Zhang Mao, M.D., Ph.D.

Position:Vice Hospital President, Chair of Emergency Medicine

Department:Emergency Medicine

Medical School:Zhejiang University School of Medicine, China

Academic Rank:Professor, Chief Physician

Clinical / Research Interests

Emergency medicine, critical care medicine, trauma.

Professional Highlights

Zhejiang Scientific and Technological Innovation Award, Second Prize

Professional Appointments

Chair, Institute of Emergency Medicine, Zhejiang University

Committee Member, Chinese Emergency Medicine Association, 2011-present

Secretary-General, Chinese Emergency Medicine Association, 2013-present

President, Zhejiang Emergency Medicine Association, 2013-present

Standing Committee Member, Chinese Trauma Surgeon Association, 2014-present

Committee Member, Chinese Emergency Physician Association, 2015-present

Vice President, Chinese Emergency Medicine Association, 2016-present

Editor, World Journal of Emergency Medicine

Education Experience

Research Summary

Dr. Zhang's research focuses on the care of major trauma, including development of trauma care syetem, early management of major trauma, monitoring and management of complications/organ dysfunction resulting from major trauma. He has successfully developed a new mode of major trauma care in the hospital since 1994, which integrates the emergency room, ICU and general ward for multiple trauma patients. Inspiring effects have been gained and this new mode of trauma care is widely adopted in many Chinese hospitals.


Shen P, Zhang M. Establishment of a swine model of traumatic cardiac arrest induced by hemorrhage and ventricular fibrillation. Journal of International Medical Research, 2020.

Xue YQ, Wu CS, Zhang HC, Du J, Sun JH, Zhang AQ, Zeng L, Zhang M, et al. Value of lung ultrasound score for evaluation of blast lung injury in goats. Chin J Traumatol, 2020, 23(1):38-44. 

Zheng Z, Jiang L, Zhang S, Guervilly C, Zhang M, et al. Neuromuscular blocking agents for acute respiratory distress syndrome: an updated meta-analysis of randomized controlled trials. Respir Res, 2020, 21(1):23. 

Jiang LB, Huang XX, Wu CS, Zhang M. The effects of an enteral nutrition feeding protocol on critically ill patients: A prospective multi-center, before-after study. Journal of Critical Care, 2020, 56: 249-256. 

Wu CS, Xu JF, Jing XH, Chen QJ, Lu X, Qian AY, Wang ML, Li ZL, Zhang M. Effects of therapeutic hypothermia on cerebral tissue oxygen saturation in a swine model of postcardiac arrest. Experimental and Therapeutic Medicine, 2020, 19: 1189-1196 

Wu CS, Xu JF, Jin XH, Chen QJ, Li ZL, Zhang M. Effect of mild hypothermia on lung injury after cardiac arrest in swine based on lung ultrasound. BMC Pulmonary Medicine, 2019, 19(1):198.  

Xu J, Chen Q, Jin X, Wu C, Li Z, Zhou G, Xu Y, Qian A, Li Y, Zhang M. Early initiation of continuous renal replacement therapy induces fast hypothermia and improves post-cardiac arrest syndrome in a porcine model. Shock. 2019, 52(4): 456-467. 

Xu J, Shen P, Gao Y, Xia S, Liu S, Li Z, Zhou G, Xu Y, Zhang M. The effects of the duration of aortic balloon occlusion on outcomes of traumatic cardiac arrest in a porcine model. Shock, 2019, 52(3):e12-e21.

Qian AY, Xu JF, Wu CS, Liu SY, Zhang M. Hypothermia Inhibits Cerebral Necroptosis and NOD-Like Receptor Pyrin Domain Containing 3 Pathway in a Swine Model of Cardiac Arrest. Journal of Surgical Research, 2019, 244: 468-476. 

Gao YZ, Li Q, Wu CS, Liu SY, Zhang M. Use of a Doppler-Based Pulsatility Index to Evaluate Cerebral Hemodynamics in Neurocritical Patients After Hemicraniectomy. J Ultrasound Med, 2019, 9999:1–7. 

Lu X, Wu CS, Gao YZ, Zhang M. Bedside ultrasound assessment of lung reaeration in patients with blunt thoracic injury receiving high-flow nasal cannula oxygen therapy: a retrospective study. J Intensive Care Med, 2018, Dec 4:885066618815649. doi: 10.1177/0885066618815649. 

Gao YZ, Li Qiang, Wu CS, Liu SY, Zhang M. Diagnostic and prognostic value of the optic nerve sheath diameter with respect to the intracranial pressure and neurological outcome of patients following hemicraniectomy. BMC Neurology, 2018, 18:199. 

Xu JF, Jin XH, Chen QJ, Wu CS, Li ZL, Zhou GJ, Xu YA, Qian AY, Li YL, Zhang M. Faster hypothermia induced by esophageal cooling improves early markers of cardiac and neurological injury after cardiac arrest in swine. J Am Heart Assoc, 2018, 7(21): e010283. DOI: 10.1161/JAHA.118.010283.

Liu S, Xu J, Gao Y, Shen P, Xia S, Li Z, Zhang M. Multi-organ protection of ulinastatin in traumatic cardiac arrest model. World J Emerg Surg. 2018, 13: 51. doi: 10.1186 /s13017-018-0212-3. 

Gao YZ, Zhang M. Effect of Intra-aortic Balloon Pump on Reversal of Diastolic Cerebral Flow: Deflated Too Early? Neurocrit Care, 2018, 29(2): 313-314. 

Wu CS, Zheng ZJ, Jiang LB, Gao Y, Xu J, Jin X, Chen Q, Zhang M. The predictive value of bedside ultrasound to restore spontaneous circulation in patients with pulseless electrical activity: a systematic review and meta-analysis. Plos One, 2018, 13(1): e0191636.

Jiang L, Ding W, Zhang M. The progressive increase of the platelet count in a patient with acute severe pancreatitis. Am J Emerg Med. 2017 Jan;35(1):191.e1-191.e2. 

Jiang L, Min J, Zhang M. An "earthworm" in the superior vena cava and right atrium. Intensive Care Med. 2017 Oct;43(10):1516-1517. 

Feng X, Jiang L, Zhang M. The screening criteria for whole-body computed tomography in trauma patients is required. Am J Emerg Med, 2017, 35(7): 1015-1016. 

Yang L, Ye L, Ding J, Zheng Z, Zhang M. Use of a full-body digital X-ray imaging system in acute medical emergencies: a systematic review. Emerg Med J, 2016, 33(2):144-151.

Xu Y, Hong Y, Xu M, Ma K, Fu X, Zhang M, Wang G. Role of Keratinocyte Growth Factor in the Differentiation of Sweat Gland-Like Cells From Human Umbilical Cord-Derived Mesenchymal Stem Cells. Stem Cells Transl Med, 2016, 5(1):106-116.  

Jiang LB, Zhang M, Jiang SY, Ma YF. Early goal-directed resuscitation for patients with severe sepsis and septic shock: a meta-analysis and trial sequential analysis. Scand J Trauma Resusc Emerg Med. 2016 Mar 5;24:23. doi: 10.1186/s13049-016-0214-7.

Ba L, Zhang M, Su L, Cheng ZW, Xu YA. Nine?year change of mortality and discharge against medical advice among major trauma patients in a Chinese Intensive Care Unit. Eur J Trauma Emerg Surg, 2016, 42(1):47-53.

Luo R, Hu J, Jiang L, Zhang M. Prognostic Value of Red Blood Cell Distribution Width in Non-Cardiovascular Critically or Acutely Patients: A Systematic Review. PLoS One. 2016 Dec 9;11(12):e0167000. doi: 10.1371/journal.pone.0167000.

Jiang L, Zhang M. Who will benefit from whole-body computed tomography? Am J Emerg Med. 2016 Sep;34(9):1907-8. 

Jiang L, Ma Y, Zhang M. Can mean platelet volume predict the prognosis of patients with acute kidney injury requiring continuous renal replacement therapy? J Crit Care, 2015, 30(1):207.

Jiang L, Ma Y, Zhang M. Can Red Cell Distribution Width Predict Acute Mesenteric Ischemia? World J Surg, 2015, 39(5): 1325-1326. 

Jiang L, Jiang S, Ma Y, Zhang M. Can Soluble CD73 Predict the Persistent Organ Failure in Patients With Acute Pancreatitis?Crit Care Med, 2015, 43(1):e35-36.

Zhang JG, Fu WL, Qian LN, Lu ML, Zhang M. Evaluation of the effect of a clinical pathway on the quality of simulated pre-hospital cardiopulmonary resuscitation: primary experience from a Chinese pre-hospital care centre. Hong Kong J Emerg Med, 2015, 22(1):14-22. 

Jiang L, Ma Y, Zhang M. Albumin administration in patients with sepsis. Ann Intern Med. 2015,162(4):319.

Zhu W, Jiang L, Jiang S, Ma Y, Zhang M. Real-time continuous glucose monitoring versus conventional glucose monitoring in critically ill patients: a systematic review study protocol. BMJ Open, 2015, 5(1): e006579. 

Jiang LB, Ma YF, Feng X, Zhang M. Can heparin therapy reduce 28-day mortality in adult severe sepsis patients? Crit Care, 2015, 19(1):768.

Jiang L, Ma Y, Zhao C, Shen W, Feng X, Xu Y, Zhang M. Role of Transthoracic Lung Ultrasonography in the Diagnosis of Pulmonary Embolism: A Systematic Review and Meta-Analysis. PLoS One, 2015, 10(6):e0129909. 

Wu D, Zhou X, Ye L, Gan J, Zhang M. Emergency Department Crowding and the Performance of Damage Control Resuscitation in Major Trauma Patients With Hemorrhagic Shock. Acad Emerg Med, 2015, 22(8):915-921.

Jiang L, Zhang M, Ma Y. Ultrasound-Guided Subclavian Vein Catheterization: A Systematic Review and Meta-Analysis: Several Facts Need To Be Noticed. Crit Care Med, 2015, 43(10):e474-e475.

Zheng Z, Jiang L, Ye L, Gao Y, Tang L, Zhang M. The accuracy of presepsin for the diagnosis of sepsis from SIRS: a systematic review and meta-analysis. Ann Intensive Care, 2015, 5(1):48. 

Ye X, Zhang M, Luo RB, et al. Rapid detection of thyroid cartilage fracture by ultrasound in a multiple trauma patient. Intensive Care Med, 2014, 40(7):1021-1022. 

Yang L, Ye L, Zheng Z, Zhang M. Evaluation of the Effectiveness and Safety of the Awakening and Breathing Coordination, Delirium Monitoring/Management, and Early Exercise/Mobility Bundle: Several Confounders to be Considered. Crit Care Med, 2014, 42(10):e680-e681. 

Jiang L, Ma Y, Jiang S, Ye L, Zheng Z, Xu Y, Zhang M. Comparison of whole-body computed tomography vs selective radiological imaging on outcomes in major trauma patients: a meta-analysis. Scand J Trauma Resusc Emerg Med, 2014, 22(1):54. 

Jiang L, Feng X, Ma Y, Zhang M. Red cell distribution width: a novel predictor of mortality in critically ill patients. J Thorac Dis, 2014, 6(9): E194-195. 

Jiang L, Jiang S, Zhang M, Zheng Z, Ma Y. Albumin versus Other Fluids for Fluid Resuscitation in Patients with Sepsis: A Meta-Analysis. PLoS ONE, 2014, 9(12): e114666. doi:10.1371/journal.pone.0114666.

Jiang L, Jiang S, Feng X, Ma Y, Zhang M. The efficacy and safety of different anticoagulants on patients with severe sepsis and derangement of coagulation: a protocol for network meta-analysis of randomized controlled trials. BMJ open, 2014, 4(12): e006770.

Yi HX, Zhang M, Wang JY, Luo RB, Jiang SY, Wang JA. Determination of protein phosphatase type 2A in monocytes from multiple trauma patients: a potential biomarker for sepsis. J Surg Res, 2014, 189(1):89-95.

Lu X, Zhang M, Yang JX, Xu SX, Gan JX. Preliminary experience of intracranial lesions by ultrasound in multiple trauma patients undergoing craniectomy. Hong Kong J Emerg Med, 2013, 20(1): 34-39. 

Shen P, Luo RB, Cai SY, Zhang M. Electroversion of atrial fibrillation in a patient with Wolff-Parkinson-White Syndrome and cervical spinal cord injury. Chin J Trauma, 2013, 16(3):176-177.

Shen P, Zong YM, Shu J, Shi YC, Zhu WJ, Qian HJ, Yang MX, Zhang M. Dynamic assessment of lung injury by ultrasound in a case with H7N9 influenza. Critical Care, 2013, 17: 438.  

Xu SX, Wang L, Zhou GJ, Zhang M, Gan JX. Risk factors and clinical significance of trauma-induced coagulopathy in ICU patients with severe trauma. Eur J Emerg Med, 2013, 20(4):286-290.

Zhou GJ, Jiang SY, Zhang M, Gan JX, Jiang GY. Evaluation of the inflammatory response in a two-hit acute lung injury model using [18F] FDG microPET. Experimental and Therapeutic Medicine, 2013, 6: 894-898. 

Li Q, Jiang Y, Zhang M. National representation in the emergency medicine literature: a bibliometric analysis of highly cited journals. Am J Emerg Med, 2012, 30(8):1530-1534. 

Gao YZ, Zhou GJ, Zhang M, Chen SQ, Gan JX. Rapid detection of recurrent intraventricular hemorrhage by ultrasound in a multiple trauma patient who had undergone craniectomy. Critical Care, 2012, 16: 459.

Ye LG, Zhou GJ, He XJ, Shen WF, Gan JX, Zhang M. Prolonged length of stay in the emergency department in high acuity patients at a Chinese tertiary hospital. Emerg Med Australas, 2012, 24(6): 634-640.

Zhang M, Ding W. Bedside ultrasonography for evaluation of pneumothorax. Chest, 2012, 141(3): 827-828.

Zhang M, Zhou GJ, Zhao S, Yang JX, Lu X, Gan JX, Xu SW. Delayed diagnosis of tooth aspiration in three multiple trauma patients with mechanical ventilation. Critical Care, 2011, 15(3): 424. 

Ding W, Shen YH, Yang JX, He XJ, Zhang M. Diagnosis of pneumothorax by radiography and ultrasonography-a Meta-analysis. Chest, 2011, 140(4): 859-866. 

Luo RB, Zhang M, Gan JX. Tracheobronchial malposition of fine bore feeding tube in patients with mechanical ventilation. Critical Care, 2011, 15: 454. 

Zhang M, Zhou GJ, Wang XD, Wang L, Gan JX, Xu SW. Invasive Pulmonary and Central Nervous System Aspergillosis following slops aspiration in a trauma patient. Critical Care,  2010, 14(5): 442. 

Zhang M, Liu ZH, Yang JX, Gan JX, Xu SW, You XD, Jiang GY. Rapid detection of pneumothorax by ultrasonography in patients with multiple trauma. Crit Care, 2006, 10(4): R112.

Current Program

Clinician-performed ultrasound for rapid assessment of major trauma patients.

Radiation exposure in major trauma patients.

Traumatic coagulopathy and damage control resuscitation.

Hypothermia in cardiac arrest.

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