Zhang Yanzhen, M.D.

Position:Chair of General Dentistry

Department:General Dentistry

Medical School:West China College of Stomatology Sichuan University, China

Academic Rank:Chief Physician


Appointment

Clinical / Research Interests

Esthetic dentistry, prosthodontics, temporomandibular joint disorders, minimally invasive dental implantology.

Professional Highlights

Zhejiang Scientific and Technological Progress Award, Second Prize

Zhejiang Provincial Department of Health and Science Innovation Award, Second Prize

Zhejiang Provincial Science Progress Award, Third Prize

Professional Appointments

Member, National Database of Science and Technology Experts

Review Expert, National Natural Science Foundation of China

Member, Standing Committee, Prosthodontics Committee, Chinese Stomatological Association

Executive Member of the Committee, Zhejiang Stomatological Association 

Vice Chair, Prosthodontics Committee, Zhejiang Stomatological Association

Committee Member, Oral Implantology Committee, Zhejiang Stomatological Association

Editor, West China Journal of Stomatology

Editor, Chinese Journal of Dental Materials Devices


Education Experience

Research Summary

Dr Zhang's research interests are concerned mainly with nanotechnology, tissue regeneration and biomedical engineering related to dentistry. Many of her laboratory discoveries ffrom basic researches have transformed into clinical application. Her current research fields include:

1.  Basic metabolic processes and signaling pathways of bone regeneration;

2. Stem cell biology and oral tissue engineering;

3. Treatment alternatives of Temporomandibular Joint Disorders (conservative treatment and herbal medicine topical application);

4. Tooth auto-transplantation.

Publications

Xia, J.J., Ge, Z.Y., Fu, X.H. and Zhang, Y.Z., 2020. Autotransplantation of third molars with completely formed roots to replace compromised molars with the computer‐aided rapid prototyping. Journal of Esthetic and Restorative Dentistry, 32(3), pp.265-271.

Ge, Z.Y., Yang, L.M., Xia, J.J., Fu, X.H. and Zhang, Y.Z., 2020. Possible aerosol transmission of COVID-19 and special precautions in dentistry. Journal of Zhejiang University-SCIENCE B, 21(5),pp.361-368.

Fu, X., Feng, Y., Shao, B. and Zhang, Y.Z., 2019. Activation of the ERK/Creb/Bcl‑2 pathway protects periodontal ligament stem cells against hydrogen peroxide‑induced oxidative stress. Molecular medicine reports, 19(5), pp.3649-3657.

Zhao, Y.Y., Chu, Q., Shi, X.E., Zheng, X.D., Shen, X.T. and Zhang, Y.Z., 2018. Toxicity testing of four silver nanoparticle-coated dental castings in 3-D LO2 cell cultures. Journal of Zhejiang University-SCIENCE B, 19(2), pp.159-167.

Shen, X.T., Zhang, Y.Z., Xiao, F., Zhu, J. and Zheng, X.D., 2017. Effects on cytotoxicity and antibacterial properties of the incorporations of silver nanoparticles into the surface coating of dental alloys. Journal of Zhejiang University-SCIENCE B, 18(7), pp.615-625.

Hong, X.P., Zhu, Y. and Zhang, Y.Z., 2012. Electrocatalytic response of poly (cobalt tetraaminophthalocyanine)/multi-walled carbon nanotubes-Nafion modified electrode toward sulfadiazine in urine. Journal of Zhejiang University SCIENCE B, 13(6), pp.503-510.

Huang, B., Yin, Y., Lu, L., Ding, H., Wang, L., Yu, T., Zhu, J.J., Zheng, X.D. and Zhang, Y.Z., 2010. Preparation of high-affinity rabbit monoclonal antibodies for ciprofloxacin and development of an indirect competitive ELISA for residues in milk. Journal of Zhejiang University Science B, 11(10), pp.812-818.

Zhang, Y.Z., Zhou, Y.C., Liu, L. and Zhu, Y., 2007. Simultaneous determination of fluoride, chloride, sulfate, phosphate, monofluorophosphate, glycerophosphate, sorbate, and saccharin in gargles by ion chromatography. Journal of Zhejiang University Science B, 8(7), pp.507-511.

Zhang, Y.Z., Zhou, Y.C., Liu, L., Lu, Y. and Hirofumi, Y., 2007. Stabilization of an abutment under a rigidly fixed bridge by holographical-speckle interferometry. Journal of Zhejiang University SCIENCE B, 8(6), pp.416-421.

Zhang, Y.Z., Zhang, Z.Y., Zhou, Y.C., Liu, L. and Zhu, Y., 2007. Determination of fluorinated quinolone antibacterials by ion chromatography with fluorescence detection. Journal of Zhejiang University SCIENCE B, 8(5), pp.302-306.

Yao, J.F., Bao, C.Y., Sun, R., Zhang, Y.Z., Sun, L.Y., Ou, G.M. and Xiong, C.D., 2007. Exploring the Osteoinductivity of Calcium Phosphate Ceramics/PLA or Collagen Composites. In Key Engineering Materials,Vol. 336, pp. 1638-1641.

Yao, J.F., Zhang, Y.Z., Bao, C.Y., Sun, L.Y., Hao, X.M., Fan, H.S. and Zhang, X.D., 2007. Reconstructing box-like Bone defect of mandible with in vivo tissue engineering bone. In Key Engineering Materials Vol. 330, pp. 1165-1168.

Bao, C.Y., Zhang, Y.Z., Wang, H.L., Luo, J.M., Tan, Y.F., Fan, H.S. and Zhang, X.D., 2006. Stress analysis and optimizing of osteoinductive Ca-P ceramics and net-cage-structured titanium alloy in dog segmental femoral defect reparation. In Key Engineering Materials Vol. 309, pp. 231-234.


Current Program

Research on molecular mechanism of osteogenesis and adipogenesis of aged bone marrow-derived mesenchymal stem cells on Sr-modified nanostructured titanium surface. Funding Source: Natural Science Foundation of Zhejiang.

Oral application of Gushukang Capsule combined with occlusal appliance in treatment of temporomandibular joint disorder. Funding Source: Zhejiang Traditional Chinese Medicine Scientific Research Foundation Project.

Topical application of Yunnan Baiyao "Baoxianzi" combined with occlusal appliance in the treatment of temporomandibular joint disorder. Funding Source: Zhejiang Traditional Chinese Medicine Scientific Research Foundation Project. 

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