Yan Yaping, M.D., Ph.D.


Medical School:Zhejiang University School of Medicine, China

Academic Rank:Associate Chief Physician


Clinical / Research Interests

Neurodegenerative diseases of nervous system, especially Alzheimer's disease and Parkinson's disease.

Professional Highlights

Professional Appointments

Member, Youth Committee, Chinese Apoplexy Association of Severe Cerebral Vascular Diseases, 2018-present

Education Experience

Research Summary


Yan YP, Zhang B, Shen T, Si XL, Guo ZY, Tian J, Xu CY, Zhang BR. Study of GCH1 and TH genes in Chinese patients with Parkinson's disease. Neurobiol Aging. 2018 Aug;68:159.e3-159.e6.

Yan YP, Zhang B, Mao YF, Guo ZY, Tian J, Zhao GH, Pu JL, Luo W, Ouyang ZY, Zhang BR. A novel tyrosine hydroxylase variant in a group of Chinese patients with dopa-responsive dystonia. Int J Neurosci. 2017 Aug;127(8):694-700.

Mao YF, Guo Z, Zheng T, Jiang Y, Yan Y, Yin X, Chen Y, Zhang B.Intranasal insulin alleviates cognitive deficits and amyloid pathology in young adult APPswe/PS1dE9 mice. Aging Cell. 2016 Jul 26. doi: 10.1111/acel.12498.

Tian J, Yan YP, Zhou R, Lou HF, Rong Y, Zhang BR. Soluble N-terminal fragment of mutant Huntingtin protein impairs mitochondrial axonal transport in cultured hippocampal neurons. Neurosci Bull. 2014 Feb;30(1):74-80.

Yan YP, Mo XY, Tian J, Zhao GH, Yin XZ, Jin FY, Zhang BR*. An association between the PARK16 locus and Parkinson's disease in a cohort from eastern China.Parkinsonism Relat Disord. 2011,17(10):737-739. 

Yan Y, Tian J, Mo X, Zhao G, Yin X, Pu J, Zhang B*. Genetic variants in the RAB7L1 and SLC41A1 genes of the PARK16 locus in Chinese Parkinson's disease patients. Int J Neurosci. 2011,121(11):632-636.

Current Program

The effect of SLC41A1 gene (located in PARK16) and its variants on the cellular ionic homeostasis and its function. Funding Source: National Natural Science Foundation of China.

Clinical analysis and gene detection of frontotemporal dementia. Funding Source: Zhejiang Medical and Health Science and Technology Program.

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