Medical School：Zhejiang University School of Medicine, China
Academic Rank：Associate Chief Physician
Organ protection; ischemia-reperfusion injury; inhaled anesthetics.
Sevoflurane mitigates shedding of hyaluronan from the coronary endothelium during ischemia/reperfusion.
Chen C, Chappell D, Annecke T, Conzen P, Jacob M, Welsch U, Zwissler B, Becker BF. Sevoflurane mitigates shedding of hyaluronan from the coronary endothelium, also during ischemia/reperfusion: an ex vivo animal study.Hypoxia (Auckl). 2016; (4): 81-90.
Becker BF*, Fischer J, Hartmann H, Chen CC, Sommerhoff CP, Tschoep J, Conzen PC, Annecke T. Inosine, not adenosine, initiates endothelial glycocalyx degradation in cardiac ischemia and hypoxia. Nucleosides Nucleotides Nucleic Acids. 2011; 30(12):1161-7.
Chappell D*, Heindl B, Jacob M, Annecke T, Chen C, Rehm M, Conzen P, Becker BF. Sevoflurane reduces leukocyte and platelet adhesion after ischemia-reperfusion by protecting the endothelial glycocalyx. Anesthesiology. 2011; 115(3):483-91.
Annecke T*, Chappell D, Chen C, Jacob M, Welsch U, Sommerhoff CP, Rehm M, Conzen PF, Becker BF. Sevoflurane preserves the endothelial glycocalyx against ischaemia-reperfusion injury. Br J Anaesth. 2010; 104(4):414-21.
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