Zhang Hua, M.D., Ph.D.

Department:Orthopedics

Medical School:The Second Military Medical University, China

Academic Rank:Chief Physician


Appointment

Clinical / Research Interests

Cervical spondylosis, lumbar disc herniation, lumbar spinal stenosis, lumbar spondylolisthesis, posterior longitudinal ligament ossification and degenerative scoliosis, and other spinal degenerative diseases, as well as surgical treatment and neurological rehabilitation of cervical and thoracic vertebral fractures and dislocations;

Minimally invasive treatment of lumbar disc herniation with intervertebral foramen, and minimally invasive treatment of thoracolumbar trauma fractures and osteoporotic fractures in the elderly;

Unique experience in diagnosis and treatment of spine fractures and dislocations and deformity corrections.

Professional Highlights

Professional Appointments

Member, Youth Committee, Professional Committee of Spine Surgery, Chinese Research Hospital Association, 2019-present 

Member, Minimally Invasive Group, Professional Committee of Spine Surgery, Chinese Research Hospital Association, 2018-present 

Member, Spinal Rehabilitation Group, Professional Committee of Rehabilitation, China Association for Rehabilitation of the Handicapped, 2016-present

Member and Secretary, Spinal Injury Team, Sports Medicine Branch, Zhejiang Medical Association

Member, Editorial Board, Journal of Spine Surgery

Education Experience

Research Summary

Publications

Hua Zhang; Shan Yu; Xinlian Zhao; Zhengwei Mao ; Changyou Gao, Stromal cell-derived factor-1alpha-encapsulated albumin/heparin nanoparticles for induced stem cell migration and intervertebral disc regeneration in vivo. Acta Biomater, 2018.5.1, 72: 217~227. 

Hua Zhang; Zhu, Ting; Zhang, Li; Wu, Qionghua, Stromal cell‑derived factor‑1 induces matrix metalloproteinase expression in human endplate chondrocytes, cartilage endplate degradation in explant culture, and the amelioration of nucleus pulposus degeneration in vivo. Int J Mol Med, 2018 .2.1, 41(2): 969~976. 

Hua Zhang; Zhang, Li; Li, Zhaodong; Wu, Qionghua; Gao, Jianli, InVitro Immune Activation of Raw264.7 Cells by Nanodiamonds with Different Surface Chemistry. J Nanosci Nanotechnol, 2018.2.1, 18(2): 815~822.        

Hua Zhang; Ajiboye, Remi Musibau; Shamie, Arya Nick; Wu, Qionghua; Chen, Qixin; Chen, Weishan, Morphometric measurement of the lumbosacral spine for minimally invasive cortical bone trajectory implant using computed  tomography. European Spine Journal, 2016.3.01, 25(3): 870~876.  

Zhang, Hua; Fu, Yanbiao; Ye, Zhaoming , Bone multicentric epithelioid hemangioendothelioma of the lower and upper extremities with pulmonary metastases: A case report. Oncology letters, 2015.3.6, 9(5): 2177~2180. 

Zhang, Hua; Zhang, Li ; Chen, Linwei; Li, Wanli; Li, Fangcai; Chen, Qixin, Stromal Cell-derived Factor-1 and its Receptor CXCR4 are Upregulated Expression in Degenerated Intervertebral Discs. International Journal of Medical Sciences, 2014.01.01, 11(3): 240~245. 

Zhang, Hua; Jin, Libin; Li, Wanli; Li, Hang , Anterior dislocation of the sacroiliac joint with complex fractures of the pelvis and femur in children: a case report. Journal of Pediatric Orthopaedics-Part B, 2013.9, 22 (5): 424~426. 

Zhang, Hua; Liang, Zhongyan; Li, Wanli; Li, Fangcai; Chen, Qixin, Nuclear location signal peptide-modified poly (ethyleneimine)/DNA complexes: An efficient gene delivery vector in vitro and in vivo. Journal of Bioactive and Compatible Polymers, 2013.5, 28(3): 218~232.

Zhang, Hua; Li, Wanli; Li, Fangcai; Chen, Qixin; Xu, Kan; Chen, Weishan, A new expanded cage designed for lumbar disc herniation: finite element analysis. SREE Workshop on Medical Materials and Engineering (WMME 2011), 2011.

Zhang, Hua; Ye, Xiao-Jian; Li, Jia-Shun , Preparation and biocompatibility evaluation of apatite/wollastonite-derived porous bioactive glass ceramic scaffolds. Biomedical Materials, 2009.8, 4(4): 045007~045007.

Zhang, Hua, Ye Xiaojian, Xu Guohua, He Hailong, Li Jiashun(*). Biomechanical study on a new expanded cage for lumbar interbody fusion. J Spinal Sugery. 7(4), 216-220, 2009. (Chinese)

Zhang, Hua, Ye Xiaojian, Wang Changfeng, Hu Yuhua, Li Jiashun(*). Influence of unilateral zygapophysial joint resection on intervertebral fusion. J Clinical Rehabilitative Tissue Engineering Research. 13(13), 2470-2474, 2009. (Chinese)

Zhang Hua, Li Jiashun(*),Ye Xiaojian, He Hailong. Recurrent lumbar disc herniation after discectomy alone: long -term results. The Orthopedic J China. 17(3), 183-186, 2009. (Chinese)

Zhang Hua, Ye Xiaojian, Li Jiashun(*). The Relation between the Therapy for Lumbar Spondylosis and the Restitution of Homeostasis. Medicine and Philosophy. 30(1), 66-67, 2009. (Chinese)


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