Jin Mingjuan, M.D., Ph.D.

Department:Cancer Institute

Medical School:Zhejiang University School of Public Administration, China

Academic Rank:Associate Chief Professor



Clinical / Research Interests

Clinical epidemiology

Evidence-based medicine

Colorectal cancer epidemiology and screening

Cervical cancer epidemiology and screening


Professional Highlights

Professional Appointments

Youth Committee Member, Clinical Epidemiology and Evidence-Based Medicine Branch, Chinese Medical Association, 2016-2019

Youth Committee Member, Epidemiology Branch, Chinese Preventive Medicine Association, 2019-present

Committee Member, Cancer Epidemiology Committee, China Anti-Cancer Association, 2019-present

Committee Member, Cancer Screening and Early Diagnosis and Treatment Committee, China Anti-Cancer Association, 2019-present


Education Experience

Research Summary

Dr. Jin has been carried a series of studies on genetic susceptibility, epigenetic changes, and their interactions with environmental exposures in colorectal cancer and its precancerous lesions, using molecular epidemiological approaches, with the combination of population-based and hospital-based case-control studies, to clarify their etiology, identify proper biomarkers, and develop efficient risk assessment model. 

Dr. Jin also has been studied the risk prediction of hepatocellular carcinoma developing from chronic HCV and HBV patients with cohort study design and the current challenges of hepatocellular carcinoma screening among high-risk population.

Dr. Jin also has been leading a series of studies on the relationships of alcohol drinking with cancer deaths with evidence-based assessments and systematic reviews. 

And now, she mainly focuses on the etiology, epidemiology, prevention and control of colorectal cancer and cervical cancer.


Publications

Ding Ye, Danjie Jiang, Simeng Gu, Yingying Mao, Sangni Qian, Shujuan Lin, Qilong Li, Jinhua Yang, Kunhong Zhong, Mingjuan Jin & Kun Chen. Evaluating the predictive value of genetic risk score in colorectal cancer among Chinese Han population. Journal of Human Genetics, 2020; 65(3): 271-9.

Danjie Jiang#, Mingjuan Jin#, Ding Ye, et al. Polymorphisms of a novel long non-coding RNA RP11-108K3.2 with colorectal cancer susceptibility and their effects on its expression. International Journal of Biological Markers, 2020; 35(1): 3-9.

Simeng Gu, Shujuan Lin, Ding Ye, Sangni Qian, Danjie Jiang, Xiaocong Zhang, Qilong Li, Jinhua Yang, Xiaojiang Ying, Zhenjun Li, Mengling Tang, Jianbing Wang, Mingjuan Jin and Kun Chen. Genome-wide methylation profiling identified novel differentially hypermethylated biomarker MPPED2 in colorectal cancer. Clin Epigenetics, 2019; 11: 41.

Liuqing You, Zhebin Yu, Xiaocong Zhang, Mengyin Wu, Shujuan Lin, Yao Zhu, Zenghao Xu, Jieming Lu, Fang Wei, Mengling Tang, Jianbing Wang, Mingjuan Jin, Kun Chen. Association between multimorbidity and depressive symptom among community-dwelling elders in eastern China. Clin Interv Aging, 2019; 14: 2273-80.

Changqing Zhao#, Mingjuan Jin#, Richard Hieu Le, et al. Poor adherence to hepatocellular carcinoma surveillance: A systematic review and meta-analysis of a complex issue. Liver International, 2018, 38(3): 503-14.

Ding Ye, Yunqing Hu, Fangyuan Jing, Yingjun Li, Simeng Gu, Xiyi Jiang, Yingying Mao, Qilong Li, Mingjuan Jin & Kun Chen. A novel SNP in promoter region of RP11-3N2.1 is associated with reduced risk of colorectal cancer. Journal of Human Genetics, 2018; 63(1): 47-54.

Mingjuan Jin, Simeng Gu, Ding Ye, et al. Association between genetic variants in the promoter region of a novel antisense long noncoding RNA RP11-392P7.6 and colorectal cancer risk. Environmental and Molecular Mutagenesis, 2017, 58(6): 434-42.

Mingjuan Jin#, Ding Ye#, Yingjun Li, et al. Association of a novel genetic variant in RP11-650L12.2 with risk of colorectal cancer in Han Chinese population. Gene, 2017, 624: 21-5.

Ding Ye, Shaofang Cai, Xiyi Jiang, Ye Ding, Kun Chen, Chunhong Fan, Mingjuan Jin. Associations of polymorphisms in circadian genes with abdominal obesity in Chinese adult population. Obesity Research & Clinical Practice, 2016; 10(Suppl 1): S133-41.

YJ Li, YY Mao, Y Zhang, SF Cai, GD Chen, Y Ding, J Guo, K Chen, MJ Jin. Alcohol drinking and upper aerodigestive tract cancer mortality: A systematic review and meta-analysis. Oral Oncology, 2014, 50(4): 269-75.

Shaofang Cai, Yingjun Li, Ding, Kun Chen, Mingjuan Jin. Alcohol drinking and the risk of colorectal cancer death: a meta-analysis. European Journal of Cancer Prevention, 2014, 23(6): 532-9.

Mingjuan Jin, Shaofang Cai, Jing Guo, et al. Alcohol drinking and all cancer mortality: a meta-analysis. Annals of Oncology, 2013, 24(3): 807-16.

Mingjuan Jin, Bingbing Chen, Yingying Mao, et al. Prevalence of overweight and obesity and their associations with socioeconomic status in a rural Han Chinese adult population. PLoS One, 2013, 8(11): e79946.

Mei-Hsuan Lee, Tiffany I Hsiao, Shreenidhi R Subramaniam, An K Le, Vinh D Vu, Huy N Trinh, Jian Zhang, Mingjuan Jin, Vincent Wai-Sun Wong, Grace Lai-Hung Wong, Mindie H Nguyen. HCV Genotype 6 increased the risk for hepatocellular carcinoma among Asian patients with liver cirrhosis. American Journal of Gastroenterology, 2017;112(7): 1111-9.

A K Le, C Zhao, J K Hoang, S A Tran, C Y Chang, M Jin, N H Nguyen, L A Yasukawa, J Q Zhang, S C Weber, G Garcia, M H Nguyen. Ethnic disparities in progression to advanced liver disease and overall survival in patients with chronic hepatitis C: impact of a sustained virological response. Alimentary Pharmacology & Therapeutics, 2017; 46(6): 605-16.

Brittany E. Yee, Nghia H. Nguyen, Minjuan Jin, et al. Lower response to simeprevir and sofosbuvir in HCV genotype 1 in routine practice compared with clinical trials. BMJ Open Gastroenterology, 2016; 3(1): e000056.

Nghia H Nguyen, Brittany E Yee, Christine Chang, Minjuan Jin, Glen Lutchman, Joseph K Lim, Mindie H Nguyen. Tolerability and effectiveness of sofosbuvir and simeprevir in the post-transplant setting: systematic review and meta-analysis. BMJ Open Gastroenterology, 2016; 3(1): e000066.

Current Program

The contribution and corresponding mechanism of tRNA-derived small RNA to colorectal cancer development. Funding Source: National Natural Science Foundation of China.

The validation of novel techniques of cancer surveillance and control in large cohort.  Funding Source: Ministry of Science and Technology of China.

Prospective molecular epidemiological study on colorectal cancre development and progression. Funding Source: Ministry of Science and Technology of China.


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