Guo Songxue, M.D.

DepartmentPlastic Surgery

Medical SchoolZhejiang University School of Medicine, China

Academic RankAssociate Chief Physician


Clinical / Research Interests

Superficial organ reconstruction, wound healing, composite tissue allotransplantation, burn-wound progression, mitophagy

Professional Highlights

Zhejiang Scientific and Technological Progress Award, Second Prize

Professional Appointments

Education Experience

Research Summary


Guo S, Yu M, Fang Q, Zhang L, You C, Wang X, Liu Y, Han C. Heme oxygenase-1 induction mitigates burn-associated early acute kidney injury via the TLR4 signaling pathway. Burns. 2022 Feb;48(1):156-167.   doi:10.1016/j.burns.2021.04.013.

Guo S, Fang Q, Chen L, Yu M, Chen Y, Li N, Han C, Hu X. Locally activated mitophagy contributes to a "built-in" protection against early burn-wound progression in rats. Life Sci. 2021 Jul 1;276:119095. doi: 10.1016/j.lfs.2021.119095.

Zhou H, Fang Q, Li N, Yu M, Chen H, Guo S. ASMq protects against early burn wound progression in rats by alleviating oxidative stress and secondary mitochondria-associated apoptosis via the Erk/p90RSK/Bad pathway. Mol Med Rep. 2021 May;23(5):390. doi: 10.3892/mmr.2021.12029.

Guo S, Guo L, Fang Q, Yu M, Zhang L, You C, Wang X, Liu Y, Han C. Astaxanthin protects against early acute kidney injury in severely burned rats by inactivating the TLR4/MyD88/NF-κB axis and upregulating heme oxygenase-1. Sci Rep. 2021 Mar 23;11(1):6679. doi: 10.1038/s41598-021-86146-w.

Chen Y, Guo S, Tang Y, Mou C, Hu X, Shao F, Yan W, Wu Q. Mitochondrial Fusion and Fission in Neuronal Death Induced by Cerebral Ischemia-Reperfusion and Its Clinical Application: A Mini-Review. Med Sci Monit. 2020 Nov 6;26:e928651. doi: 10.12659/MSM.928651.

Chen T, Guo S, Zhong P. Epidemic characteristics of the COVID-19 outbreak in Tianjin, a well-developed city in China. Am J Infect Control. 2020 Sep;48(9):1068-1073. doi: 10.1016/j.ajic.2020.06.006.

Zhong P, Guo S, Chen T. Correlation between travellers departing from Wuhan before the Spring Festival and subsequent spread of COVID-19 to all provinces in China. J Travel Med. 2020 May 18;27(3):taaa036. doi: 10.1093/jtm/taaa036.

Weng T, Wu P, Zhang W, Zheng Y, Li Q, Jin R, Chen H, You C, Guo S, Han C, Wang X. Regeneration of skin appendages and nerves: current status and further challenges. J Transl Med. 2020 Feb 3;18(1):53. doi: 10.1186/s12967-020-02248-5.

Liu Y, Wu P, Ho JK, Hua H, Chen H, Cen Y, Guo S, Han C, Wang X. Epidemiology of bus fires in mainland China from 2006 to 2015. Burns. 2018 Jun;44(4):995-999. doi: 10.1016/j.burns.2017.05.024.

Wang Z, Guo S, Wang J, Shen Y, Zhang J, Wu Q. Nrf2/HO-1 mediates the neuroprotective effect of mangiferin on early brain injury after subarachnoid hemorrhage by attenuating mitochondria-related apoptosis and neuroinflammation. Sci Rep. 2017 Sep 19;7(1):11883. doi: 10.1038/s41598-017-12160-6.

Current Program

National Natural Science Foundation of China (Grants No. 81901958)

Zhejiang Provincial Natural Science Foundation of China (Grants No. LY19H150004)

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