Pan Zhijun, M.D., Ph.D.

Department:Orthopedics

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Chief Physician


Appointment

Clinical / Research Interests

Orthopedic trauma

Pelvic fracture

Fracture nonunion

Osteomyelitis

Professional Highlights

Zhejiang Medical and Health Science and Technology Innovation, First Prize

Professional Appointments

Member, Chinese Society of Orthopedics, Chinese Medical Association

Member, AO Trauma

Vice Chair, Zhejiang Society of Orthopedics, Chinese Medical Association 


Education Experience

Research Summary

Publications

Zhang W, Wang S, Yin H, Chen E, Xue D, Zheng Q, Gao X, Pan Z. Dihydromyricetin enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells in vitro partially via the activation of Wnt /β-catenin signaling pathway. Fundam Clin Pharmacol. 2016 Jul 29. doi: 10.1111/fcp.12225.

Zhou H, Wang G, Lu Y, Pan Z. Bio-inspired cisplatin nanocarriers for osteosarcoma treatment. Biomater Sci. 2016 Aug 19;4(8):1212-8. doi: 10.1039/c6bm00331a.

Lin F, Xue D, Xie T, Pan Z. HMGB1 promotes cellular chemokine synthesis and potentiates mesenchymal stromal cell migration via Rap1 activation. Mol Med Rep. 2016 Aug;14(2):1283-9.

Zhang W, Xue D, Yin H, Wang S, Li C, Chen E, Hu D, Tao Y, Yu J, Zheng Q, Gao X, Pan Z. Overexpression of HSPA1A enhances the osteogenic differentiation of bone marrow mesenchymal stem cells via activation of the Wnt/β-catenin signaling pathway. Sci Rep. 2016 Jun 9;6:27622. doi: 10.1038/srep27622.

Lin F, Zhang W, Xue D, Zhu T, Li J, Chen E, Yao X, Pan Z. Signaling pathways involved in the effects of HMGB1 on mesenchymal stem cell migration and osteoblastic differentiation. Int J Mol Med. 2016 Mar;37(3):789-97. doi:10.3892/ijmm.2016.2479.

Zhang W, Xue D, Yin H, Xie H, Ma H, Chen E, Hu D, Pan Z. Barbed versus traditional sutures for wound closure in knee arthroplasty: a systematic review and meta-analysis. Sci Rep. 2016 Jan 25;6:19764. doi: 10.1038/srep19764.

Zhang W, Lin F, Chen E, Xue D, Pan Z. Operative Versus Nonoperative Treatment of Displaced Intra-Articular Calcaneal Fractures: A Meta-Analysis of Randomized Controlled Trials. J Orthop Trauma. 2016 Mar;30(3):e75-81.

Wu Y, Chen L, Wang Y, Li W, Lin Y, Yu D, Zhang L, Li F, Pan Z. Overexpression of Sirtuin 6 suppresses cellular senescence and NF-κB mediated inflammatory responses in osteoarthritis development. Sci Rep. 2015 Dec 7;5:17602.

Chen E, Xue D, Zhang W, Lin F, Pan Z. Extracellular heat shock protein 70 promotes osteogenesis of human mesenchymal stem cells through activation of the ERK signaling pathway. FEBS Lett. 2015 Dec 21;589(24 Pt B):4088-96.

Zhang W, Xue D, Hu D, Xie T, Tao Y, Zhu T, Chen E, Pan Z. Secreted klotho protein attenuates osteogenic differentiation of human bone marrow mesenchymal stem cells in vitro via inactivation of the FGFR1/ERK signaling pathway. Growth Factors. 2015;33(5-6):356-65.

Zhang W, Liu A, Hu D, Xue D, Li C, Zhang K, Ma H, Yan S, Pan Z. Indwelling versus Intermittent Urinary Catheterization following Total Joint Arthroplasty: A Systematic Review and Meta-Analysis. PLoS One. 2015 Jul 6;10(7):e0130636.

Zhang W, Chen E, Xue D, Yin H, Pan Z. Risk factors for wound complications of closed calcaneal fractures after surgery: a systematic review and meta-analysis. Scand J Trauma Resusc Emerg Med. 2015 Feb 8;23:18.

Zhang W, Liu A, Hu D, Tan Y, Al-Aidaros M, Pan Z. Effects of the timing of tourniquet release in cemented total knee arthroplasty: a systematic review and meta-analysis of randomized controlled trials. J Orthop Surg Res. 2014 Dec 3;9:125.

Xue D, Li F, Chen G, Yan S, Pan Z. Do bisphosphonates affect bone healing? A  meta-analysis of randomized controlled trials. J Orthop Surg Res. 2014 Jun 5;9:45.

Hou Z, Shi J, Ye H, Pan Z. Treatment of unstable intertrochanteric fractures with percutaneous non-contact bridging plates. Int J Surg. 2014;12(5):538-43.

Tan Y, Li H, Zheng Q, Li J, Feng G, Pan Z. A modified posterolateral approach for Hoffa fracture. Eur J Orthop Surg Traumatol. 2014 Oct;24(7):1321-3.

Wang J, Li H, Zheng Q, Feng G, Li J, Pan Z. Distraction arthrolysis of posttraumatic elbow stiffness with a hinged external fixator. Orthopedics. 2012 Nov;35(11):e1625-30.

Qi Y, Wang Y, Yan W, Li H, Shi Z, Pan Z. Combined mesenchymal stem cell sheets and rhBMP-2-releasing calcium sulfate-rhBMP-2 scaffolds for segmental bone tissue engineering. Cell Transplant. 2012;21(4):693-705.

Wang Y, Wang X, Li H, Xue D, Shi Z, Qi Y, Ma Q, Pan Z. Assessing the character of the rhBMP-2- and vancomycin-loaded calcium sulphate composites in vitro and in vivo. Arch Orthop Trauma Surg. 2011 Jul;131(7):991-1001.

Tan Y, Wang X, Li H, Zheng Q, Li J, Feng G, Pan Z. The clinical efficacy of the vacuum-assisted closure therapy in the management of adult osteomyelitis. Arch Orthop Trauma Surg. 2011 Feb;131(2):255-9.

Xue D, Zheng Q, Li H, Qian S, Zhang B, Pan Z. Selective COX-2 inhibitor versus nonselective COX-1 and COX-2 inhibitor in the prevention of heterotopic ossification after total hip arthroplasty: a meta-analysis of randomised trials. Int Orthop. 2011 Jan;35(1):3-8.

Xue D, Zheng Q, Zong C, Li Q, Li H, Qian S, Zhang B, Yu L, Pan Z. Osteochondral repair using porous poly(lactide-co glycolide)/nano-hydroxyapatite hybrid scaffolds with undifferentiated mesenchymal stem cells in a rat model. J Biomed Mater Res A. 2010 Jul;94(1):259-70.

Xue D, Zheng Q, Li H, Qian S, Zhang B, Pan Z. Reamed and undreamed intramedullary nailing for the treatment of open and closed tibial fractures: a subgroup analysis of randomised trials. Int Orthop. 2010 Dec;34(8):1307-13.

Xue D, Zheng Q, Pan Z. Vibration may be a potential non-pharmacological treatment of osteoarthritis. Med Hypotheses. 2009 May;72(5):612.


Current Program

Find People

Search by Family Name

Find A Department

Search by Departments