Ye Juan, M.D., Ph.D.

Position:Vice Chair of Ophthalmology

DepartmentOphthalmology

Medical SchoolZhejiang University School of Medicine, China

Academic RankProfessor, Chief Physician


Appointment

Clinical / Research Interests

Ophthalmic plastics, ocular oncology and ocular surface diseases.

Professional Highlights

Zhejiang Medicine and Health Science and Technology Award, Second Prize

Zhejiang Scientific and Technological Progress Award, First Prize

State Scientific and Technological Progress Award, Second Prize

Zhejiang Scientific and Technological Progress Award, Second Prize


Professional Appointments

Committee Member, Society of Ophthalmology, Chinese Medical Association, 2018-present

Chairman-Elect, Society of Ophthalmology, Zhejiang Medical Association, 2018-present

Member, Asia Pacific Society of Ophthalmic Plastic & Reconstructive Surgery, Life time

Member, Youth Committee of the Chinese Medical Association, 2011-present

Vice Chairman, Ophthalmological Society, Zhejiang Medical Association, 2009-present

Editor, Chinese Journal of Ophthalmology, 2009-present


Education Experience

Research Summary

Publications

Jing Cao#, Kun You#, Kai Jin, Lixia Lou, Yao Wang, Menglu Chen, Xiangji Pan, Ji Shao, Zhaoan Su, Jian Wu*, Juan Ye*. Prediction of Response to Anti-VEGF Treatment in Diabetic Macular Edema Using an OCT-based Machine Learning Method. Acta Ophthalmologica. 2020 Jun 22. 

Qi Miao, Yufeng Xu, Houfa Yin, Huina Zhang, Juan Ye*. KRT8 phosphorylation regulates the epithelial-mesenchymal transition in retinal pigment epithelial cells through autophagy modulation. J Cell Mol Med. 2020; 24(5):3217-3228.

Peifang Xu, Xue Feng, Honghao Zheng, Zhongwei Feng, Zhisheng Fu*, Changyou Gao*, Juan Ye*. A tarsus construct of a novel branched polyethylene with good elasticity for eyelid reconstruction in vivo. Regenerative Biomaterials. 2020: 1–11. 

Xiangji Pan#, Kai Jin#, Jing Cao#, Zhifang Liu, Jian Wu, Kun You, Yifei Lu, Yufeng Xu, Zhaoan Su, Jiekai Jiang, Ke Yao, Juan Ye*. Multi-label Classification of Retinal Lesions in Diabetic Retinopathy for Automatic Analysis of Fundus Fluorescein Angiography Based on Deep Learning. Graefes Arch Clin Exp Ophthalmol. 2020; 258:779–785. 

Qingyao Ning, Xiaoyao Yu, Qi Gao, Jiajun Xie, Chunlei Yao, Kun Zhou*, Juan Ye*. An accurate interactive segmentation and volume calculation of orbital soft tissue for orbital reconstruction after enucleation. BMC Ophthalmology. 2019; 19:256. 

Tiepei Zhu#, Enhui Li#, Jinyu Li, Xizhe Dai, Huina Zhang, Binbin Chen, Panpan Ye, Zhaoan Su, Juan Ye*. Comparison of Projection-Resolved Optical Coherence Tomography Angiography-Based Metrics for the Early Detection of Retinal Microvascular Impairments in Diabetes Mellitus. Retina. 2019 Oct 01; 00: 1-10.

Jingyi Wang, Changjun Wang, Kai Jin, Xianyan Yang, Lingling Gao, Chunlei Yao, Xizhe Dai, Jinjing He, Changyou Gao, Juan Ye*, Peng Li*, Zhongru Gou*. Simultaneous enhancement of vascularization and contact-active antibacterial activity in diopside-based ceramic orbital implants. Materials Science & Engineering C. 2019; 105: 110036.

Wang L, Ding L, Liu Z, Sun L, Chen L, Jia R, Dai X, Cao J, Ye J*. Automated identification of malignancy in whole-slide pathological images: identification of eyelid malignant melanoma in gigapixel pathological slides using deep learning. Br J Ophthalmol. 2020; 104(3):318-323.

Peifang Xu#, Qi Gao#, Xue Feng, Lixia Lou, Tiepei Zhu, Changyou Gao*, Juan Ye*. A biomimetic tarso-conjunctival biphasic scaffold for eyelid reconstruction in vivo. Biomaterials Science. 2019; 7(8): 3373-3385.

Lixia Lou, Longzhao Yang, Xin Ye, Yan Zhu, Shaoze Wang, Lingling Sun, Dahong Qian*, Juan Ye*. A Novel Approach for Automated Eyelid Measurements in Blepharoptosis Using Digital Image Analysis. Curr Eye Res. 2019. 44(10):1075-1079.

Tiepei Zhu#, Jinlian Ma#, Jinyu Li, Xizhe Dai, Panpan Ye, Zhaoan Su, Dexing Kong, Juan Ye*. Multifractal and lacunarity analyses of microvascular morphology in eyes with diabetic retinopathy: A projection artifact resolved optical coherence tomography angiography study. Microcirculation. 2019; 26(3):e12519.

Qi Miao, Yufeng Xu, Huina Zhang, Peifang Xu, Juan Ye*. Cigarette smoke induces ROS mediated autophagy impairment in human corneal epithelial cells. Environmental Pollution. 2019; 245:389-397.

Xin Ye, Shaoze Wang, Yan Zhu, Huifeng Shao, Lixia Lou, Dahong Qian*, Juan Ye*. Automatic Design and Fabrication of a Custom Ocular Prosthesis Using 3D Volume Difference Reconstruction (VDR). IEEE Access. 2018; 6:14339-14346.

Kai Jin#, Mei Zhou#, Shaoze Wang, Lixia Lou, Yufeng Xu, Juan Ye*, Dahong Qian*. Computer-aided diagnosis based on enhancement of degraded fundus photographs. Acta Ophthalmologica. 2018, 96(3): E320-E326. 

Jiajun Xie#, Changjun Wang, Qingyao Ning, Qi Gao, Changyou Gao, Zhongru Gou, Juan Ye*. A new strategy to sustained release of ocular drugs by one-step drug-loaded microcapsule manufacturing in hydrogel punctal plugs. Graefes Arch Clin Exp Ophthalmol. 2017; 255: 2173–2184.

Kai Jin#, Haitong Lu, Zhaoan Su, Chuming Cheng, Juan Ye*, Dahong Qian*. Telemedicine screening of retinal diseases with a handheld portable non-mydriatic fundus camera. BMC Ophthalmology. 2017; 17:89. 

Huina Zhang#, Han Wu#, Jun Yang, Juan Ye*. Sodium perbarate and benzalkonium chloride induce DNA damage in Chang conjunctival epithelial cells. Cutaneous and Ocular Toxicology. 2017; 36(4):336-342.

Yufeng Xu, Shengzhan Wang, Qi Miao, Kai Jin, Lixia Lou, Xin Ye, Yan Xi, Juan Ye*. Protective Role of Hinokitiol Against H2O2 Induced Injury in Human Corneal Epithelium. Current Eye Research. 2017; 42(1):47-53.

Kai Jin, Bo Li, Lixia Lou, Yufeng Xu, Xin Ye, Ke Yao, Changyou Gao*, Juan Ye*. In vivo vascularization of MSCs-loaded porous hydroxyapatite constructs coated with VEGF-functionalized collagen/heparin multilayers. Scientific Reports. 2016; 6:19871.

Shaoze Wang, Kai Jin, Haitong Lu, Chuming Cheng, Juan Ye*, Dahong Qian*. Human visual system-based fundus image quality assessment of portable fundus camera photographs. IEEE Transactions on Medical Imaging. 2016; 35(4):1046-1055.

Qi Gao, Bin Hu, Qingyao Ning, Chen Ye, Jiajun Xie, Juan Ye*, Changyou Gao*. A primary study of poly(propylene fumarate)-2-hydroxyethyl methacrylate copolymer scaffolds for tarsal plate repair and reconstruction in rabbit eyelids. Journal of Materials Chemistry B. 2015; 3: 4052-4062.

Ye J*, Xu Y-F, He J-J, Lou L-X. Association between aspirin use and age-related macular degeneration: a meta-analysis. Invest Ophthalmol Vis Sci. 2014; 55(4):2687-2696.

Juan Ye*, Xin Shi, Xiaoyi Chen, Jiajun Xie, Changjun Wang, Ke Yao, Changyou Gao, and Zhongru Gou. Chitosan-modified, collagen-based biomimetic nanofibrous membranes as selective cell adhering wound dressing in the treatment of chemical burned cornea. Journal of Materials Chemistry B.2014;2: 4226-4236. 

Han Wu, Huina Zhang, Peiwei Li, Tao Gao, Jijian Lin, Jun Yang, Yihua Wu, Juan Ye*. Association between dietary carbohydrate intake and dietary glycemic index and risk of age-related cataract: A meta-analysis. Invest Ophthalmol Vis Sci. 2014; 55:3660–3668.

Juan Ye*, Jinjing He, Changjun Wang, Han Wu, Xin Shi, Huina Zhang, Jiajun Xie, and Sang Yeul Lee. Smoking and Risk of Age-Related Cataract: A Meta-Analysis. Invest Ophthalmol Vis Sci. 2012; 53(7): 3885-3895. 

Ye J*, Wang C, Su P, Wu H, Zhou Y, Yao K, Yang J, Gou Z. Biochemically active hydrosol as a means of collecting electrospun microcapsules for drug delivery. Journal of Materials Chemistry. 2010; 20:9025-9028.

Ye Juan, Kook KH, Lee SY*. Evaluation of computer-based volume measurement and porous polyethylene channel implants in reconstruction of large orbital wall fractures. Invest Ophthalmol Vis Sci. 2006; 47(2): 509-513.



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