first author)

Li DY, Bing YH, Chu CP, Cui X, Cui SB, Qiu DL*, Su LD*. Chronic Ethanol Consumption Impairs the Tactile-Evoked Long-Term Depression at Cerebellar Molecular Layer Interneuron-Purkinje Cell Synapses in vivo in Mice. Front Cell Neurosci. 2019;12:521. (*co-corresponding author)

Wang N, Hu YH, Su LD. Potassium channels-mediated electrophysiologic responses are inhibited by cytosolic phospholipase A2α ablation. Neuroreport. 2018;29(1):59-64. (corresponding author)

Chen J, He Y, Wu Y, Zhou H, Su LD, et al. Single Ethanol Withdrawal Regulates Extrasynaptic δ-GABA(A) Receptors Via PKCδ Activation. Front Mol Neurosci. 2018;11:141. 

Zhou L, Zhou L, Su LD, et al. Celecoxib Ameliorates Seizure Susceptibility in Autosomal Dominant Lateral Temporal Epilepsy. J Neurosci. 2018;38(13):3346-3357. 

Zhou JH, Wang XT, Zhou L, Zhou L, Xu FX, Su LD, et al. Ablation of TFR1 in Purkinje Cells Inhibits mGlu1 Trafficking and Impairs Motor Coordination, But Not Autistic-Like Behaviors. J Neurosci. 2017;37(47):11335-11352. 

Jiang NW, Wang DJ, Xie YJ, Zhou L, Su LD, et al. Downregulation of Glutamate Transporter EAAT4 by Conditional Knockout of Rheb1 in Cerebellar Purkinje Cells. Cerebellum. 2016;15(3):314-21.  

Su LD, Xie YJ, Zhou L, Shen Y, Hu YH. LG is involved in the development of mouse brain. Cerebellum. 2015;14(1):12-4.

Wang DJ, Su LD, Wang YN, et al. Long-term potentiation at cerebellar parallel fiber-Purkinje cell synapses requires presynaptic and postsynaptic signaling cascades. J Neurosci. 2014;34(6):2355-64. 

Wang Z, Wang YN, Sun CL, Yang D, Su LD,et al. C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICK1-PKCα complex and cerebellar plasticity. PLoS One. 2013;8(12):e83862. 

Shao CY, Zhu J, Xie YJ, Wang Z, Wang YN, Wang Y, Su LD,et al. Distinct functions of nuclear distribution proteins LIS1, Ndel1 and NudCL in regulating axonal mitochondrial transport. Traffic. 2013;14(7):785-97. 

Zou N, Wu X, Jin YY, He MZ, Wang XX, Su LD, et al. ATP regulates sodium channel kinetics in pancreatic islet beta cells. J Membr Biol. 2013;246(2):101-7. 

Dai Q, Su L. Neurogenic pulmonary edema caused by spontaneous cerebellar hemorrhage: A fatal case report. Surg Neurol Int. 2014;5:103. (corresponding author)

Su LD, Wang DJ, Yang D, Shen Y, Hu YH. Retrograde cPLA2α/arachidonic acid/2-AG signaling is essential for cerebellar depolarization-induced suppression of excitation and long-term potentiation. Cerebellum. 2013;12(3):297-9. 

Ge F*, Yuan S*, Su L*,et al. Alteration of innate immunity by donor IL-6 deficiency in a presensitized heart transplant model. PLoS One. 2013;8(10):e77559. (*co-first author)

Wang DJ*, Yang D*, Su LD*, et al. Cytosolic phospholipase A2 alpha/arachidonic acid signaling mediates depolarization-induced suppression of excitation in the cerebellum. PLoS One. 2012;7(8):e41499. (*co-first author)

Sun CL, Su LD, Li Q, Wang XX, Shen Y. Cerebellar long-term depression isdeficient in Niemann-Pick type C disease mice. Cerebellum. 2011;10(1):88-95.

Su LD, Sun CL, Shen Y. Ethanol Acutely Modulates mGluR1-dependent Long-Term Depression in Cerebellum. Alcohol Clin Exp Res. 2010;34(7):1140-5.

Su LD, Shen Y. Blockade of glutamate transporters facilitates cerebellar synaptic long-term depression. Neuroreport. 2009;20(5):502-7.

Current Program

Mechanisms of arachidonic acid metabolism regulating synaptic plasticity of Purkinje cells in sepsis-related encephalopathy. Funding Source: National Natural Science Foundation of China.

Modulatory function of cPLA2α/arachidonic acid in cerebellar long-term plasticity. Funding Source: National Natural Science Foundation of China.

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