Chen Zhida, M.D.

Department:Nephrology

Medical School:Tongji Medical College, Huazhong University of Science and Technology, China

Academic Rank:Associate Chief Physician


Appointment

Clinical / Research Interests

Diabetic kidney disease

Diagnosis and treatment of chronic glomerulonephritis, and renal failure.


Professional Highlights

Professional Appointments

Youth Committee Member, Zhejiang Branch, Chinese Medical Doctor Association of Nephrology

Education Experience

M.D., Tongji Medical College, Huazhong University of Science and Technology

Research Summary

Publications

Chen, Z. #, Wang, Z. #, Hu, Y., Lin, H., Yin, L., Kong, J., Zhang, Y., Hu, B., Li, T., Zheng, X., Yang, Q., Ye, S., Wang, S., Zhou, Q., and Zheng, C. (2023) ELABELA/APJ Axis Prevents Diabetic Glomerular Endothelial Injury by Regulating AMPK/NLRP3 Pathway. Inflammation 

Wang, Z. #, Chen, Z. #, Wang, X., Hu, Y., Kong, J., Lai, J., Li, T., Hu, B., Zhang, Y., Zheng, X., Liu, X., Wang, S., Ye, S., Zhou, Q., and Zheng, C. (2022) Sappanone a prevents diabetic kidney disease by inhibiting kidney inflammation and fibrosis via the NF-kappaB signaling pathway. Front Pharmacol 13, 953004

Chen, Z., Wu, C., Liu, Y., Li, H., Zhu, Y., Huang, C., Lin, H., Qiao, Q., Huang, M., Zhu, Q., and Wang, L. (2020) ELABELA attenuates deoxycorticosterone acetate/salt-induced hypertension and renal injury by inhibition of NADPH oxidase/ROS/NLRP3 inflammasome pathway. Cell Death Dis 11, 698


Current Program

The protective role of ELA on diabetes induced glomerular endothelial cells injury and underlying mechanisms. Funding Source: National Natural Science Foundation of China, 82100748, 2022.01-2024.12

The beneficial role and underlying mechanisms of ELA on prevention of podocyte EMT and diabetic glomerular sclerosis via inhibition of pyroptosis. Funding Source: Zhejiang Provincial Natural Science Foundation. LQ22H050005, 2022.01-2024.12


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