Xu Wenhong, M.D., Ph.D.

Department:Radiation Oncology

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Chief Physician


Appointment

Clinical / Research Interests

Intensity modulated radiation therapy (IMRT) and stereotactic radiotherapy(SRT);

Precise radiotherapy work of esophageal cancer, lung cancer, breast cancer and head and neck cancer, including brain glioma, nasopharyngeal carcinoma.

Professional Highlights

Professional Appointments

Education Experience

Research Summary

Publications

Wang TT, Wei, QC, Zhang ZT, Lin MT, Chen JJ, Zhou Y, Guo NN, Zhong XC, Xu WH, Liu ZX, Han M*, Gao JQ*. AIE/FRET-Based versatile nanoparticles PEG-Pep-TPE/DOX for cancer therapy and real-time drug release monitoring. Biomaterials Science, 2020, 8(1): 118-124.

Zhong Xincheng#; Xu Wenhong#; Wang Ziting; Guo Wangwei; Guo Ningning; Wang Tiantian; Lin Mengting; Zhang Zhentao; Lu Yiting; Yang Qiyao; Han Min*; Xu Donghang*; Gao Jianqing; Doxorubicin derivative loaded acetal-PEG-PCCL micelles for overcoming multidrug resistance in MCF-7/ADR cells. Drug Development and Industrial Pharmacy. 2019, 45(9): 1556-1564.

Zhang Zhentao; Huangfu Mingyi; Xu Wenhong*; Han Min*; Stimulus -responsive nanoscale delivery systems triggered by the enzymes in the tumor microenvironment. European Journal of Pharmaceutics and Biopharmaceutics. 2019, 137: 122-130. 

Liu HN, Guo NN, Wang TT, Guo WW, Lin MT, Huang-Fu MY, Vakili MR, Xu WH, Chen JJ, Wei QC, Han M, Lavasanifar A, Gao JQ. Mitochondrial Targeted Doxorubicin-Triphenylphosphonium Delivered by Hyaluronic Acid Modified and pH Responsive Nanocarriers to Breast Tumor: in Vitro and in Vivo Studies. Molecular Pharmaceutics, 2018, 15 (3), 882–891.

Liu HN, Guo NN, Guo WW, Huang-Fu MY, Vakili MR, Chen JJ, Xu WH, Wei QC, Han M, Lavasanifar A, Gao JQ. Delivery of mitochondriotropic doxorubicin derivatives using self-assembling hyaluronic acid nanocarriers in doxorubicin-resistant breast cancer, Acta Pharmacol Sin. 2018, 39, 1681-1692.

Xie Z, Guo W, Guo N, Huangfu M, Liu H, Lin M, Xu W, Chen J, Wang T, Wei Q, Han M, Gao J. Targeting tumor hypoxia with stimulus-responsive nanocarriers in overcoming drug resistance and monitoring anticancer efficacy. Acta Biomater. 2018, 71, 351-362.

Xu J, Zhang BC, Li XL, Xu WH, Zhou J, Shen L, Wei QC. Chemosensitization and radiosensitization of a lung cancer cell line A549 induced by a composite polymer micelle. Discov Med. 2016 , 22(119):7-17.

Liu H, Yang W, Gao H, Jiang T, Gu B, Dong QH, Xu WH, Wu SX, Sun XN. Nimotuzumab abrogates acquired radioresistance of KYSESE-150R esophageal cancer cells by inhibiting EG FR signaling and cellular DNA repair. OncoTargets and Therapy. 2015, 8:509-518.

Wenhong Xu, Yue Hu, Jun Li, Xuexin He, Zhixuan Fu, Tao Pan, Hai Liu, Hong He, Weiting Ge, Jiekai Yu, Qichun Wei, Shu Zheng, Yiding Chen, Suzhan Zhang. Study of distinct serum proteomics for the biomarkers discovery in colorectal cancer. Discovery Medicine. 2015, 20(110):239-253.

Wenhong Xu, Yiding Chen, Wenqian He, Zhixuan Fu, Tao Pan, Hong He, Jiekai Yu, Qichun Wei, Shu Zheng, Suzhan Zhang. Protein fingerprint of colorectal cancer, adenomatous polyps, and normal mucosa using ProteinChip analysis on laser capture microdissected cells. Discovery Medicine. 2014,17(95):223-231.

Wenhong Xu, Yue Hu, Xuexin He, Jun Li, Tao Pan, Hai Liu, Xianguo Wu,  Hong He, Weiting Ge, Jiekai Yu, Qichun Wei, Shu Zheng, Suzhan Zhang, Yiding Chen. Serum profiling by mass spectrometry combined with bioinformatics for the biomarkers discovery in diffuse large B-cell lymphoma. Tumor Biology. 2014, 36(3): 2193-2199.

Wenhong Xu, Min Han, Yuanyuan Diao, Tao Pan, Weiting Ge, Hai Liu, Hong He, Hongliang Jiang, Shu Zheng, Suzhan Zhang, Jianqing Gao,Qichun Wei. Doxorubicin encapsulated in micelles enhances radiosensitivity in Doxorubicin -resistant tumor cells. Discovery Medicine. 2014, 18(99):169-177.

Fu Z,Song P,Li D,Yi C,Chen H,Ruan S,Shi Z,Xu W,Fu X,Zheng S. Cancer-associated fibroblasts from invasive breast cancer have an attenuated capacity to secrete collagens. International Journal of Oncology.2014,45: 1479-1488.

Pan T, Sun J, Hu J, Hu Y, Zhou J, Chen Z, Xu D, Xu W, Zheng S, Zhang S. Cytohesins/ARNO: the function in colorectal cancer cells.,PLoS One.2014, 9(3):1-8.

Wen-Hong Xu, Min Han, Qi Dong, Zhi-Xuan Fu, Yuan-Yuan Diao, Hai Liu, Jing Xu, Hong-Liang Jiang, Su-Zhan Zhang, Shu Zheng, Jian-Qing Gao, Qi-Chun Wei. Doxorubicin-mediated radiosensitivity in multicellular spheroids from a lung cancer cell line is enhanced by composite micelle encapsulation. Int J Nanomedicine. 2012, 7: 2661-2671.



Current Program

Zhejiang Medical and Health Science and Technology Plan Project (2016KYB109).

Natural Science Foundation of Zhejiang (LY17H160013).

Find People

Search by Family Name

Find A Department

Search by Departments