Song Xiaoxiao, M.D., Ph.D.


Medical School:Zhejiang University School of Medicine, China

Academic Rank:Associate Chief Physician


Clinical / Research Interests

Type I and Type II diabetes mellitus, hypoglycemic conditions and insulin secreting tumors

Adrenal disorders including Cushing's disease, Addison's disease and pheochromocytoma as well as hyperaldosteronism and other disorders of mineral metabolism

Pituitary disorders including pituitary tumors, acromegaly, and diabetes insipidus

Thyroid disorders including Graves' disease and other forms of hyperthyrodism, thyroiditis, hypothyroidism, goiter, and thyroid tumors

Professional Highlights

Professional Appointments

Education Experience

Research Summary


Yang BY, Yu HX, Min J, Song XX. A novel mutation in gene of PRPS1 in a young Chinese woman with X-linked gout: a case report and review of the literature. Clin Rheumatol 2019 Nov Clin Rheumatol. 2019 Nov 26. [Epub ahead of print] (Corresponding author) 

Bao H, Yu P, Song X, Zhou Y, Zhu Y.The influence of home-based exercise on gestational diabetes: a meta-analysis of randomized controlled trials. J Matern Fetal Neonatal Med. 2019 Jan 9:1-6. 

Song X, Shen Y, Zhou Y, Lou Q, Han L, Ho JK, Ren Y.General  hyperpigmentation induced by Grave's disease: A case report.  Medicine (Baltimore). 2018 Dec;97(49):e13279. 

Xie W, Song X, Liu Z. Impact of dipeptidyl-peptidase 4 inhibitors on cardiovascular diseases. Vascul Pharmacol. 2018 Oct;109:17-26. 

Song X, Yang B, Qiu F, Jia M, Fu G. High glucose and free fatty  acids induce endothelial progenitor cell senescence via  PGC-1α/SIRT1 signaling pathway. Cell Biol Int. 2017,41(10):1146-1159. 

Guo S, Messmer-Blust AF, Wu J, Song X, Philbrick MJ, Shie JL, Rana JS, Li J.Role of A20 in cIAP-2 protection against tumor necrosis factor α (TNF-α)-mediated apoptosis in endothelial cells. Int J Mol Sci. 2014 Mar 3;15(3):3816-33. (Co-first author)

Yu XY, Zhao Y, Song XX, Song ZY. Association between non-alcoholic fatty liver disease and arterial stiffness in the non-obese, non-hypertensive, and non-diabetic young and middle-aged Chinese population. J Zhejiang Univ Sci B. 2014 Oct;15(10):879-87. 

Jia M, Yang B, Li Z, Shen H, Song X, Gu W. Computational analysis of functional single nucleotide polymorphisms associated with the CYP11B2 gene. PLoS One. 2014 Aug 7;9(8):e104311. (Co-corresponding author)

Jia M, Zhang H, Song X, Pang X, Ye W, Miao W, Gu W. Association of CYP11B2 polymorphisms with susceptibility to primary aldosteronism: a meta-analysis. Endocr J. 2013;60(7):861-70. (Co-corresponding author)

An X, Jin Y, Philbrick MJ, Wu J, Messmer-Blust A, Song X, Cully BL, He P, XuM, Duffy HS, Li J. Endothelial cells require related transcription enhancer factor-1 for cell-cell connections through the induction of gap junction proteins. Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):1951-9. 

Jin Y, Wu J, Song X, Song Q, Cully BL, Messmer-Blust A, Xu  M, Foo SY, Rosenzweig A, Li J. RTEF-1, an upstream gene of hypoxia-inducible factor-1α, accelerates recovery from ischemia. J Biol Chem. 2011 Jun 24;286(25):22699-705. 

Song X, Kusakari Y, Xiao CY, Kinsella SD, Rosenberg MA, Scherrer-Crosbie M, Hara K, Rosenzweig A, Matsui T. mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy. Am J Physiol Cell Physiol. 2010 Dec;299(6):C1256-66. 

Qiu F, Song X, Zheng H, Zhao Y, Fu G. Thymosin beta4 induces endothelial progenitor cell migration via PI3K/Akt/eNOS signal transduction pathway. J Cardiovasc Pharmacol. 2009 Mar;53(3):209-14. 

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