Hong Yi, Ph.D.

Department:Orthopedics

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Professor



Clinical / Research Interests

Bone / cartilage repair hydrogel

Fast light response bio-gel

Fast light projection 3D printing bio-ink and printing technology


Professional Highlights

Outstanding Paper Award, The Fourteenth National Conference on Biomaterials

Outstanding Youth Papers in "The Ninth National Conference on Tissue Engineering and Regenerative Medicine", First Prize


Professional Appointments

Youth Member, Chinese Tissue Engineering Society, 2018-present 

Education Experience

Research Summary

By chemically modifying natural biological macromolecules, Dr. Hong has obtained intelligent bionic hydrogel materials that have multiple functions such as rapid controllable gelling and strong wet surface tissue adhesion, which are used for tissue regeneration and 3D bio-printing. 

Among them, by using fast photo-curable tissue adhesive hydrogels, Dr. Hong achieved rapid hemostasis against cardiac penetrating bleeding in large animal models without sutures for the first time; By using photosensitive hydrogel with high strength, we achieved "seamless" perfect repair of bone / cartilage defects; By using photosensitive biomimetic inks, Dr. Hong printed stem cell expansion microcarriers and bionic organs. Related studies have been published in journals such as Nature Communications, Biomaterials, Small and Applied Materials Today, and have received attention and reports from well-known media at home and abroad.

Publications

Hong, Yi#; Yu, Mengfei#; Weng, Wenjian; Cheng, Kui*; Wang, Huiming; Lin, Jun; Light-induced cell detachment for cell sheet technology, Biomaterials, 2013, 34(1): 11-18.

Hong, Yi#; Yu, Mengfei#; Lin, Jun; Cheng, Kui*; Weng, Wenjian*; Wang, Huiming*; Surface hydroxyl groups direct cellular response on amorphous and anatase TiO2 nanodots, COLLOIDS AND SURFACES B-BIOINTERFACES, 2014, 123: 68-74.

Feifei Zhou#; Yi Hong#; Xianzhu Zhang; Long Yang; Jun Li; Deming Jiang; Varitsara Bunpetch; Yejun Hu; Hongwei Ouyang; Shufang Zhang;Tough hydrogel with enhanced tissue integration and in situ forming capability for osteochondral defect repair, Applied Materials Today, 2018, 13: 32-44. 

Hong, Yi#; Zhou, Feifei#; Hua, Yujie; Zhang, Xianzhu; Ni, Chengyao; Pan, Dihao; Zhang, Yiqing; Jiang, Deming; Yang, Long; Lin, Qiuning; Zou, Yiwei; Yu, Dongsheng; Arnot, David E; Zou, Xiaohui; Zhu, Linyong*; Zhang, Shufang*; Ouyang, Hongwei*; A strongly adhesive hemostatic hydrogel for the repair of arterial and heart bleeds, Nature Communications, 2019, 10(1): 0-2060. 

Qiulin He#; Youguo Liao#; Jingwei Zhang; Xudong Yao; Wenyan Zhou; Yi Hong*; Hongwei Ouyang*; “All‐in‐One” Gel System for Whole Procedure of Stem‐Cell Amplification and Tissue Engineering, Small, 2020, 1906539. 

Feifei Zhou#, Yi Hong#, Renjie Liang, Xianzhu Zhang, Youguo Liao, Deming Jiang, Jiayan Zhang, Zixuan Sheng, Chang Xie, Zhi Peng, Xinhao Zhuang, Varitsara Bunpetch, Yiwei Zou, Wenwen Huang, Qin Zhang, Enateri Vera Alakpa, Shufang Zhang*, Hongwei Ouyang*. Rapid printing of bio-inspired 3D tissue constructs for skin regeneration. Biomaterials, 2020, 120287.

Current Program

Research on printing bionic meniscus with high resilience and compressive bio-ink. Funding Source: National Natural Science Youth Science Foundation of China.

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