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Han Bin, M.D.

Department：Orthopedics

Medical School：Zhejiang University School of Medicine, China

Academic Rank：Associate Chief Physician

Appointment

Clinical / Research Interests

Orthopedic sports medicine and adult reconstruction surgery, especially arthroscopic shoulder surgery.

Professional Highlights

Zhejiang Professional Award for Science and Technology Innovation, Second Prize, 2013

Professional Appointments

Education Experience

Research Summary

Matrix biology and biological regeneration of intervertebral disc and cartilage.

Publications

Bin Han, Kai Zhu, Fang-cai Li, Yu-xiang Xiao, Jie Feng, Zhongli Shi, Min Lin, Jun Wang, Qi-xin Chen. A simple disc degeneration model induced by percutaneous needle puncture in the rat tail. Spine (Phila Pa 1976). 2008 Aug 15;33(18):1925-34.

Bin Han, Hai-chao Wang, Hao Li, Yi-qing Tao, Cheng-zhen Liang, Fang-cai Li, Gang Chen, Qi-xin Chen. Nucleus Pulposus Mesenchymal Stem Cells in Acidic Conditions Mimicking Degenerative Intervertebral Discs Give Better Performance than Adipose Tissue-derived Mesenchymal Stem Cells. Cells Tissues Organs. 2014;199(5-6):342-52.

Bin Han, Fangcai Li, Gang Chen, Hao Li, Qixin Chen. Motion Preservation in Type II Odontoid Fractures Using Temporary Pedicle Screw Fixation: A Preliminary Study. Eur Spine J. 2015 Apr;24(4):686-93.


Current Program

Role and mechanism of BDNF-MAPK signaling pathway targeting ASIC2 in the tolerance of nucleus pulposus stem cells to the hypertonic microenvironment of degenerative intervertebral disc (PI). Funding Source: Natural Science Foundation of Zhejiang (LY18H060004), 2018-2020.

Mechanism of IGF-1 Regulating Directional Differentiation of Nucleus Pulposus Stem Cells into Nucleus Pulposus-like Phenotypes via Wnt Signaling Pathway (PI). Funding Source: Health Commission of Zhejiang Province (2018241121), 2018-2020.


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