Yan Xiaofeng, M.S.

Position:Honorary Chair of Pharmacy

Department:Pharmacy

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Chief Pharmacist


Clinical / Research Interests

Molecular mechanisms of Rac1 signaling in the regulation of cigarette induced airway epithelial mesenchymal cell transformation.

Professional Highlights

Leadership Award, Zhejiang Province Pharmaceutical Administration

Professional Appointments

Senior Member, Chinese Pharmaceutical Association 

Editor Board Member, Chinese Journal of Modern Applied Pharmacy 

Editor Board Member, Chinese Journal of Hospital Pharmacy 

Editor Board Member, Herald of Medicine and World Clinical Drugs 

Vice Chairman, Society of Clinical Pharmacy, Zhejiang Medical Association 

Vice Chairman, Society of Hospital Pharmacy, Zhejiang Pharmaceutical Association 

Vice Chairman, Committee of Zhejiang Hospital Pharmaceutical Administration


Education Experience

Research Summary

Publications

Hu Y, Ping Y, Li L, Xu H, Yan X, Dai H. A retrospective study of risk factors for carbapenem-resistant Klebsiella pneumoniae acquisition among ICU patients.J Infect Dev Ctries. 2016 Mar 31;10(3):208-13.

Jiang JX, Zhang SJ, Xiong YK, Jia YL, Sun YH, Lin XX, Shen HJ, Xie QM, Yan XF. EETs Attenuate Ox-LDL-Induced LTB4 Production and Activity by Inhibiting p38 MAPK Phosphorylation and 5-LO/BLT1 Receptor Expression in Rat Pulmonary Arterial Endothelial Cells.PLoS One. 2015 Jun 2;10(6):e0128278.

Shen HJ, Sun YH, Zhang SJ, Jiang JX, Dong XW, Jia YL, Shen J, Guan Y, Zhang LH, Li FF, Lin XX, Wu XM, Xie QM, Yan XF. Cigarette smoke-induced alveolar epithelial-mesenchymal transition is mediated by Rac1 activation. Biochim Biophys Acta. 2014 Jun;1840(6):1838-49.

Jiang JX, Zhang SJ, Liu YN, Lin XX, Sun YH, Shen HJ, Yan XF, Xie QM. EETs alleviate ox-LDL-induced inflammation by inhibiting LOX-1 receptor expression in rat pulmonary arterial endothelial cells.Eur J Pharmacol. 2014 Mar 15;727:43-51.

Xu HM, Cai HW, Dai HB, Yan XF, Zhou Q, Xu G, Huang ZQ, Mao W. Use of evidence-based pharmacotherapy for secondary prevention of coronary heart disease: a Chinese medicine hospital versus a general hospital.Chin J Integr Med. 2014 May;20(5):375-80.

Zhang LH, Jia YL, Lin XX, Zhang HQ, Dong XW, Zhao JM, Shen J, Shen HJ, Li FF, Yan XF, Li W, Zhao YQ, Xie QM. AD-1, a novel ginsenoside derivative, shows anti-lung cancer activity via activation of p38 MAPK pathway and generation of reactive oxygen species.Biochim Biophys Acta. 2013 Aug;1830(8):4148-59.

Cai H, Dai H, Hu Y, Yan X, Xu H. Pharmacist care and the management of coronary heart disease: a systematic review of randomized controlled trials.BMC Health Serv Res. 2013 Nov 4;13:461.

Yan XF, Zhang ZM, Yao HY, Guan Y, Zhu JP, Zhang LH, Jia YL, Wang RW. Cardiovascular protection and antioxidant activity of the extracts from the mycelia of Cordyceps sinensis act partially via adenosine receptors. Phytother Res. 2013 Nov;27(11):1597-604.

Hu Y, Li L, Li W, Xu H, He P, Yan X, Dai H. Combination antibiotic therapy versus monotherapy for Pseudomonas aeruginosa bacteraemia: a meta-analysis of retrospective and prospective studies.Int J Antimicrob Agents. 2013 Dec;42(6):492-6.

Xu H, Cai H, Qian Z, Xu G, Yan X, Dai H. Dosing practice of low molecular weight heparins and its efficacy and safety in cardiovascular inpatients: a retrospective study in a Chinese teaching hospital.BMC Cardiovasc Disord. 2012 Dec 5;12:118.

Huang YW, Jian L, Zhang MB, Zhou Q, Yan XF, Hua XD, Zhou Y, He JL. An investigation of oxidative DNA damage in pharmacy technicians exposed to antineoplastic drugs in two Chinese hospitals using the urinary 8-OHdG assay.Biomed Environ Sci. 2012 Feb;25(1):109-16.

Yao HY, Zhang LH, Shen J, Shen HJ, Jia YL, Yan XF, Xie QM. Cyptoporus polysaccharide prevents lipopolysaccharide-induced acute lung injury associated with down-regulating Toll-like receptor 2 expression.J Ethnopharmacol. 2011 Oct 11;137(3):1267-74.

Yao HY, Chen L, Xu C, Wang J, Chen J, Xie QM, Wu X, Yan XF. Inhibition of Rac activity alleviates lipopolysaccharide-induced acute pulmonary injury in mice.Biochim Biophys Acta. 2011 Jul;1810(7):666-74.


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