Zhu Lei, M.D., Ph.D.

Department:Clinical Laboratory Medicine

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Associate Chief Technician


Clinical / Research Interests

Bone marrow morphology, pathology, and exfoliative cytology, especially diagnosis of hematologic disorders;

Systematic analysis of tumors of the hematopoietic and lymphoid tissues by means of morphology, immunology, cytogenetics and molecular biology.

Professional Highlights

Innovation of Medicine, Health Science and Technology of Zhejiang Province, Second Prize, 2009 

Zhejiang Provincial Award for Science and Technology Innovation, Third Prize, 2011

Professional Appointments

Member, Zhejiang Physicians Association

Member, Chinese Anti-Cancer Association


Education Experience

Research Summary

Publications

Lei Zhu, Xin He, Haojie Dong, Jie Sun, Hanying Wang, Yinghui Zhu, Feiteng Huang, Jingying Zou, Zexin Chen, XiaoyingZhao, Ling Li. Protein arginine methyltransferase 1 is required for maintenance of normal adult hematopoiesis. Int. J. Biol.Sci, 2019,15 (10): 2763-2773. 

He X, Zhu L, Li S, Chen Z, Zhao X. Loperamide,  antidiarrheal agent, induces  apoptosis  and  DNA  damage  in  leukemia  cells. Oncol Lett. 2018 ; 15(1):765-774.

Zhu L, Zhao XY, Qiu X. Relationship between changes of bone mineral density and bone marrow pathology in ovariectomized rats. Journal of Experimental Hematology. 2014;22(3):617-622.

Zhu L, Lu XG, Zhao XY, et al. The diagnosis value of morphology changes of pleomorphic megakaryocytes in bone marrow smears and bone marrow sections in chronic myeloproliferative disorders. Chin J Lab Med, 2010;33(2).143-148.

Zhu L, Lu XG, Zhao XY, The relationship between the SLL, MBL and CLL. Chin J Lab Med. 2010;33(12).1190-1192.

Zhu L, Zhao XY, Lu XG. Relationship between changes of bone mineral densitiy and bone marrow angiogenesis in ovariectomized rats. Chinese Journal of Pathophysiology. 2009;25(9):1801-1805.

Zhu L, Zhao XY, Lu XG. Ovarietomy-associated changes in bone mineral density and bone marrow hematopoiesis in rats. International Journal of Experimental Pathology. 2009,90(2):512-519.

ZHU Lei,LU Xing-guo,ZHANG Xiao-hong,XU Gen-bo,ZHAO Xiao-ying.Primary hyperparathyroidism and its morphology changes in bone marrow:one case report. Chin J Endocrinol Metab. 2009,25(3):354-355.

Zhu Lei, Lu Xingguo, Zhang Xiaohong, et al. Research on the morphology of megakaryocytes extrusion of nucleus and nucleocytoplasmic separation. Chin J Lab Med ,2005, 28(2): 163-166.

Zhu Lei, Lu Xingguo, Zhu Zhengguo. Bone marrow biopsy analysis of myelodysplastic syndrome with myelofibrosis. Laboratory Medicine. 2005,20(6). 602-603.

Zhu Lei, Lu Xingguo. Special types of myelodysplastic syndromes (WHO: new classification of myelodysplastic syndromes). Zhejiang Medical Journal. 2003,25(12), 767-769.


Current Program

The mechanism study of PI3K/AKT/mTOR signaling pathway regulates autophagy HIF-1 alpha is involved in bortezomib resistant in multiple myeloma. Funding Source: Zhejiang Medical and Health Research Foundation Project.

Find People

Search by Family Name

Find A Department

Search by Departments