Medical School：Zhejiang University School of Medicine, China
Public health and preventive medicine;
Epidemiology, especially molecular cancer epidemiology;
Managerial epidemiology and environmental (spatial) epidemiology.
Special Government Allowances of the State Council, 1993-Present
Wu Jieping Prize for Medical Research, 2006
China Epidemiology Excellence Award, 2009
State Scientific and Technological Progress Award, Second Prize
Ministry of Education's Scientific and Technological Progress Award, First Prize
Zhejiang Scientific and Technological Progress Award, First Prize
Committee Member, Steering Committee for Preventive Medical Education in Colleges and Universities
Vice Chair, Zhejiang Society of Health and Economic
Vice Chair, Community Physician Society, Zhejiang Medical Doctors Association
Associate Editor, Preventive Medicine
Editorial Board Member, Chinese Journal of Preventive Medicine
Editorial Board Member, Chinese Journal of Epidemiology
Prof. Chen has been engaged in research of epidemiology, public health and preventive medicine for more than 30 years.
1. Cancer epidemiology. He mainly studies the mechanism and effect of genetic and epigenetic factors, environmental exposure and their interactions in the pathogenesis of colorectal cancer, evaluate and determine the biomarkers, and further predict susceptible population.
2. Managerial epidemiology. Based on the evidence-based medicine and public health theory, he focused on the planning and decision-making of rural health care, construction of rural public health service system, evaluation of elderly health insurance and aging, and medical data management and analysis.
3. Combined with the methods of geostatistics and geographic information system (GIS), the correlation between environmental pollution and chronic non-communicable diseases such as cancers, cardiovascular and cerebrovascular diseases was systematically studied.
Zhang X, Tang M, Guo F, Wei F, Yu Z, Gao K, Jin M, Wang J, Chen K*. Associations between air pollution and COVID-19 epidemic during quarantine period in China. Environ Pollut. 2021 Jan 1;268(Pt A):115897.
Wu M, Lu J, Yang Z, Wei F, Shen P, Yu Z, Tang M, Jin M, Lin H, Chen K*, Wang J*. Ambient air pollution and hospital visits for peptic ulcer disease in China: A three-year analysis. Environ Res. 2020 Oct 29:110347. Epub ahead of print.
Yu Z, Mao X, Tang M, Chen Y, Wu M, Jin M, Wang J, Xu L, Ye G, Ding J, Ye B, Chen D, Chen Y, Chen X, Sheng X, Li H, Chen Q, Teng X, Ding Q, Yang H, Shen Z*, Chen K*, Yu C*. Association between past exposure to fine particulate matter (PM2.5) and peptic ulcer: A cross-sectional study in eastern China. Chemosphere. 2020 Oct 29:128706.
Wu M, Wang J*, Zhu Y, Lu J, Li D, Yu Z, Shen P, Jiang D, Lin H, Chen K*. Impact of individual and combined lifestyle factors on mortality in china: a cohort study. Am J Prev Med. 2020 Sep;59(3):461-468.
Lin C, Li D, Lu J, Yu Z, Zhu Y, Shen P, Tang M, Jin M, Lin H, Shui L, Chen K*, Wang J*. Short-term associations between ambient fine particulate matter pollution and hospital visits for chronic obstructive pulmonary disease in Yinzhou District, China. Environ Sci Pollut Res Int. 2020 Jun;27(17):21647-21653.
Yu Z, Bao C, Wu M, Jiang D, Zhang X, Lin S, Jin M, Wang J, Tang M, Chen K*. Regression-based normative data for social health scale for the elderly (short version) in eastern China. Health Qual Life Outcomes. 2020 Mar 4;18(1):54.
Lu J, Yu Z, Zhang X, Wu M, Lin S, Zhu Y, Xu Z, You L, Wei F, Tang M, Jin M, Wang J*, Chen K*. Association between social health status and health-related quality of life among community-dwelling elderly in Zhejiang. Health Qual Life Outcomes. 2020 Apr 28;18(1):110.
Wei F, Wu M, Qian S, Li D, Jin M, Wang J, Shui L, Lin H, Tang M*, Chen K*. Association between short-term exposure to ambient air pollution and hospital visits for depression in China. Sci Total Environ. 2020 Jul 1;724:138207.
Zhang H*, Guo F, Tang M, Dai H, Sheng J, Chen L, Liu S, Wang J, Shi Y, Ye C, Hou G, Wu X, Jin X, Chen K*. Association between Skeletal Muscle Strength and Dysphagia among Chinese Community-Dwelling Elderly Adults. J Nutr Health Aging. 2020;24(6):642-649.
Wang P, Chen K*, Gut microbiota and hepatocellular carcinoma. Hepatobiliary surgery and nutrition. 2020; 9(3): p. 345-347.
Ye D, Jiang D, Gu S, Mao Y, Qian S, Lin S, Li Q, Yang J, Zhong K, Jin M*, Chen K*. Evaluating the predictive value of genetic risk score in colorectal cancer among Chinese Han population. Journal of Human Genetics volume. 2020; 65(3):271-279.
Yu Z, Zhu Y, Li D, Wu M, Tang M, Wang J*, Chen K*. Association between visit-to-visit variability of HbA1c and cognitive decline: a pooled analysis of two prospective population-based cohorts. Diabetologia. 2020;63(1):85-94.
Li D, Wang J*, Yu Z, Lin H, Chen K*. Air pollutants concentration and variation of blood glucose level among pregnant women in China: A cross-sectional study, Atmospheric Environment. 2020;223: 1-8.
Tang M, Li D, Liew Z, Wei F, Wang J, Jin M, Chen K*, Ritz B. The association of short-term effects of air pollution and sleep disorders among elderly residents in China. Sci Total Environ. 2020;708: 1-7.
Jiang D, Jin M, Ye D, Li Y, Jing F, Zhang X, Li Q, Chen K*. Polymorphisms of a novel long non-coding RNA RP11-108K3.2 with colorectal cancer susceptibility and their effects on its expression. The International Journal of Biological Markers. 2019:1-7.
You L, Yu Z, Zhang X, Wu M, Lin S, Zhu Y, Xu Z, Lu J, Wei F, Tang M, Wang J, Jin M*, Chen K*. Association between multimorbidity and depressive symptom among community-dwelling elders in eastern china. Clinical Interventions in Aging. 2019;14: 2273-2280.
Zhu Y, Lu J, Yu Z, Li D, Wu M, Shen P, Lin H, Wang J*, Chen K*. Intra-individual variability of total cholesterol is associated with cardiovascular disease mortality: A cohort study. Nutr Metab Cardiovasc Dis. 2019;29(11):1205-1213.
Zhu Y, Hu S, Zheng P, Jin M, Tang M, Chen K*, Wang J*. Association between CPR-related genetic variants and risk of ischemic stroke: a nested case-control study. Neurol Res. 2019;41(12):1090-1096.
Gu S, Lin S, Ye D, Qian S, Jiang D, Zhang X, Li Q, Yang J, Ying X, Li Z, Tang M, Wang J, Jin M*, Chen K*. Genome-wide methylation profiling identified novel differentially hypermethylated biomarker MPPED2 in colorectal cancer. Clin Epigenetics. 2019;11(41):1-12.
Jiang D, Chen K*. Assessing the postoperative behaviors of minimally-invasive pancreatoduodenectomy versus open pancreatoduodenectomy. Hepatobiliary surgery and nutrition. 2019;8(3):314-5.
Yu Z, Li D, Chen X, Zheng P, Lin H, Tang M, Jin M, Wang J*, Chen K*. Association of visit-to-visit variability of blood pressure with cardiovascular disease among type 2 diabetes mellitus patients: a cohort study. Diabetes & metabolism journal. 2019;43(3):350-67.
Li D, Wang J*, Yu Z, Lin H, Chen K*. Air pollution exposures and blood pressure variation in type-2 diabetes mellitus patients: A retrospective cohort study in China. Ecotoxicol Environ Saf. 2019;171:206-10.
Zhang Z, Chai P, Wang J, Ye Z, Shen P, Lu H, Jin M, Gu M, Li D, Lin H*, Chen K*. Association of particulate matter air pollution and hospital visits for respiratory diseases: a time-series study from China. Environmental Science and Pollution Research. 2019;26(12):12280-12287.
Yu Z, Wang J, Li D, Chen X, Lin H, Chen K*. Prognostic value of visit-to-visit systolic blood pressure variability related to diabetic kidney disease among patients with type 2 diabetes. Journal of hypertension. 2019;37(7):1411-8.
Zheng P, Shen P, Ye Z, Zhang Z, Chai P, Li D, Jin M, Tang M, Lu H, Lin H, Wang J*, Chen K*. Acute effect of fine and coarse particular matter on cardiovascular visits in Ningbo, China. Environ Sci Pollut Res Int. 2018;25(33):33548-33555.
Zhang Z, Wang J, Hart J, Laden F, Zhao C, Li T, Zheng P, Li D, Ye Z, Chen K*. National scale spatiotemporal land-use regression model for PM2.5, PMio and NO2 concentration in China[J]. ATMOSPHERIC ENVIRONMENT.2018;192:48-54.
Tang M, Yin S, Zhang J, Chen K, Jin M, Liu W*. Prenatal exposure to polychlorinated biphenyl and umbilical cord hormones and birth outcomes in an island population. Environmental Pollution. 2018;237: 581-591.
Gu M, Huang Q, Bao C, Li Y, Li X, Ye D, Ye Z, Chen K*, Wang J*. Attributable causes of colorectal cancer in China. BMC Cancer. 2018;18(38):1-9.
Bao C, Yu Z, Yin X, Chen Z, Meng L, Yang W, Chen X, Jin M, Wang J, Tang M, Chen K*. The development of the social health scale for the elderly. Health Qual Life Out, 2018;16(67):1-14.
Li D, Wang J*, Zhang Z, Shen P, Zheng P, Jin M, Lu H, Lin H*,Chen K*. Association between short-term exposure to ambient air pollution and daily mortality: a time-series study in Eastern China. Environmental Science and Pollution Research. 2018;25(16):16135-16143.
Li D, Wang J*, Zhang Z, Shen P, Zheng P, Jin M, Lu H, Lin H*, Chen K*. Effects of air pollution on hospital visits for pneumonia in children: a two-year analysis from China. Environ Sci Pollut Res Int. 2018;25(10):10049-10057.
Liu W, Yu Z, Qiu H, Wang J, Chen X, Chen K*. Association between ambient air pollutants and preterm birth in Ningbo, China: a time-series study. BMC Pediatr. 2018;18(1):305.
Jiang X, Cai S, Hu Y, Ye D, Li Q, Chen K, Jin M*. Sex disparities in cancer incidence in Jiashan County, China, 1995-2014. Cancer Epidemiol. 2017;50(Pt A):46-52.
Ye D, Huang Q, Li Q, Jiang X, Mamat M, Tang M, Wang J, Chen K*. Comparative evaluation of preliminary screening methods for colorectal cancer in a mass program. Dig Dis Sci. 2017;62(9):2532-2541.
Jin M, Gu S, Ye D, Li Y, Jing F, Li Q, Chen K*. Association between genetic variants in the promoter region of a novel antisense long noncoding RNA RP11-392P7.6 and colorectal cancer risk. Environ Mol Mutagen. 2017;58(6):434-442.
Ye D, Jiang D, Li Y, Jin M, Chen K*. The role of LINE-1 methylation in predicting survival among colorectal cancer patients: a meta-analysis. Int J Clin Oncol. 2017;22(4):749-757.
Jing F, Jin H, Mao Y, Li Y, Ding Y, Fan C, Chen K*. Genome-wide analysis of long non-coding RNA expression and function in colorectal cancer. Tumour Biol. 2017;39(5):1010428317703650.
Jin M, Ye D, Li Y, Jing F, Jiang X, Gu S, Mao Y, Li Q, Chen K*. Association of a novel genetic variant in RP11-650L12.2 with risk of colorectal cancer in Han Chinese population. Gene. 2017;624:21-25.
Ye D, Hu Y, Jing F, Li Y, Gu S, Jiang X, Mao Y, Li Q, Jin M*, Chen K*. A novel SNP in promoter region of RP11-3N2.1 is associated with reduced risk of colorectal cancer. J Hum Genet. 2018;63(1):47-54.
Li Y, Bao C, Gu S, Ye D, Jing F, Fan C, Jin M, Chen K*. Associations between novel genetic variants in the promoter region of MALAT1 and risk of colorectal cancer. Oncotarget. 2017;8(54):92604-92614.
Zheng P, Wang J, Zhang Z, Shen P, Chai P, Li D, Jin M, Tang M, Lu H, Lin H*, Chen K*. Air pollution and hospital visits for acute upper and lower respiratory infections among children in Ningbo, China: A time-series analysis. Environmental Science and Pollution Research. 2017; 24(23):1-10.
Xu X, Chang W, Yuan J, Han X, Tan X, Ding Y, Luo Y, Cai H, Liu Y, Gao X, Liu Q, Yu Y, Du Y, Wang H, Ma L, Wang J, Chen K, Ding Y, Fu C*, Cao G*. Periostin expression in intra-tumoral stromal cells is prognostic and predictive for colorectal carcinoma via creating a cancer-supportive niche. Oncotarget. 2016; 7(1):798-813.
Qian Y, Li P, Zhang J, Shi Y, Chen K, Yang J, Wu Y*, Ye X*. Association between peroxisome proliferator-activated receptor-alpha, delta, and gamma polymorphisms and risk of coronary heart disease A case-control study and meta-analysis. Medicine. 2016; 95(32):e4299.
Ye D, Cai S, Jiang X, Ding Y, Chen K, Fan C, Jin M*. Associations of polymorphisms in circadian genes with abdominal obesity in Chinese adult population. Obesity Research & Clinical Practice. 2016; 101:S133-S141.
Bao C, Chai P, Lin H, Zhang Z, Ye Z, Gu M, Lu H, Shen P, Jin M, Wang J, Chen K*. Association of PM2.5 pollution with the pattern of human activity: a case study of a developed city in Eastern China. Journal of the Air & Waste Management Association. 2016; 66(12):1202-1213.
Wang J, Gu M, Shen P, Huang Q, Bao C, Ye Z, Wang Y, Mayila M, Ye D, Gu S, Lin H*, Chen K*. Body mass index and mortality: a 10-year prospective study in china. Scientific Reports. 2016; 6:31609.
Li Y, Gu M, Jing F, Cai S, Bao C, Wang J, Jin M, Chen K*. Association between physical activity and all cancer mortality: Dose-response meta-analysis of cohort studies. International Journal of Cancer. 2016; 138(4):818-832.
Study on the association between CpG-SNPs and development of colorectal cancer and its mechanism. Funding Source: National Natural Science Foundation of China.
Molecular epidemiology of long non-coding RNA methylation, colorectal adenoma and colorectal cancer development. Funding Source: National Natural Science Foundation of China.
Parameters of social health assessment tools for the elderly. Funding Source: Science and Technology Basic Work of Ministry of Science and Technology of China.