Publications

Ullah S#, Ji K#, Li J, Xu Y, Jiang C, Zhang H, Huang M, Feng Y*, Characterization of NMCR-2, a new non-mobile colistin resistance enzyme: Implications for an MCR-8 ancestor. Environ Microbiol, 2020, July 20. doi: 10.1111/1462-2920.15171. 

Zhang H, Srinivas S, Xu Y, Wei W, Feng Y*, Genetic and biochemical mechanisms for bacterial lipid A modifiers associated with polymyxin resistance. Trends Biochem Sci, 2019 Nov; 44(11):973-988. 

Gao R, Wei W, Hassan BH, Li J, Deng J, Feng Y*, A single regulator NrtR maintains bacterial NAD+ homeostasis via its acetylation. eLife, 2019 Oct 9; 8: e51603. 

Wei W#, Guan H#, Zhu T#, Zhang S#, Fan C, Ouyang S*, Feng Y*, Molecular basis of BioJ, a unique gatekeeper in bacterial biotin synthesis. iScience, 2019 Aug 22; 19: 796-808.

Xu Y, Liu L, Sun J, Feng Y*, Limited distribution and mechanism for the TetX4 tigecycline resistance enzyme. Sci Bull, 2019, 64(20): 1478-1481. 

Zhang H#, Wei W#, Huang M, Umar Z, Feng Y*, Definition of a family of nonmobile colistin resistance (NMCR-1) determinants suggests aquatic reservoirs for MCR-4. Adv Sci, 2019, 6(11): 201900038. 

Zhang H#, Zong Z#*, Lei S#, Srinivas S, Sun J, Feng Y, Huang M, Feng Y*, A genomic, evolutionary, and mechanistic study of MCR-5 action suggests functional unification across the MCR family of colistin resistance. Adv Sci, 2019, 6(11): 201900034. 

Wang Q, Hassan BH, Lou N, Merritt J, Feng Y*, Functional definition of NrtR, a remnant regulator of NAD+ homeostasis in the zoonotic pathogen, Streptococcus suis. FASEB J. 2019 May; 33(5): 6055-6068. 

Zhang H#, Hou M#, Xu Y#, Srinivas S, Huang M, Liu L, Feng Y*, Action and mechanism of the colistin resistance enzyme MCR-4. Commun Biol. 2019 Jan 25; 2: 36. 

Xu Y#, Zhong L#, Srinivas S#, Sun J#, Paterson DL, Lei S, Lin J, Xin Li, Tang Z, Feng S, Shen C, Tian GB*, Feng Y*, Spread of MCR-3 colistin resistance in China: An epidemiological, genomic and mechanistic study. EBioMedicine, 2018, 34: 139-157. 

Wei W#, Zhang Y#, Gao R#, Li J, Xu Y, Wang S, Ji Q*, Feng Y*, Crystal structure and acetylation of BioQ suggests a novel regulatory switch for biotin biosynthesis in Mycobacterium smegmatis. Mol Microbiol, 2018 Sep; 109(5): 642-662.

Wei W#, Srinivas S#, Lin J#, Tang Z#, Wang SH, Ullah S, Kota VG, Feng Y*, Defining ICR-Mo, an intrinsic colistin resistance determinant from Moraxella osloensis. PLoS Genet, 2018, May 14;14(5): e1007389. 

Xu Y#, Wei W#, Lei S#, Lin J, Srinivas S, Feng Y*, An evolutionarily-conserved mechanism for intrinsic and transferable polymyxin resistance. mBio, 2018 Apr 10; 9 (2): e02317-17. 

Sun J#, Zhang H#, Liu YH*, Feng Y*, Towards understanding MCR-like colistin resistance. Trends Microbiol, 2018 Sep; 26(9): 794-808.

Xu Y#, Lin J#, Cui T#, Srinivas S, Feng Y*, Mechanistic insights into transferable polymyxin resistance among gut bacteria. J Biol Chem, 2018 Mar 23; 293 (12): 4350-4365.

Wang Q#, Sun J#, Li J#, Ding Y, Li XP, Lin J, Hassan B, Feng Y*. Expanding landscapes of the diversified mcr-1-bearing plasmid reservoirs. Microbiome. 2017, Jul 6; 5(1):70. 

Sun J#, Xu Y#, Gao R#, Lin J, Wei W, Srinivas S, Li D, Yang RS, Li XP, Liao XP, Liu YH*, Feng Y*. Deciphering MCR-2 colistin resistance. mBio. 2017 May 9; 8(3): e00625-17.

Wang Q, Sun J, Ding Y, Li XP, Liu YH, Feng Y*. Genomic insights into mcr-1-positive plasmids carried by the colistin-resistant Escherichia coli from the inpatients. AAC. 2017 Jun 27; 61(7): e00361-17. 

Gao R#, Hu Y#, Li Z#, Sun J#, Wang Q, Lin J, Ye H, Liu F, Srinivas S, Li D, Zhu B, Liu Y, Tian GB, Feng Y*. Dissemination and mechanism for the MCR-1 colistin resistance. PLoS Pathog, 2016, 12 (11): e1005957.

Shi X#, Ye H#, Wang J, Li Z, Wang J, Chen B, Wen R, Hu Q, Feng Y*, Loss of 89K pathogenicity island in epidemic Streptococcus suis, China. Emerg Infect Dis 2016 Jun; 22(6):1126-1127.

Ye H#, Li Y#, Li Z, Gao R, Zhang H, Wen R, Gao GF, Hu Q, Feng Y*, Diversified mcr-1-harbouring plasmid reservoirs confer resistance to colistin in human gut microbiota. mBio, 2016 Apr 5; 7(2): e00177-16.  

Zhang H, Seward C, Wu Z, Ye H, Feng Y*, Genomic insights into the ESBL and MCR-1-producing ST648 Escherichia coli with multi-drug resistance. Sci Bull 2016, 61: 875-878.

Gao R#, Lin J#, Zhang H, Feng Y*, Transcriptional repression of the VC2105 by the Vibrio FadR suggests a new auxilliary member of fad regulon. Appl Environ Microbiol. 2016 Mar 4. 82(9): 2819-2832. 

Zhang H, Zheng B, Gao R, Feng Y*, Binding of Shewanella FadR to the fabA fatty acid biosynthetic gene: Implications for contraction of the fad regulon. Protein & Cell, 2015, 6(9): 667-679.

Tang Q, Li X, Zou T, Zhang H, Wang Y, Gao R, Li Z, He J*, Feng Y*. Mycobacterium smegmatis BioQ defines a new regulatory network for biotin metabolism. Mol Microbiol, 2014, 94(5): 1006-1020. 

Zhang Y, Gao R, Ye H, Wang Q, Feng Y*, A new glimpse of FadR-DNA crosstalk revealed by deep dissection of the E. coli FadR regulatory protein. Protein & Cell, 2014, 5(12): 928-39.