Department:Nephrology
Medical School:The University of Hong Kong, China
Academic Rank:Associate Chief Physician
Immune-mediated glomerular diseases, including glomerulonephritis, nephrotic syndrome, lupus nephritis and ANCA-associated kidney injury, tubulointerstitial disease, acute/chronic renal failure, peritoneal dialysis, etc.
Youth committee member, International Association of Translational Medicine Specialty Committee of Nephrology
Committee secretary, Zhejiang Preventive Medicine Association, Kidney Disease Prevention and Control Professional Committee
Ph.D., The University of Hong Kong (HKU), 2006-2009
Master, Fudan Univesity, 2002-2005
Bachelor, Jining Medical Colledge/Shandong University,1997-2002
Study the pathogenesis of renal inflammation and fibrosis by focusing on the role of macrophage.
Yang F, Chen J, Huang XR, Yiu WH, Yu X, Tang SCW, Lan HY. Regulatory role and mechanisms of myeloid TLR4 in anti-GBM glomerulonephritis. Cellular and Molecular Life Sciences 2021;78(19-20):6721-6734.
Ni J#, Yang F#, Huang XR, Meng J, Chen J, Bader M, Penninger JM, Fung E, Yu X, Lan HY. Dual deficiency of angiotensin-converting enzyme-2 and Mas receptor enhances angiotensin II-induced hypertension and hypertensive nephropathy. Journal of Cellular and Molecular Medicine. 2020;24(22):13093-13103. (Co-first author)
Yang F, Huang XR, Chung AC, Hou CC, Lai KN, Lan HY. Essential role for Smad3 in angiotensin II-induced tubular epithelial–mesenchymal transition. Journal of Pathology, 2010;221:390-401.
Yang F, Chung ACK, Huang XR, Lan HY. Angiotensin II Induces Connective Tissue Growth Factor and Collagen I Expression via Transforming Growth Factor––Dependent and –Independent Smad Pathways: The Role of Smad3. Hypertension. 2009;54:877-884.
Role and mechanism of myeloid TLR4 in controlling peritoneal macrophage activity related with ongoing dialysate exposure. Funding Source: Zhejiang provincial natural science foundation (NO. Y24H050007), 01/2024-12/2027
Role and mechanism of macrophage in SGLT2 inhibitor to reduce renal fibrosis. Funding Source: Zhejiang Provincial Health Commission (NO. 2021KY702), 01/2021-01-12/2024