Yin Xinzhen, M.D.


Medical School:Zhejiang University School of Medicine, China

Academic Rank:Associate Chief Physician


Clinical / Research Interests

Diagnosis and treatment of neurodegenerative diseases and cerebrovascular diseases, especially Parkinson's disease, motor neuron disease and hereditary cerebrovascular disease.

Professional Highlights

Professional Appointments

Education Experience

Research Summary

Focus on the pathogenesis of CADASIL and the transdifferentiation of dopaminergic neurons.


Yin Xinzhen, Zhou Ying, Yan Shenqiang, Lou Min. Effects of Cerebral Blood Flow and White Matter Integrity on Cognition in CADASIL Patients, Front. Psychiatry, 2019.1.14, 9(741): 1~6.

Yin Xinzhen, Wu Jimin, Song Shuijiang, Zhang Baorong, Chen Yanxing. Cerebral infarcts associated with adenomyosis: a rare risk factor for stroke in middle-aged women: a case series., BMC Neurology, 2018.12.19, 18(213): 1~4.

Chen Sheng, Ni Wang, Yin Xinzhen, Liu Hanqiu, Lu Cong, Zheng Qianjuan, Xu Yongfeng, Wu Lei, Zhang Liang, Wang Ning, Li Hongfu, Wu Zhiying. Clinical features and mutation spectrum in Chinese patients with CADASIL: A multicenter retrospective study, CNS Neurosci Ther, 2017, 23(9): 707~716.

Yin Xinzhen, Wu Dingwen, Wan Jinping, Yan Shenqiang, Lou Min, Zhao Guohua, Zhang Baorong. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: Phenotypic and mutational spectrum in patients from mainland China. International Journal of Neuroscience, 2014.9.1, 125(8): 585~592.

Yin Xinzhen, Ding Meiping, Zhang Baorong, Liu Jianren, Zhang Liang,Wang Peizhen, Zhou Fuyou, Zhao Guohua. Report of two Chinese families and a review of Mainland Chinese CADASIL patients, Journal of the Neurological Sciences, 2009.4.15, 279(1-2): 88~92.

Current Program

The mechanism of human celebral pericyte dysfunction caused by CADASIL related mutatant Notch3 receptor. Funding Source: National Natural Science Foundation of China.

Direct conversion of human fibroblasts to dopaminergic neurons and replacing dopamine neurons in PD rats. Funding Source: Natural Science Foundation of Zhejiang.

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