Shi Yuping, M.D., Ph.D.

Department:Cardiology

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Chief Physician


Appointment

Clinical / Research Interests

Coronary intervention

Risk factor of coronary disease

Molecular genetics in coronary heart disease

Cadiac pacing 

Professional Highlights

Zhejiang Scientific and Technological Progress Award, Second Prize

Professional Appointments

Education Experience

Research Summary

Publications

Haibo Liu a, Xiaofang Guo, Yuping Shi. Congenital absence of the right coronary artery with superdominant left circumflex coronary artery. International Journal of Cardiology 2012, 158: e13–e14.

Lequan Qiua, Yuping Shi, Weihong Zhong, Coenzyme Q10 production by immobilized Sphingomonas sp. ZUTE03 via a conversion–extraction coupled process in a three-phase fluidized bed reactor. Enzyme and Microbial Technology 2012,50: 137–142.

Lei Zhao, Yuping Shi, Weihong Zhong Nicotine degradation enhancement by Pseudomonas stutzeri ZCJ during aging process of tobacco leaves. World J Microbiol Biotechnol 2012, 28:2077–2086

LIU Hai bo, GUO Xiao-fang, SHI Yu ming. Prognostic value of serum concentration of heart-type fatty acid-binding protein on acute coronary syndrome at early stage. Chinese Journal of Pathophysiology 2011,27( 2): 238-242.

SHI Yu-ping, GONG Hua-lan, WANG Jian-an Association of thrombospondin-1 gene N700S polymorphism with coronary artery disease. Journal of Zhejiang University Medicine Sciences 2011, 40(4): 1008-9292.

MA JB, LI H, SHI YP, et al. Association of chymase gene polymorphism with diabetic nephropathy in type 2 diabetes. Zhejiang Medical Journal 2009, 31(4):414-416LIU HB, SHI YP. 

Haptoglobin polymorphism and coronary artery disease. International Journal of Cardiovascular Disease, 2008;35(1): 19-22.

JIN XL, SHI YP, PAN J, et al. Differential proteomic analysis of liver in apoE/LDLR double-gene mutant mice. Chinese Journal of Pathophysiology, 2007, 23 (10): 1959-1963.

SHI YP, MENG WH, SHAN J, et al. Angiotensin converting enzyme polymorphism in Chinese han populations and relevance to the severity of coronary atherosclerosis. Journal of Zhejiang University Medicine Sciences 2006; 35(3): 287-291.

LIU HB, SHI YP. Lipoprotein A-V regulating role of blood lipid. International Cardiovascular Journal. 2006; 33(2): 107-109.

Li ZY, SHI YP, SHAN J. ACE gene deletion polymorphism in patients with dilated cardiomyopathy with left ventricular heart function and expand the clinical relevance. Chinese Research magazine 2006; 12 (8): 1019-1020.

NIE WC, FU GS, SHI YP et al.Relationship between serum concentrations of IL-18, IL-10, IL-6 and acute coronary syndrome. Chinese Journal of Pathophysiology 2005, 21(5) :886-888.

Sun Xia, SHI Yuping, PAN et al. ApoE-/-/LDLR-/-/Leprdb/db mice on high-fat and high-cholesterol diet, the effects of the differences in gene expression in liver tissues. China pathophysiological magazine 2005.11.15; 21 (11) : 2225-2228.

JIN XL, SUN WX, SHI YP et al. Study on differentially expressed gene of the liver of treble fatty metabolism genes mutant mice using cDNA microarray. Chinese Journal of Medical Genetics 2005;22(1): 27-30.

Jinxiaolei, SHI Yuping et al. Lipid metabolism-related genes mutant mouse liver gene expression studies. Chinese Journal of Medical Genetics 2005; 22 (1) : 27-30.

CAI SY; XU G; SHI YP et al. Association of the angiotensin-converting enzyme and angiotensinogen gene polymorphism with left ventricular hypertrophy in hypertension. Journal of Emergency Medicine 2005, 14(4): 323-327.

CAI SY; XU G; SHI YP et al. Association of angiotensinogen gene M235T variant with hypertrophic cardiomyopathy. Chinese Journal of Medical Genetics 2004; 21(3): 280-282.

TANG OS, XU G, SHI YP et al .Lack of association between the 4ba gene polymorphism of the endothelial nitric oxidesynthase gene and the risk of premature coronary artery disease. South China Journal of Cardiovascular Diseases 2004;10(4):293-2962004; 10(4): 293-296.

CAI SY, YU F, SHI YP et al. Association of angiotensinogen gene M235T variant with essential hypertension. Journal of Zhejiang Universit. Medicine Sciences 2004; 33(2): 151-154.

FENG BL, XU G, SHI YP et al. Association of F ⅩⅢ Val34Leu with coronary heart disease. Chinese Journal of Pathophysiology 2004; 20(10):1023-1826.

SUN WX, SHI YP, JIN XL, et al.The characteristics of atherosclerotic early lesion in treble lipid metabolism genes mutant mouse. Chinese Journal of Cardiology 2004;32(11):1019-1012.

JIN GD, XU G, SHI YP et al. Association of prothrombin G20210A and coagulation factor Leiden gene mutation with coronary heart disease. Chinese Journal of Pathophysiology 2003;19(7): 969-970, 1004.

XU G; JIN GD; SHI YP et al.The study of plasma C-reactive protein and the 1059G/C polymorphism in patients with acute coronary syndrome. Journal of Emergency Medicine 2003;12(4): 223-226.

TANG OS, XU G, SHI YP, et al. Lack of association between the 4ba gene polymorphism of the endothelial nitric oxidesynthase gene and the risk of coronary artery disease. Chinese Journal of Cardiology 2003; 31(3): 191. 

XU G, JIN GD, SHI YP et al. Plasma C-reactive protein level and the 1059G/C polymorphism of CRP in patients with coronary artery disease. Chin J Cardiol 2003;31(4): 274-277.

Ma Jiangbo, Zhou Wang, SHI Yuping. The lipids in type 2 diabetic patients with coronary heart disease changes. ZHEJIANG 2003; 5 (9): 684-685.

XU Geng, JIN Guodong, SHI Yuping, et al.Polymorphisms in the coagulation factor Ⅶ gene and the risk of myocardial infarction inpatients undergoing coronary angiography. Chin Med J 2003;116(8):1194-1197.

Li CJ, Xu G, SHI YP, et al. the total load on the risk of coronary heart disease and infection pathogens C-reactive protein in serum. China circulation magazine 2003; 18 (4) : 249.

Li CJ, Xu G, SHI YP, et al. equality. Serum C-reactive protein and coronary heart disease risk factors and the relationship between coronary artery disease. China circulation magazine 2003; 18 (6) : 443.

Shi YP, Shan J, Fu GS , Xu G, Ying SQ, Cai SY. Association between the angiotensin-converting enzyme gene polymorphism and ventricular arrhythmias in patients with acute myocardial infarction in Chinese Han nationality. Chin J Pathophysiology. 2002, 18(11): 1423-1442.

Wei DH, Shan J, Chan ZM, Shi YP. The G894T mutation of the endothelial nitric oxide synthase gene is associated with coronary atherosclerotic heart disease in Chinese. Chin J Med Genet, 2002, 19(6): 471-474.

Shi YP, Shan J. The Frontier of molecular genetics in coronary heart disease. Zhejiang Clin Med, 2002;4(1):1-2.

Shan J, Li ZY, Shi YP, Fu GS. Association of the genetic polymorphysim of angiotensin-converting enzyme gene and idiopathic dilated cardiomyopathy. Chin J Cardiol . 2001, 29(5): 286-288.

Shan J, Shi YP, Fu GS. The reartionship between angiotensin converting enzyme gene polymorphysim and risk factors for coronary heart disease. Chin J Epidemiol, 2000,21(3):208-211.

Shi YP, Shan J, Fu GS. Association of angiotensin converting enzyme gene polymorphysim with coronary heart diseases in Chinese. Chin J Intern Med. 1998,37(12):815-818.

Shi YP, Shan J, Fu GS. DNA polymorphism of angiotensin-converting enzyme gene in Chinese Han nationality. J ZheJiang Med Uni. 1998,27(4):158-160.

Pang XH, Fu GS, Shan J, Shi YP, Zhu Y. Effects of gingko extraction Egb761 on reperfusion arrhythmias in isolate rate heart.Chin Pharmo Bulletin.1998,14(3):283-284.

Xia SY, Qin GM, Shi YP. The clinical significance of blood PAI—1 activity level in patients with angina pectoris of coronary artery disease. Zhejiang Med,1998;20(11): 642-643.

Cheng G, Shan J, Ma J, Shi YP. Simvastatins induced apoptosis and its effect on apoptosis related gene expression in rat vascular smooth musle cell. J ZheJiang Uni (Med). 1998,27(4):158-160.

Zhu Y, Fu GS, Shi YP, er al. The protection effects of gingko extraction Egb761 on reperfusion injury in cats in vivo. Chin Pharm Bulletin. 1996;12(Suppl):16-18.


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