Cai Jianting, M.D., Ph.D.

Position:Chair of Gastroenterology

Department:Gastroenterology

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Chief Physician, Professor


Appointment

Clinical / Research Interests

Gastrointestinal endoscopic diagnosis and treatment, especially ERCP and ESD

Clinical and molecular research of pancreaticobiliary disease, especially endoscopic therapy and medical management of ccute/chronic pancreatitis and pancreatic cancer

Pathogenesis of gastrointestinal malignancy

Epidemiology of gastrointestinal diseases

Professional Highlights

Professional Appointments

Member, Editorial Board, Chinese Journal of Digestion

Member, Editorial Board, Chinese Journal of Pancreatology

Education Experience

Research Summary

Publications

Dan L, Qin P, Xie S, Sun Y, Fu T, Ruan X, Shi W, Chen J, Cai J, Li X. Risk of subsequent gastrointestinal disease assessed by skeletal muscle strength and mass in a prospective cohort study. iScience. 2024 Mar 5;27(4):109341. doi: 10.1016/j.isci.2024.109341.

Cai Y, Xie S, Jia X, Chen D, Wu D, Bao W, Cai J, Mao J, Ye J. Integrated analysis of Mendelian Randomization and Bayesian colocalization reveals bidirectional causal association between inflammatory bowel disease and psoriasis. Ann Med. 2023;55(2):2281658. doi: 10.1080/07853890.2023.2281658.

Cai Y, Jia X, Xu L, Chen H, Xie S, Cai J. Interleukin-17 and inflammatory bowel disease: a 2-sample Mendelian randomization study. Front Immunol. 2023 Nov 17;14:1238457. doi: 10.3389/fimmu.2023.1238457.

Chen H, Li P, Chen J, Wang Y, Yu Q, Wu Y, Chen Y, Cai J. Peripheral blood mononuclear cell microRNAs are novel biomarkers for diagnosing and monitoring Crohn's disease. FASEB J. 2022 Oct;36(10):e22549. doi: 10.1096/fj.202200452R.

Xu L, Cai Y, Chen X, Zhu Y, Cai J. Circulating MiR-1290 as a potential diagnostic and disease monitoring biomarker of human gastrointestinal tumors. BMC Cancer. 2021 Sep 3;21(1):989. doi: 10.1186/s12885-021-08729-0.

Wu J, Cai J. Dilemma and Challenge of Immunotherapy for Pancreatic Cancer. Dig Dis Sci. 2021 Feb;66(2):359-368. doi: 10.1007/s10620-020-06183-9.

Xu L, Chen J, Jia L, Chen X, Awaleh Moumin F, Cai J. SLC1A3 promotes gastric cancer progression via the PI3K/AKT signalling pathway. J Cell Mol Med. 2020 Dec;24(24):14392-14404. doi: 10.1111/jcmm.16060.

Shao L, Li P, Ye J, Chen J, Han Y, Cai J, Lu X. Risk of gastric cancer among patients with gastric intestinal metaplasia. Int J Cancer. 2018 Oct 1;143(7):1671-1677. doi: 10.1002/ijc.31571.

Ma W, Yang J, Li P, Lu X, Cai J. Association between allergic conditions and colorectal cancer risk/mortality: a meta-analysis of prospective studies. Sci Rep. 2017 Jul 17;7(1):5589. doi: 10.1038/s41598-017-04772-9.

Li P, Wu H, Zhang H, Shi Y, Xu J, Ye Y, Xia D, Yang J, Cai J, Wu Y. Aspirin use after diagnosis but not prediagnosis improves established colorectal cancer survival: a meta-analysis. Gut. 2015 Sep;64(9):1419-25. doi: 10.1136/gutjnl-2014-308260.

Li P, Zhang H, Chen J, Shi Y, Cai J, Yang J, Wu Y. Association between dietary antioxidant vitamins intake/blood level and risk of gastric cancer. Int J Cancer. 2014 Sep 15;135(6):1444-53. doi: 10.1002/ijc.28777.

Wu J, Ji X, Zhu L, Jiang Q, Wen Z, Xu S, Shao W, Cai J, Du Q, Zhu Y, Mao J. Up-regulation of microRNA-1290 impairs cytokinesis and affects the reprogramming of colon cancer cells. Cancer Lett. 2013 Feb 28;329(2):155-63. doi: 10.1016/j.canlet.2012.10.038.

Current Program

Identification of key mitochondrial proteins and molecular mechanisms involved in the CD8+ T cell exhaustion induced by tumor microenvironment of colorectal cancer, National Natural Science Foundation of China (No. 82073160).

Research and development of key technologies and related products for early screening of pancreatic cancer. Key Research and Development Program of Zhejiang Province (2014C03041-1).

A multicenter, single-arm, prospective, non-interventional study using Vonorosine in real-world clinical practice in China (391020-I42201).

A randomized, double-blind, placebo-controlled, parallel-controlled, multi-center clinical study of Dexitacin in patients with functional dyspepsia (491020-I4230A).

The development of artificial intelligence graphic workstation(491020-I22005)

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