Yu Risheng, M.D., Ph.D.

Position:Interim Chair of Radiology

Department:Radiology

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Chief Physician 


Appointment

Clinical / Research Interests

Basic clinical application of abdominal imaging; basic research of molecular imaging; application and exploitation of new MRI technology.


Professional Highlights

Professional Appointments

Member, Radiology Committee, Zhejiang Medical Association

Abdominal Imaging Group, Imaging Committee, Zhejiang Association of Integrated Traditional Chinese and Western Medicine

Memember, Imaging Committee, IBD Chinese Union

Member, Digestive Diseases Committee, Chinese Association of Radiologists 

Member, Pancreatic Diseases Committee, Chinese Research Hospital Association

Member, Biomedical Engineering of Zhejiang Society 

Member, IBD Committee, Chinese Medical Education Association 

Member, International Association of Pelvic Floor Disorder

Education Experience

Research Summary

Dr. Yu is mainly engaged in imaging diagnosis, such as abdominal imaging, basic research of molecular imaging, and application of new MRI technology. Dr. Yu has been and is in charge of 10 national, provincial and bureau-level projects, including three funded by the National Natural Science Foundation of China, one by the Natural Science Foundation of Zhejiang Province, one by the Zhejiang University, and two funded separately by Zhejiang Provincial Science and Technology Department and Education Department. Dr. Yu has published more than 100 articles in local and international magazines. More than 50 of these articles were embodied by SCI as first-author or corresponding-author. And more than 40 papers had been published on Chinese journals as first author.

Publications

Zhang Q#, Lu YF#, Xu XL, Li SJ, Du YZ*, Yu RS *. MR molecular imaging of HCC employing a regulated ferritin gene carried by a modified polycation vector. International Journal of Nanomedicine. 2019.5.2, 2019(Vol14): 3189~3201. (corresponding author)

Zhang NN#, Yu RS#, Xu M#, Cheng XY, Chen CM, Xu XL, Lu CY, Lu KJ, Chen MJ, Zhu ML, Weng QY, Hui JG, Zhang Q, Du YZ*, Ji JS*. Visual targeted therapy of hepatic cancer using homing peptide modified calcium phosphate nanoparticles loading doxorubicin guided by T1 weighted MRI. Nanomedicine: Nanotechnology, Biology, and Medicine. 2018,14(7):2167-2178.

Zhu XL#, Deng XY#, Lu CY#, Chen Y, Jie LY, Zhang Q, Li W, Wang ZH*, Du YZ*, Yu RS*. SPIO-loaded nanostructured lipid carriers as liver-targeted molecular T2-weighted MRI contrast agent. Quant Imaging Med Surg. 2018. doi:10.21037/qims.2018.09.03 (corresponding author)

Lu CY#, Ji JS#, Zhu XL, Tang PF, Zhang Q, Zhang NN, Wang ZH, Wang XJ, Chen WQ, Hu JB, Du YZ*, Yu RS*. T2-weighted magnetic resonance imaging of hepatic tumor guided by spio-loaded nanostructured lipid carriers and ferritin reporter genes. ACS Appl Mater Interfaces. 2017,9(41):35548-35561. (corresponding author)

Situ JQ #, Wang XJ#, Zhu XL, Xu XL, Kang XQ, Hu JB, Lu CY, Ying XY, Yu RS*, You J & Du YZ*. Multifunctional SPIO/DOX-loaded A54 homing peptide functionalized dextran-g-plga micelles for tumor therapy and mr imaging. Sci Rep. 2016, 6: 35910. (corresponding author)

Situ JQ, Ye YQ, Zhu XL, Yu RS*, You J, Yuan H, Hu FQ, Du YZ*. Specific targeting of A54 homing peptide-functionalized dextran-g-poly (lactic-co-glycolic acid) micelles to tumor cells. International Journal of Nanomedicine, 2015,10:665-675. (corresponding author)

Zhu XL, Du YZ, Yu RS, Liu P, Shi D, Chen Y, Wang Y, Huang FF. Galactosylated chitosan oligosaccharide nanoparticles for hepatocellular carcinoma cell-targeted delivery of adenosine triphosphate. Int J Mol Sci. 2013, 14: 15755-15766. (corresponding author)

Hao L, Yu RS, Cui F, Ren XC, Xu HB, Xu KY. [Breast cancer subtypes based on ER/PR and Her2 expression: comparison of mr imaging features]. Zhonghua Yi Xue Za Zhi. 2013; 93: 819-823. Chinese. (corresponding author)

Liu WB, Yu HL, Jiang B, Zheng LL, Yu SH, Pan B, Yu RS. [Correlation of neurochemical metabolism with memory function in young adult patients with first-episode depression studied with proton magnetic resonance spectroscopy]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2013, 42: 450-5. Chinese. (corresponding author)

Fan J, Tan Y, Jie L, Wu X, Yu R, Zhang M. Biological activity and magnetic resonance imaging of superparamagnetic iron oxide nanoparticles-labeled adipose-derived stem cells. Stem Cell Res Ther. 2013, 4: 44. 

Jie LY, Cai LL, Wang LJ, Ying XY, Yu RS, Zhang MM, Du YZ. Actively-targeted LTVSPWY peptide-modified magnetic nanoparticles for tumor imaging. Int J Nanomedicine. 2012; 7: 3981-3989.

Xu XF, Chen Y, Yu RS, Huang K, Chen YH, Liu R. CT and MRI findings of central nervous system complications of leukemia. Chin J Radiol. 2011, 45: 37-41.(corresponding author)

Qu H, Yu RS, Cu F, Zhu B. Chest CT features of microscopic polyangiitis. Chin J Radiol. 2011, 45: 441-444. (corresponding author)

Chen Y, Yu RS, Qiu LL, Jiang DY, Tan YB, Fu YB. Contrast-enhanced multiple-phase imaging features in hepatic epithelioid hemangioendothelioma. World J Gastroenterol 2011, 17 (30):3544-53. (corresponding author)

Qiu LL, Yu RS, Chen Y, Zhang Q. Sarcomas of abdominal organs: computed tomography and  magnetic resonance imaging findings. Semin Ultrasound CT MR. 2011;32(5):405-21. (corresponding author)

Xu XF, Yu RS, Liu R, Sun JZ, Chen YH, Chen J, Zhang MM. Biochemical metabolic changes detected by phosphorus-31 MR spectroscopy in liver of fasting rabbits. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2010,39(2):143-9. Chinese. (corresponding author

Sun JZ, Wang ZK, Yu RS, Huang LS, Xu XF, Zhang MM. Evaluation of biochemical metabolites by 31P MR spectroscopy in leukemic infiltration of liver. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2010;39(2):150-6. Chinese. 

Du YZ, Ying XY, Wang L, Zhai Y, Yuan H, Yu RS, Hu FQ. Sustained release of ATP encapsulated in chitosan oligosaccharide nanoparticles.Int J Pharm. 2010,15;392(1-2):164-9.

Yu RS, Chen Y, Wang LH, Xu XF, Jiang DY. A large functional somatostatinoma in the pancreatic tail: atypical CT appearances.Turk J Gastroenterol. 2009, 20(4):291-4.

Chen ZH, Yu RS, Dong F, Wang XJ. CT findings of an ectopic pancreas in the anterior mediastinum. Korean J Radiol. 2009;10(5):527-530. (corresponding author)

Yu RS, Hao L, Dong F, Mao JS, Sun JZ, Chen Y, Lin M, Wang ZK, Ding WH. Biochemical metabolic changes assessed by 31P magnetic resonance spectroscopy after radiation-induced hepatic injury in rabbits. World J Gastroenterol, 2009, 14;15(22):2723-30.

Yu RS, Wang JW, Chen Y, Ding WH, Xu XF, Chen LR. A case of primary malignant fibrous histiocytoma of the pancreas: CT and MRI findings. World J Gastroenterol, 2008, 14;14(18):2942-2945. 

Yu RS, Chen Y, Jiang B, Wang LH, Xu XF. Primary hepatic sarcomas: CT findings. Eur Radiol, 2008, 18(10):2196-2205. 

Yu RS, Wang ZK, Sun JZ, Chen LR. Computed tomography of pancreatic implantation with malignant transformation of leiomyomatosis peritonealis disseminata in a man. Dig Dis Sci, 2007, 52(8):1954-1957. 

Yu RS, Sun JZ. Pancreatic schwannoma: CT findings. Abdom Imaging, 2006,30(1-2): 103-105. 

Yu RS, Zhang WM, Liu YQ. CT diagnosis of 52 patients with lymphoma in the abdominal lymph nodes. World J Gastroenterol, 2006, 12 (28) :7869-7873. 

Yu RS, Zhang SZ, Wu JJ, Li RF. Imaging diagnosis of 12 patients with hepatic tuberculosis. World J Gastroenterol, 2004, 10 (11): 1639-1642.

Yu RS, Zhang SZ, Hua JM. Imaging findings of splenic hamartoma. World J Gastroenterol 2004, 10 (17): 2613-2615.

Jiang B, He WL, Yu RS, Chao M. Magnetic resonance behavior of lipiodol--an experimental study. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2004;33(3):250-4. Chinese. (corresponding author)

Yu RS, Chen Y, Jiang B, Wang LH, Xu XF. Hepatic angiosarcoma: CT findings. Chinese Medical Journal, 2003, 116(2):318-320. 

Yu RS, Liu Y. Gallbladder tuberculosis: case report. Chinese Medical Journal, 2002, (8):1159-1161.

Yu R, Tong B, Li R. Imaging diagnosis of intestinal tuberculosis. Zhonghua Jie He He Hu Xi Za Zhi. 2001;24(7):404-6. Chinese. 

Yu R, Yin J, Wei F. Imaging diagnosis for abdominal tuberculous lymphadenopathy. Zhonghua Jie He He Hu Xi Za Zhi. 2000;23(12):715-7. Chinese.


Current Program

Experimental study of hepatocyte-targeted phosphorus-31 magnetic resonance spectroscopy using chitosan nanoparticles for the diagnosis of hepatic diseases. Funding Source: National Natural Science Foundation of China.

Experimental study on SPIO-loaded solid lipid nanoparticles to target hepatocytes and Kupffer cells as a novel molecular imaging contrast agent for magnetic resonance imaging. Funding Source: National Natural Science Foundation of China.

The diagnosis of hepatoma cells with MR molecular imaging by specific bidirectional targeting. Funding Source: National Natural Science Foundation of China.

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