Shan Pengfei, M.D., Ph.D.

Position:Vice Chair of Endocrinology


Medical School:Central South University, Xiangya Medical School, China

Academic Rank:Chief Physician


Clinical / Research Interests

Metabolic syndrome


Diabetes Mellitus

Metabolic bone disease

Complicated diseases of Endocrinology, especially weight loss and intake control of type 2 diabetes mellitus

Professional Highlights

Professional Appointments

Lead Guest Editor, International Journal of Endocrinology, 2016-present

Vice Chair, Youth Committee, Zhejiang Society of Enodcrinology, 2015-present 

Guest Editor, International Journal of Endocrinology, 2013-2015

Education Experience

Research Summary


Shan PF, Ji XL, Wang L, Li P, Ren YZ. Comment on Tang et al. Effects of Insulin Glargine and Liraglutide Therapy on Liver Fat as Measured by Magnetic Resonance in Patients With Type 2 Diabetes: A Randomized Trial. Diabetes Care 2015;38:1339-1346. Diabetes Care. 2015 Sep;38(9):e148–9.

Yuan LQ, Ouyang HW, Andersen TL, Jiang Y, Pantano F, Shan PF. Osteoporosis 2014. Int J Endocrinol. 2015; 2015:567593. 

Shan PF, Ji XL. Comment on Lin et al. Risk Factors for Decline in IQ in Youth With Type 1 Diabetes Over the 12 Years From Diagnosis/Illness Onset. Diabetes Care 2015;38:236-242. Diabetes Care. 2015 Aug;38(8):e120.

Zou QL, Wei GN, Chen JX, Ye Q, Shan PF *.Hepatitis B virus-associated nephropathy in a patient with diabetes mellitus. J Diabetes Investig 2014;5(1):87–89.

Zheng J, Shan PF *, Gu W. The efficacy of metformin in pregnant women with polycystic ovary syndrome: a meta-analysis of clinical trials. J Endocrinol Invest 2013;36(10):797–802.

Zhu X, Jiang Y, Shan PF, Shen J, Liang QH, Cui RR, Liu Y, Liu GY, Wu SS, Lu Q, Xie H, Liu YS, Yuan LQ, Liao EY. Vaspin attenuates the apoptosis of human osteoblasts through ERK signaling pathway. Amino Acids, 44(3):961–968, 2013.

Shan PF, Xian CJ, Li M, Xiang GD, Yuan LQ. Osteoporosis. Int J Endocrinol. 2013;2013:952858.

Yin JH, Song ZY, Shan PF*, Xu J, Ye ZM, Xu XH, Zhang SZ, Liang Q, Zhao Y, Ren Z, Yu YP. Age- and gender-specific prevalence of carotid atherosclerosis and its association with metabolic syndrome in Hangzhou, China. Clin Endocrinol (Oxf), 76(6):802–809, 2012. (Corresponding author)

Shan PF, Lu Y, Cui RR, Jiang Y, Yuan LQ, Liao EY. Apelin Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells. PLoS One 2011, 6(3):e17938.

Shan PF, Wu XP, Zhang H, Cao XZ, Yuan LQ, Liao EY. Age-related bone mineral density, osteoporosis rate and risk of vertebral fracture in mainland Chinese women with type 2 diabetes mellitus. J Endocrinol Invest. 2011 Mar;34(3):190–196. 

Shan PF, Wu XP, Zhang H, Cao XZ, Gu W, Deng XG, Gu C, Liao EY. Bone mineral density and its relationship with Body mass index in postmenopausal women with type 2 diabetes mellitus in mainland China. J Bone Miner Metab 2009, 27:190–197. 

Gu W, Zou LX, Shan PF, Chen YD. Analysis of urinary proteomic patterns for diabetic nephropathy by ProteinChip. Protemics Clinical Applications 2008; 2: 744–750.

Wu XP, Hou YL, Zhang H, Shan PF, Zhao Q, Cao XZ, Dai RC, Luo XH, Liao EY. Establishment of BMD reference databases for the diagnosis and evaluation of osteoporosis in central southern Chinese men. J Bone Miner Metab. 2008;26(6):586-94. 

Tang SY, Shan PF, Xie H, Wu XP, Liao EY, Zhang H. Bone mineral content and bone mineral density at lumbar spine and forearm in Chinese girls aged 6-18 years. J Endocrinol Invest, 2007, 30(3): 205–209. 

Shan PF, Wu XP, Zhang H, Luo XH, Cao XZ, Xie H, Liu SP, Pi YZ, Fang TY, Liu H, Chen ZH, Zhong N, Liao EY. Age-related changes of serum bone alkaline phosphatase and cross-linked c-telopeptides of type I collagen and the relationship with bone mineral density in Chinese women. Clin Chim Acta, 2006, 366, 233–238. 

Luo XH, Guo LJ, Shan PF, Xie H, Wu XP, Zhang H, Cao XZ, Yuan LQ, Liao EY. Relationship of circulating MMP–2, MMP–1, and TIMP–1 levels with bone biochemical markers and bone mineral density in postmenopausal Chinese women. Osteoporos Int, 2006, 17: 521–526. 

Guo LJ, Luo XH, Wu XP, Shan PF, Zhang H, Cao XZ, Xie H, Liao EY. Serum concentrations of MMP-1, MMP-2, and TIMP-1 in Chinese women: Age-related changes, and the relationships with bone biochemical markers, bone mineral density. Clin Chim Acta, 2006, 371: 137–142. 

Wu XP, Dai RC, Shan PF, Yuan LQ, Cao XZ, Liao EY, Jiang Y. Establishment of BMD reference curves at different skeletal sites in women, using a Cartesian coordinate numeration system. Osteoporos Int, 2005, 16:1655–1662. 

Wu XP, Liao EY, Dai RC, Shan PF, Fang TY, Luo XH, Pi YZ, Jiang Y. Comparison of spine and femur reference data in native Chinese women from different regions of China. Osteoporos Int, 2005, 16:1215–1224. 

Zhong N, Wu XP, Xu ZR, Wang AH, Luo XH, Cao XZ, Xie H, Shan PF, Liao EY. Relationship of serum leptin with age, body weight, body mass index, and bone mineral density in healthy mainland Chinese women. Clin Chim Acta, 2005, 351:161–168. 

Wu XP, Liao EY, Zhang H, Shan PF, Cao XZ, Liu SP. Establishment of BMD reference plots and determination of peak BMD at multiple skeletal regions in mainland Chinese women and the diagnosis of osteoporosis. Osteoporos Int, 2004, 15:71–79. 

Wu XP, Liao EY, Zhang H, Dai RC, Shan PF, Cao XZ, Liu SP, Jiang Y. Relationship of body surface area with bone density and its risk of osteoporosis at various skeletal regions in women of mainland China. Osteoporos Int, 2004, 15:751–759. 

Wu XP, Liao EY, Zhang H, Dai RC, Shan PF, Cao XZ, Liu SP, Jiang Y. Determination of age-specific bone mineral density and comparison of diagnosis and prevalence of primary osteoporosis in Chinese women based on both Chinese and World Health Organization criteria. J Bone Miner Metab, 2004, 22:382–391.


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