Jiang Lifeng, M.D., Ph.D.

DepartmentOrthopaedics

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Associate Chief Physician

Appointment

Clinical / Research Interests

Joint Surgery like degenerative arthritis/DDH/femoral head necrosis; sports Medicine like cartilage/meniscus/ligament/shoulder injury.

Professional Highlights

Excellent Teacher, The Second Affiliated Hospital Zhejiang University School of Medicine

Professional Appointments

Reviewer, International Journal of Molecular Medicine and Molecular Medicine Reports

Education Experience

Research Summary

Study on the pathogenesis and treatment of osteoarthritis

Research on the role of adipokines and cytokines in osteoarthritis

Cytoskeletal remodeling of chondrocyte in osteoarthritis

Publications

Jiang L, Bao J, Zhou X, Xiong Y and Wu L. Increased serum levels and chondrocyte expression of nesfatin-1 in patients with osteoarthritis and its relation with BMI, hsCRP, and IL-18. Mediators of inflammation 2013; 2013: 631251-631251.

Jiang L, Li H, Xin Z and Wu L. Computed tomography angiography and magnetic resonance imaging performance of acute segmental single compartment syndrome following an Achilles tendon repair: A case report and literature review. Chin J Traumatol 2016; 19: 290-294.

Jiang L, Li J, Zhou X, Bao J and Wu L. Paeonol inhibits IL-1 beta induced expression of iNOS, COX-2, and MMPs through NF-kappa B activation: an in vitro and in vivo study. International Journal of Clinical and Experimental Medicine 2017; 10: 10010-10020.

Jiang L, Zhang H, Chen H and Wu Q. Kyphotic Angle of the Motion Segment Most Accurately Predicts Injury to the Ligamentous Complex on Computed Tomography Scan of Thoracolumbar Fractures. World Neurosurg 2018; 118: e405-e413.

Jiang L, Zhou X, Xiong Y, Bao J, Xu K and Wu L. Association between interleukin-17A/F single nucleotide polymorphisms and susceptibility to osteoarthritis in a Chinese population. Medicine (Baltimore) 2019; 98: e14944.

Jiang L, Cao L, Fang J, Yu X, Dai X and Miao X. Ochronotic arthritis and ochronotic Achilles tendon rupture in alkaptonuria: A 6 years follow-up case report in China. Medicine (Baltimore) 2019; 98: e16837.

Jiang L, Fang J, Wu L. Role of infrapatellar fat pad in pathological process of knee osteoarthritis: Future applications in treatment. World J Clin Cases 2019; 7(16): 2134-2142.

Zhou X, Jiang L, Fan G, Yang H, Wu L, Huang Y, Xu N and Li J. Role of the ciRS-7/miR-7 axis in the regulation of proliferation, apoptosis and inflammation of chondrocytes induced by IL-1beta. Int Immunopharmacol 2019; 71: 233-240. (co-first author)

Jiang L, Xu K, Li J, Zhou X, Xu L, Wu Z, Ma C, Ran J, Hu P, Bao J, Wu L and Xiong Y. Nesfatin-1 suppresses interleukin-1β-induced inflammation, apoptosis, and cartilage matrix destruction in chondrocytes and ameliorates osteoarthritis in rats. Aging 2020; 12: 1760-1777.


Current Program

Effect and mechanism of nesfatin-1 on RhoA / ROCK signaling pathway in cytoskeletal remodeling of chondrocyte in osteoarthritis. Funding Source: National Natural Science Foundation of China.

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